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Combination Therapy with Rituximab and Temozolomide for Recurrent and Refractory Primary Central Nervous System Lymphoma

Murakami M, Fujimaki T, Asano S, Nakaguchi , Yamada SM, Hoya K, Yamazaki K, Ishida Y, Matsuno A

High-dose methotrexate-based chemotherapy has extended survival in patients with primary central nervous system lymphoma (PCNSL). However, although salvage treatment is necessary in recurrent and refractory PCNSL, this has not been...
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Cytomegalovirus appendicitis with concurrent bacteremia after chemotherapy for acute leukemia

Cho MJ, Lee J, Hu JY, Lee JW, Cho SY, Lee DG, Lee S

No abstract available.
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A Case of Primary Intraocular Lymphoma Treated by Intravitreal Methotrexate

Kim E, Kim C, Lee J, Cho Y

A 40-year-old female visited our clinic for visual disturbance of the right eye, in which a few creamy-yellow retinal lesions and visual field constrictions were noted. She had been treated...
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Factors Influencing the Response to High Dose Methotrexate-based Vincristine and Procarbazine Combination Chemotherapy for Primary Central Nervous System Lymphoma

Sung KH, Lee EH, Kim YZ

The authors investigated objective response rate to high dose methotrexate (HDMTX)-based combination chemotherapy in primary central nervous system lymphoma (PCNSL), and sought to identify factors that influence response to HDMTX-based...
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Outcomes of a Modified CALGB 19802 Regimen in Adult Acute Lymphoblastic Leukemia

Han AR, Kim K, Jang JH, Kim WS, Ahn JS, Jung CW, Lee MH, Kang WK

We analyzed the efficacy and toxicity of a modified Cancer and Leukemia Group B (CALGB) 19802 regimen in adult acute lymphoblastic leukemia (ALL). From February 2002 to August 2005, 25...
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A study of hepatitis B virus reactivation associated with rituximab therapy in real-world clinical practice: a single-center experience

Oh MJ, Lee HJ

BACKGROUND/AIMS: The widespread use of cytotoxic chemotherapy and immunosuppressants has resulted in reactivation of hepatitis B virus (HBV) recently becoming an issue. Although rituximab (an anti-CD20 monoclonal antibody) has revolutionized...
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Improvement of Induction Remission Rate by Modifying the Dose of Idarubicin for Relapsed Childhood Acute Lymphoblastic Leukemia

Yoon JH, Park JA, Kim EK, Kang HJ, Shin HY, Ahn HS

Relapse is the major cause of treatment failure in acute lymphoblastic leukemia (ALL), yet there is no established treatment for relapsed ALL. To improve the induction remission rate, we modified...
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Irreversible Paraplegia Following One Time Prophylactic Intrathecal Chemotherapy in an Adult Patient with Acute Lymphoblastic Leukemia

Lee HY, Im SI, Kang MH, Kim KM, Kim SH, Kim HG, Kang JH, Lee GW

  • KMID: 2396099
  • Yonsei Med J.
  • 2008 Feb;49(1):151-154.
We present an adult female patient who developed irreversible paraplegia and areflexia four days post intrathecal chemotherapy with methotrexate, cytosine arabinoside and hydrocortisone. On magnetic resonance imaging (MRI) of the...
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