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Development and validation of a UPLC-MS/MS method for the quantification of acetaminophen in human plasma and its application to pharmacokinetic studies

Cha J, Kim BK, Gwon MR, Lee J, Ohk B, Kang WY, Lim MS, Seong SJ, Kim HJ, Lee HW, Yoon YR

We developed an ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for the determination of acetaminophen concentration in human plasma. Following protein precipitated extraction, the analytes were separated and analyzed using...
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Two cases of spontaneous rupture of the kidney

Moon HG, Choi HS, Lim YS, Lim MS, Lee KH, Ahn HJ

  • KMID: 2060417
  • Korean J Urol.
  • 1992 Aug;33(4):753-757.
Spontaneous rupture of the kidney with subcapsular or perinephric hemorrhage usually occurs secondary to various kinds of underlying diseases such as benign malignant tumor. vascular disease and infection etc. We...
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A case of extragonadal germ cell tumor

Lim MS, Choi HS, Lim YS, Moon HG, Lee KH, Ahn HJ

  • KMID: 2060419
  • Korean J Urol.
  • 1992 Aug;33(4):761-764.
Extragonadal germ cell tumors are rare. accounting for approximately 38 of all germ cell tumors. Debate continues over whether these lesions originate from extragonadal site or are metastatic disease from...
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Analysis of Research Trends Using G-power in Physiotherapy Research in Korea: Systematic Review

Baek KH, Lim MS, Park MH, Seo HA, Hyeon DA, Lim Hw

Purpose: This study examined the research trends using G-power centered on major Korean registered sites and presents the research trends of studies with a high level of evidence. Method: This study...
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Hybrid Nanofiber Scaffold-Based Direct Conversion of Neural Precursor Cells/Dopamine Neurons

Lim MS, Ko SH, Kim MS, Lee B, Jung HS, Kim K, Park CH

The concept of cellular reprogramming was developed to generate induced neural precursor cells (iNPCs)/dopaminergic (iDA) neurons using diverse approaches. Here, we investigated the effects of various nanoscale scaffolds (fiber, dot,...
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Neutron therapy for prostatic cancer

Lim YS, Lim MS, Moon HK, Lee KH, Ahn HJ, Yoo SY

  • KMID: 2289389
  • Korean J Urol.
  • 1992 Dec;33(6):979-984.
The neutron beam has higher relative biological effectiveness (RBE) than conventional X or gamma ray because it is densely ionizing radiation which is presented by high linear energy transfer (LET)....
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Operative Treatment of Chronic Recurrent Dislocation of Peroneal Tendon: A Case Report

Lee DY, Kang JD, Lim MS, Yoon HJ

  • KMID: 2063698
  • J Korean Foot Ankle Soc.
  • 2007 Jun;11(1):120-122.
Traumatic dislocation of the peroneal tendon is an infrequent injury. This injury is caused by forceful dorsiflexion of the foot accompanied by a powerful contraction of the peroneal muscles. This...
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Peroneus Longus Dislocation associated with Trimalleolar Fracture: A Case Report

Hwang IH, Kim KY, Kim HC, Lim MS, Lee JH, Cho SJ

  • KMID: 1469374
  • J Korean Foot Ankle Soc.
  • 2009 Dec;13(2):227-229.
Traumatic dislocation of the peroneus longus tendon is an often unrecognized injury which has been reported to occur most commonly during sports activity. Most acute cases with early detection can...
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Population pharmacokinetic analysis of the multiple peaks phenomenon in sumatriptan

Lee J, Lim MS, Seong SJ, Park SM, Gwon MR, Han S, Lee SM, Kim W, Yoon YR, Yoo HD

The objective of this study was to develop a population pharmacokinetic (PK) model for sumatriptan, which frequently shows an atypical absorption profile with multiple peaks. Sumatriptan, a selective agonist for...
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Effects of the Instrument Pilates Exercise Based on the Schroth Exercise on the Cobb’s Angle, Angle of Trunk Rotation and Low Back Pain in Patients with Idiopathic Scoliosis: A Single Subject Study

