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The Role of Barrier Dysfunction and Change of Claudin Expression in Inflammatory Bowel Disease

Kim TI

No abstract available.
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Effects of Mannose on Pathogenesis of Acanthamoeba castellanii

Yoo KT, Jung SY

  • KMID: 1792133
  • Korean J Parasitol.
  • 2012 Dec;50(4):365-369.
Acanthamoeba spp. are single-celled protozoan organisms that are widely distributed in the environment. In this study, to understand functional roles of a mannose-binding protein (MBP), Acanthamoeba castellanii was treated with...
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Comparative Analysis of Serum Mannose-Binding Lectin in Normal Population and Patients with Different Types of Cancer

Kim BJ, Kim YS, Han EM, Lee ES, Won NH, Ahn GH, Lee D, Yeom BW

  • KMID: 2073841
  • Korean J Pathol.
  • 2004 Oct;38(5):306-310.
BACKGROUND: Mannose-binding lectin (MBL) is a serum protein of innate immunity. Its genetic mutations lead to deficiency of serum MBL and recurrent pyogenic infection in childhood. However, little is known...
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Association of Mannose Binding Lectin Gene Polymorphisms with the Development of Kawasaki Disease: A Pilot Study

Choi EH, Kim HS, Lee HJ, Choi JY

PURPOSE: We hypothesized that the mannose binding lectin gene (MBL2), a key molecule of innate immunity may contribute to the development of Kawasaki disease (KD) in early childhood. This study...
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Serial Changes in Mannose-Binding Lectin in Patients with Sepsis

Huh JW, Song K, Kim HJ, Yum JS, Hong SB, Lim CM, Koh Y

BACKGROUND: Mannose-binding lectin (MBL) deficiency leads to increased susceptibility to infection. We investigated whether serial changes in MBL levels are associated with the prognosis of patients diagnosed with septic shock,...
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Innate Immunity and Genetic Susceptibility to Severe Respiratory Syncytial Virus Infection : Lack of an Association with Mannose Binding Lectin Gene Polymorphism

Choi EH, Kim HS, Yun BY, Choi SE, Nah SY, Kim DH, Park KW, Lee HJ

PURPOSE: We hypothesized that mannose binding lectin gene(MBL2), a key molecule of innate immunity, may contirbute to the development and the outcome of respiratory syncytial virus(RSV) disease in early childhood....
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Lack of Association between Hepatitis B Virus Infection and Polymorphism of Mannose-Binding Lectin Gene in Korean Population

Cheong JY, Cho SW, Lim SK, Shin DH, Yoon SK, Lee JE, Hahm KB, Kim JH

Mannose-binding lectin (MBL) plays an important role in immune defense. This study was undertaken to investigate the association between hepatitis B virus infection and polymorphisms of MBL gene. We assessed...
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Association of Single-Nucleotide Polymorphisms of the MBL2 with Atopic Dermatitis in Korean Patients

Kim JS, Lee SY, Hahn HJ, Lee YB, Yu DS, Kim JW

BACKGROUND: Human mannose-binding lectin (MBL) is a serum lectin taking part in the innate immunity by opsonizing various microorganisms for phagocytosis. The MBL serum concentration is affected by several single-nucleotide...
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Polymorphism of Codon 54 and Promoter of Mannose-binding Lectin Gene in Korean Atopic Dermatitis Patients

  • KMID: 2299777
  • Korean J Asthma Allergy Clin Immunol.
  • 2005 Mar;25(1):16-22.
BACKGROUND: Atopic dermatitis (AD) is an IgE mediated hypersensitivity reaction, generally considered to be caused by interaction of genetic and environmental factors. Human mannose-binding lectin (MBL) belongs to a group...
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Increased serum surfactant protein-D in the infants with acute respiratory syncytial virus bronchiolitis

Chu MA, Lee EJ, Park HJ, Lee KH, Kim WT, Chung HL

PURPOSE: Collectin family is an important component of innate immunity, of which surfactant protein (SP)-D and mannose-binding lectin (MBL) are the most characterized. We examined SP-D and MBL in young...
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Association of MBL With Work-Related Respiratory Symptoms in Bakery Workers

Kim MA, Yoon MK, Kim SH, Park HS

Baker's asthma is the most prevalent occupational asthma, and IgE-mediated response is known as a major pathogenesis. However, recent studies have suggested the involvement of innate immune response because wheat...
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Vascular health late after Kawasaki disease: implications for accelerated atherosclerosis

Cheung YF

Kawasaki disease (KD), an acute vasculitis that primarily affects young children, is the most common acquired paediatric cardiovascular disease in developed countries. While sequelae of arterial inflammation in the acute...
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Effects of MBL2 polymorphisms in patients with diisocyanate-induced occupational asthma

Kim SH, Bae SJ, Palikhe S, Ye YM, Park HS

Diisocyanate (DI) is the most common cause of occupational asthma (OA) in Korea. Mannose-binding lectin (MBL) initiates the lectin complement activation pathway following oxidative stress and plays an important role...
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Changes in the Expression and Distribution of Claudins, Increased Epithelial Apoptosis, and a Mannan-Binding Lectin-Associated Immune Response Lead to Barrier Dysfunction in Dextran Sodium Sulfate-Induced Rat Colitis

Yuan B, Zhou S, Lu Y, Liu J, Jin X, Wan H, Wang F

BACKGROUND/AIMS: This animal study aimed to define the underlying cellular mechanisms of intestinal barrier dysfunction. METHODS: Rats were fed 4% with dextran sodium sulfate (DSS) to induce experimental colitis. We analyzed...
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