- Lipid A as a Drug Target and Therapeutic Molecule
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Joo SH
- KMID: 2380301
- Biomol Ther.
- 2015 Nov;23(6):510-516.
- doi: 10.4062/biomolther.2015.117
In this review, lipid A, from its discovery to recent findings, is presented as a drug target and therapeutic molecule. First, the biosynthetic pathway for lipid A, the Raetz pathway,... -
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- Regulation of mouse macrophage Fc receptor-mediated phagocytosis by interferon-r, lipid a and tumor necrosis factor
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Kim JG
- KMID: 1690586
- Korean J Immunol.
- 1993 May;15(1):45-51.
No abstract available. -
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- Effect of Intravenous Lipid Emulsion in the Patient with Acute Poisoning : A Systematic Review
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Myung J, Ko DR, Kong T, Joo YS, You JS, Chung SP
- KMID: 1846317
- J Korean Soc Clin Toxicol.
- 2015 Jun;13(1):1-10.
PURPOSE: The purpose of this study was to evaluate the usefulness of intravenous lipid emulsion as well as adverse events in acute poisoning patients. METHODS: Literature was accessed through PubMed, EMBASE,... -
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- In-vivo 1H MR Spectroscopy in Abscessess Induced in Rabbit Thighs: Evaluation of Treatment Effect
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Goo JM, Chang KH, Lee KH, Han MH, Song IC
- KMID: 1516297
- J Korean Soc Magn Reson Med.
- 2003 Jun;7(1):31-38.
PURPOSE: To analyze the serial changes of proton magnetic resonance (MR) spectra in the abscess and to determine the effect of the antibiotic treatment on the metabolite patterns. MATERIALS AND... -
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- Distinct Effects of Monophosphoryl Lipid A, Oligodeoxynucleotide CpG, and Combination Adjuvants on Modulating Innate and Adaptive Immune Responses to Influenza Vaccination
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Ko EJ, Lee YT, Lee Y, Kim KH, Kang SM
- KMID: 2400638
- Immune Netw.
- 2017 Oct;17(5):326-342.
- doi: 10.4110/in.2017.17.5.326
Monophosphoryl lipid A (MPL) and oligodeoxynucleotide CpG are toll-like receptor (TLR) 4 and 9 agonist, respectively. Here, we investigated the effects of MPL, CpG, and combination adjuvants on stimulating in... -
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- Differences in Colistin-resistant Acinetobacter baumannii Clinical Isolates Between Patients With and Without Prior Colistin Treatment
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Park YJ, Hong DJ, Yoon EJ, Kim D, Choi MH, Hong JS, Lee H, Yong D, Jeong SH
- KMID: 2429120
- Ann Lab Med.
- 2018 Nov;38(6):545-554.
- doi: 10.3343/alm.2018.38.6.545
BACKGROUND: The increasing morbidity and mortality rates associated with Acinetobacter baumannii are due to the emergence of drug resistance and the limited treatment options. We compared characteristics of colistin-resistant Acinetobacter... -
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- Monophosphoryl lipid A (MPL) upregulates major histocompatibility complex (MHC) class I expression by increasing interferon-gamma (IFN-gamma)
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Cho CH, Lee BK, Kwak SM, Kim JD
- KMID: 1099874
- Yonsei Med J.
- 1999 Feb;40(1):20-25.
- doi: 10.3349/ymj.1999.40.1.20
Tumor immunity is primarily mediated by cells as CD8+ cytotoxic T lymphocytes (CTL) recognize tumor antigen by MHC class I molecules. But most tumors are associated with a... -
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- Induction of Bronchial Tolerance After 1 Cycle of Monophosphoryl-A-Adjuvanted Specific Immunotherapy in Children With Grass Pollen Allergies
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Rosewich M, Girod K, Zielen S, Schubert R, Schulze J
- KMID: 2391046
- Allergy Asthma Immunol Res.
- 2016 May;8(3):257-263.
- doi: 10.4168/aair.2016.8.3.257
PURPOSE: Subcutaneous allergen-specific immunotherapy (SCIT) is a well-established and clinically effective method to treat allergic diseases, such as rhinitis and asthma. It remains unclear how soon after initiation of an... -
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- A Current Research Insight into Function and Development of Adjuvants
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Sohn ES, Son E, Pyo S
- KMID: 2167974
- Immune Netw.
- 2004 Sep;4(3):131-142.
- doi: 10.4110/in.2004.4.3.131
In recent years, adjuvants have received much attention because of the development of purified subunit and synthetic vaccines which are poor immunogens and require adjuvants to evoke the immune response.... -
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- Genetic Variants Associated with Calorie and Macronutrient Intake in a Genome-Wide Association Study
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Baik I, Ahn Y, Lee SK, Kim S, Han BG, Shin C
- KMID: 2268024
- Korean J Nutr.
- 2010 Aug;43(4):357-366.
- doi: 10.4163/kjn.2010.43.4.357
There has been no genome-wide association study (GWAS) for macronutrient intake as a quantitative trait. To explore genetic loci associated with total calorie and macronutrient intake, genome-wide association data of... -
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- Identification of a Lymphocyte Mitogenic Factor Produced by Actinobacillus actinomycetemcomitans
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Seo SY, Jeong SJ, Yoo SH, Park SM, Jeong MH, Yee ST, Kim JM, Song JM, Jo WS, Lee SH
- KMID: 2099300
- J Korean Soc Microbiol.
- 1998 Oct;33(5):521-535.
Actinobacillus actinomycetemcomitans, a gram-negative, capnophiTic bacterium, is associated with several human diseases including periodontal disease. Products of A. actinomycetemcomitans exert immunomodulatory effects on various lymphoid populations, some of which may... -
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- Discovery of Diagnostic Biomarkers for Legionnaires' Disease: Virulence Gene Expression Profiling of Legionella pneumophila serogroup 1 in A/J Mouse Model
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Kim SM, Sim HS, Kim HS, Shim HK, Yoon YK, Kim JY, Park YS, Park DW, Sohn JW, Kim MJ
- KMID: 2170276
- Infect Chemother.
- 2010 Feb;42(1):23-29.
- doi: 10.3947/ic.2010.42.1.23
BACKGROUND: Legionella pneumophila is the causative agent of Legionnaires' disease, a severe form of pneumonia. After L. pneumophila is inhaled through contaminated aerosols, it is phagocytized by alveolar macrophages, multiplies... -
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- Vaccination with a Human Papillomavirus (HPV)-16/18 AS04-Adjuvanted Cervical Cancer Vaccine in Korean Girls Aged 10-14 Years
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Kim YJ, Kim KT, Kim JH, Cha SD, Kim JW, Bae DS, Nam JH, Ahn WS, Choi HS
- KMID: 1714043
- J Korean Med Sci.
- 2010 Aug;25(8):1197-1204.
- doi: 10.3346/jkms.2010.25.8.1197
The human papillomavirus (HPV)-16/18 AS04-adjuvanted cervical cancer vaccine has been demonstrated to be highly efficacious and immunogenic with a favorable safety profile. This study assessed the immunogenicity and safety of... -
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