Song KY, Baek KH, Lim MS, Lim Hw

Purpose: This study examined the effects of the application of Schroth exercise-based instrument Pilates exercise on the Cobb’s angle, angle of trunk rotation, and low back pain of female patients...
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Severe asthma exacerbation associated with COVID-19 in children: A case report

Yeh HR, Lim MS, Seo HJ, Lee EJ, Kim JG, Yum HY

Epidemiological evidence suggests that the severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is lesser and morbidity and mortality rates are lower in children than in adults. Although...
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Laparoscopic total extraperitoneal repair of lumbar hernia

Lim MS, Lee HW, Yu CH, Yang DH

Lumbar hernia is a rare surgical entity without a standard method of repair. With advancements in laparoscopic techniques, successful lumbar herniorrhaphy can be achieved by the creation of a completely...
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Steady-State Pharmacokinetic Properties of Tamsulosin in Healthy Male Volunteers

Seong SJ, Lee HW, Lee J, Lim MS, Kim EH, Park SM, Gwon MR, Yoon YR

BACKGROUND: To evaluate the pharmacokinetic properties of daily oral doses of tamsulosin administered to fasted healthy Korean male volunteers for 5 days. METHODS: In a randomized, open-label, multiple-dose, two-period, crossover study,...
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Small Bowel Intussusception in Children: Spontaneous Resolution vs. Surgical Intervention

Park MR, Lim MS, Seo JK, Ko JS, Chang JY, Yang HR, Lim YJ, Kim WS

PURPOSE: Intussusception is one of the most common causes of an acute abdomen in infancy. The majority of pediatric cases of intussusception are of the ileocolic type and usually idiopathic....
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Acroosteolysis of Scleroderma Associated with a Felon

Hwang IH, Lim MS, Kim KY, Kim HC, Moon SH, Lee JH, Cho SJ

The Scleroderma is a chronic inflammatory disease of the connective tissue with involvement of the skin and other organs. It can be a manifestation of various disorders and occasionally acroosteolysis...
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Two Cases of Extrapelvic endometriosis following Laparoscopy-assisted vaginal hysterectomy and Cesarean section

Bae JJ, Lim MS, Koh MW, Lee TH, Kim MJ

  • KMID: 2320158
  • Yeungnam Univ J Med.
  • 2007 Jun;24(1):91-96.
Extrapelvic endometriosis is a rare disease. The majority of extrapelvic endometriosis cases involve scar tissue following obstetric and gynecologic procedures. We have treated two cases of extrapelvic incisional endometriosis. A...
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Analysis and suggestions on medical educators’ roles

Joo M, Chae Ym, Lim MS, Park Sg

Purpose: This study aimed to investigate the differences in the perception between professors and students regarding medical educators’ roles and discuss their desirable roles. Methods: A survey was administered to 116...
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Single agent chemotherapy with cyclophosphamide in patients with advanced prostatic cancer

Lim MS, Lee KH

  • KMID: 2289363
  • Korean J Urol.
  • 1993 Aug;34(4):626-630.
Eleven patients with advanced prostatic cancer who had received single agent chemotherapy with cyclophosphamide were evaluated. All patients had pathologically confirmed prostatic adenocarcinoma and were unresponsive to or in relapse...
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FGF8 is Essential for Functionality of Induced Neural Precursor Cell-derived Dopaminergic Neurons

Lim MS, Lee SY, Park CH

Induced neural precursor cells (iNPCs) are one source of transplantable dopaminergic neurons used in cell therapy for Parkinson's disease. In the present study, we demonstrate that iNPCs can be generated...
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Clinical Pharmacokinetics of Caffeine in Korean Preterm Infants with Apnea of Prematurity

Lim MS, Son MJ, Shin JE, Lee SM, Eun HS, Park MS, Park KI, Namgung R

PURPOSE: Caffeine shows wide interindividual pharmacokinetic (PK) variation, and therapeutic drug monitoring (TDM) may be needed. The PK profile of caffeine in Korean preterm neonates was investigated, and factors influencing...
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