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Oxcarbazepine Induced Leukopenia

Son YR, Kim YS, Chu K, Lee SK

  • KMID: 1431584
  • J Korean Epilepsy Soc.
  • 2013 Jun;17(1):22-23.
Oxcarbazepine (OXC) is generally assumed to be safe with regard to the risk for adverse hematopoietic effects. Recently, pancytopenia and leukopenia associated with the treatment of OXC have been reported....
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Efficacy of Adenine in the Treatment of Leukopenia and Neutropenia Associated with an Overdose of Antipsychotics or Discontinuation of Lithium Carbonate Administration: Three Case Studies

Tomita T, Goto H, Sumiya K, Yoshida T, Tanaka K, Kohda Y

Because adenine is effective for managing cases of radiation-induced and drug-induced leukopenia, it may be effective in cases of antipsychotic-induced leukopenia and neutropenia. Here, we report our experience with patients...
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Two Cases of Acute Leukopenia Induced by Colchicine with Concurrent Immunosuppressants Use in Behcet's Disease

Lee KY, Kim DY, Chang JY, Bang D

  • KMID: 2396104
  • Yonsei Med J.
  • 2008 Feb;49(1):171-173.
Colchicine-induced leukopenia usually occurrs in intentional or accidental overdoses or inappropriate use in combination with intravenous and oral colchine; however, there have been several reports of hematologic toxicity in short-term...
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A Case of Adult-onset Still's Disease Associated with Leukopenia

Lee HS, Jung JW, Shin DH, Song HJ, Choi JH, Suh YJ, Nahm DH, Park HS, Suh CH

  • KMID: 2025593
  • J Korean Rheum Assoc.
  • 2003 Jun;10(2):176-180.
Adult-onset Still's disease (AOSD) is a multi-systemic inflammatory disorder characterized by high spiking fever, evanescent salmon-colored rash, arthralgia or arthritis, leukocytosis and the involvement of various organs. However, leukopenia is...
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Isolated leukopenia during antituberculosis treatment

Song HH, Lim CM, Lee SD, Koh YS, Kim WS, Kim DS, Kim WD, Shim TS

BACKGROUND: Isolated leukopenia is rare, but it has important clinical implications during antituberculosis treatment. Inadvertent discontinuation of short-course regimen drugs for fear of leukopenia inevitably will extend the duration of treatment, and...
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Neutropenia with Multiple Antipsychotics Including Dose Dependent Neutropenia with Lurasidone

Sood S

Antipsychotic-induced agranulocytosis is a significant side effect that is known to occur with most of the antipsychotic medications. It usually resolves once the medications are stopped and patients are able...
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A Study on the Leukopenia during Chemotherapy in Patients with Gynecologic Malignancies

Cho SH, Kim KT, Moon H, Hwang YY, Moon YJ, Bae JW

  • KMID: 1928706
  • Korean J Gynecol Oncol Colposc.
  • 2000 Jun;11(2):131-139.
The recent introduction of chemotherapy in the treatment of the gynecologic malignancies has gained wide acceptance along with preoperative and postoperative adjuvant therapy and with preradiation and concurrent chemoradiaton therapy....
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Clinical effects of recombinant human granulocyte-macrophage colony-stimulating factor(rh GM-CSF) in patients with leukopenia after cancer chemotherapy

Hong JS, Park SK, Lee KH, Rhu SS, Jung JK, Namgoong S, Kim SJ, Lee HY

  • KMID: 2259745
  • Korean J Obstet Gynecol.
  • 1993 Jul;36(7):2993-2999.
No abstract available.
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Lung Pathology in Septic Shock with Leukopenia

Huh GY

Sepsis-related deaths are occasionally encountered in forensic practice. However, forensic pathologists are reluctant to use the terminology “sepsis” or “septic shock” as a cause of death because of the lack...
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Evaluation of hematologic profile may be needed for patients treated with oxcarbazepine

Jung GH, You SJ

PURPOSE: The major side effects of treatment with oxcarbazepine (OXC) are skin rash and hyponatremia. Hematologic side effects are reported rarely. The aim of this study was to investigate the...
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The Clinical Effect of Recombinant Human Granulocyte-Colony Stimulating Factor to the Leukopenia During Chemotherapy in the Patients with Gynecologic Malignancies

