- Dysregulation of ENaC in Animal Models of Nephrotic Syndrome and Liver Cirrhosis
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Kim SW
- KMID: 2052266
- Electrolyte Blood Press.
- 2006 Mar;4(1):23-34.
- doi: 10.5049/EBP.2006.4.1.23
Nephrotic syndrome and liver cirrhosis are common clinical manifestations, and are associated with avid sodium retention leading to the development of edema and ascites. However, the mechanism for the sodium... -
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- Pharmacodynamic Changes of Atracurium during Induced Liver Cirrhosis Using Carbon Tetrachloride Intoxication in Rabbits
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Kim KS, Jang HS, Cheong MA, Shim JC, Kim KH
- KMID: 2091958
- Korean J Anesthesiol.
- 2005 Jan;48(1):70-75.
- doi: 10.4097/kjae.2005.48.1.70
BACKGROUND: Atracurium appears to be a neuromuscular blocking agent best suited for use in patients with renal failure. The influence on the neuromuscular effect of atracurium has been studied in... -
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- Changes in Serum Cytokine Concentration: A Morphological Study of Liver Cirrhosis Induced by Common Bile Duct Ligation in Rats
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Lee BS, Kim NJ, Jeong HY, Lee HY, Kang DY, Noh SM
- KMID: 759628
- Korean J Intern Med.
- 2003 Mar;18(1):6-12.
BACKGROUND: Liver cirrhosis is a diffuse hepatic fibrosis and nodule formation. The transforming growth factor-beta1 (TGF-beta1) and interleukin-10 (IL-10) are very important cytokines in hepatic fibrogenesis. The aim of this... -
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- Protein Expression Profiles in a Rat Cirrhotic Model Induced by Thioacetamide
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An JH, Seong J, Oh H, Kim W, Han KH, Paik YH
- KMID: 760634
- Korean J Hepatol.
- 2006 Mar;12(1):93-102.
BACKGROUND/AIMS: The reactive oxygen species from thioacetamide (TAA) induces rat liver cirrhosis that resembles the human disease, and it can serve as a suitable animal model for studying human... -
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- Thalidomide Accelerates the Degradation of Extracellular Matrix in Rat Hepatic Cirrhosis via Down-Regulation of Transforming Growth Factor-beta1
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Lv P, Meng Q, Liu J, Wang C
- KMID: 2345885
- Yonsei Med J.
- 2015 Nov;56(6):1572-1581.
- doi: 10.3349/ymj.2015.56.6.1572
PURPOSE: The degradation of the extracellular matrix has been shown to play an important role in the treatment of hepatic cirrhosis. In this study, the effect of thalidomide on the... -
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- The effect of preconditioning on liver regeneration after hepatic resection in cirrhotic rats
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Min SO, Kim SH, Lee SW, Cho JA, Kim KS
- KMID: 1015573
- Korean J Hepatol.
- 2011 Jun;17(2):139-147.
- doi: 10.3350/kjhep.2011.17.2.139
BACKGROUND/AIMS: Ischemic preconditioning (IP) decreases severity of liver necrosis and has anti-apoptotic effects in previous studies using liver regeneration in normal rats. This study assessed the effect of IP on... -
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- Mest Attenuates CCl4-Induced Liver Fibrosis in Rats by Inhibiting the Wnt/beta-Catenin Signaling Pathway
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Li W, Zhu C, Li Y, Wu Q, Gao R
- KMID: 1774562
- Gut Liver.
- 2014 May;8(3):282-291.
BACKGROUND/AIMS: The Wnt/beta-catenin signaling pathway has been reported to play an important role in liver fibrosis. This study was designed to investigate whether mesoderm-specific transcript homologue (Mest), a strong negative... -
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- Antifibrotic effects of magnesium lithospermate B on hepatic stellate cells and thioacetamide-induced cirrhotic rats
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Paik YH, Yoon YJ, Lee HC, Jung MK, Kang SH, Chung SI, Kim JK, Cho JY, Lee KS, Han KH
- KMID: 1107375
- Exp Mol Med.
- 2011 Jun;43(6):341-349.
- doi: 10.3858/emm.2011.43.6.037
Magnesium lithospermate B (MLB) is one of the major active components of Salvia miltiorrhizae. The anti-oxidative effects of Salvia miltiorrhizae have been previously reported. The aim of this study was... -
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- Relationship of Propranolol Pharmacokinetic Parameters with Portosystemic Shunt in CCl4-induced cirrhotic Rats
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Koh DH, Park GT, Kim JM, Yun YS, Lee SH, Kim DU, Kim JB, Choi YY, Kang JS, Choi HS, Hahm JS, Lee MH
- KMID: 863098
- Korean J Hepatol.
- 2002 Sep;8(3):277-287.
BACKGROUND: This study was designed to determine the relationship of propranolol pharmacokinetic parameters with portosystemic shunt in CCl4-induced cirrhotic rats. METHODS: Cirrhotic rats(n=6) were induced by intramuscular injection of... -
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- Inhibitory Effect of Angiotensin Blockade on Hepatic Fibrosis in Common Bile Duct-ligated Rats
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Park DH, Baik SK, Choi YH, Kim MY, Rhim DW, Kim JW, Kwon SO, Cho MY, Kim CH, Ahn SC
- KMID: 760706
- Korean J Hepatol.
- 2007 Mar;13(1):61-69.
BACKGROUNDS AND AIMS: Angiotensin receptors are found on hepatic stellate cells, which participate in hepatic fibrosis. Therefore, it is presumed that angiotensin has a role in hepatic fibrosis. The... -
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- Serum hyaluronic acid level: Correlation with quantitative measurement of hepatic fibrosis in a cirrhotic rat model
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Kim MY, Baik SK, Jang YO, Suk KT, Kim JW, Kim HS, Cho MY, Choi SJ, Um SH, Han KH
- KMID: 760780
- Korean J Hepatol.
- 2008 Jun;14(2):159-167.
- doi: 10.3350/kjhep.2008.14.2.159
BACKGROUNDS/AIMS: The serum level of hyaluronic acid (HA) has been suggested as a useful serologic marker for hepatic fibrosis. However, the relationship between serum HA levels and quantitative markers... -
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- Suppressive Effects of Antioxidant DA-9601 on Hepatic Fibrosis in Rats
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Cheong JY, Oh TY, Lee KM, Kim DH, Ahn BO, Kim WB, Kim YB, Yoo BM, Hahm KB, Kim JH, Cho SW
- KMID: 863119
- Korean J Hepatol.
- 2002 Dec;8(4):436-447.
BACKGROUND/AIMS: Oxidative stress is one of the important underlying mechanisms of hepatic fibrosis. DA-9601, the ethanol extracts of Artemisia asiatica, has been reported to possess strong antioxidative and cytoprotective... -
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