Choi IS, Son JM, Kim H, Yoo GS, An JM, Kim WG, Park UD

  • KMID: 1675679
  • Korean J Gynecol Oncol Colposc.
  • 1996 Jun;7(2):100-109.
An increase in the dose of chemotherapy enhances the response of many experimental and clinical cancers, but the extent of chemotherapy dose escalation and repeated use is often limited by...
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A Case of Aplastic Anemia in Pregnancy

Park YH, Park JY, Lim SY, Lee DO, Cho Y, Ro ES, Shin DH

  • KMID: 2272351
  • Korean J Obstet Gynecol.
  • 2004 May;47(5):992-995.
Pregnancy complicated by aplastic anemia is uncommon condition with the significant morbidity and mortality rates. the main complication to mother is hemorrhage due to thrombocytopenia and sepsis due to leukopenia...
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A Clinical Observation of the Intravesical Thiotepa in Bladder Cancer

Min KS, Park KH

  • KMID: 1911380
  • Korean J Urol.
  • 1981 Apr;22(2):195-199.
Primary transitional cell carcinoma of the bladder was treated with prophylactic and therapeutic Intravesical thiotepa in 7 cases. In 5 cases of stage A tumor, postoperative follow up was averaged...
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Severe Leukopenia after Intravenous Cyclophosphamide Pulse Therapyin a Patient Having Cytochrome P450 2A6*1B

Seong SS, Yun JH, Kim EY, Shin JG, Jun JB, Bae SC

Cyclophosphamide, a prodrug requiring metabolic activation by cytochrome P450 (CYP) enzymes, is used widely for proliferative lupus nephritis and various CYP isoenzymes have been demonstrated to be involved in the...
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Three Cases of Anticonvulsant Hypersensitivity Syndrome Associated with Lamotrigine

Cho YW, Lee H, Sohn SI, Jung DK, Lim JG, Yi SD

  • KMID: 1582548
  • J Korean Neurol Assoc.
  • 2002 Jan;20(1):79-81.
Among the various side effects of anticonvulsant medication, the anticonvulsant hypersensitivity syndrome (AHS) is underrecognized. This condition developed frequently with aromatic anticonvulsants, but with new antiepileptic drugs as well. We...
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A Case of Atypical Kawasaki Disease with Severe Neutropenia

Kwon EJ, Lee SI, Song MS, Chi GH, Kim CH

  • KMID: 1511253
  • J Korean Pediatr Cardiol Soc.
  • 2007 Jun;11(2):138-141.
Leukocytosis and neutrophilia is common during the acute phase of Kawasaki disease whereas leukopenia is not common and severe neutropenia is rare. Severe neutropenia is defined as absolute neutrophil count...
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A case of Methimazole-Induced Cholestatic Jaundice With Agranulocytosis

Kang SG, Bae JO, Lee EY, Lim SM, Cho SK, Kim JH, Song SK

Methimazole is a widely used and generally well-tolerated antithyroid agent. Adverse reactions occur in 1~5% of patients taking methimazole medication, but these are most commonly transient, benign leukopenia and a...
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Mycoplasma pneumoniae-associated Hepatitis without Lung Involvement

Jeong HT, Oh JY, Song JE, Kim BS, Lee CH

Mycoplasma pneumoniae (M. pneumoniae) is a major cause of community acquired respiratory infections. And it also causes a number of extrapulmonary manifestations including cardiovascular, dermatological, musculoskeletal, and hematological systems. But,...
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The Frequency and the Course of the Adverse Effects of Azathioprine/6-Mercaptopurine Treatment in Patients with Inflammatory Bowel Disease

Kim JH, Cheon JH, Kim WH

  • KMID: 1767529
  • Korean J Gastroenterol.
  • 2008 May;51(5):291-297.
BACKGROUND/AIMS: This study was to evaluate the frequency and the course of the adverse effects of AZA/6-MP in Korean patients with inflammatory bowel disease (IBD). METHODS: Medical records of the...
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Two Cases of Reversible Neutropenia Associated with Olanzapine-Valproate Combination Treatment

Kang SH, Oh JK, Lee JI, Chang AK

  • KMID: 2341834
  • J Korean Neuropsychiatr Assoc.
  • 2010 Nov;49(6):653-656.
The novel antipsychotic, olanzapine, has structural and pharmacological properties similar to clozaine. Antipsychotic drugs, as well as mood stabilizers, can cause neutropenia, which can progress to life-threatening agranulocytosis if the...
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