- Leukostasis by hyperleukocytic childhood acute leukemia: pathophysiology, clinical presentation, and emergency care
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Nam KL, Baek GY, Jeon IS
- KMID: 2469716
- Pediatr Emerg Med J.
- 2019 Dec;6(2):35-41.
- doi: 10.22470/pemj.2019.00150
Hyperleukocytosis (HL), defined by a peripheral white blood cell (WBC) count exceeding 100,000/mm³, is occasionally observed in childhood acute leukemia. The increased viscosity in the micro-circulation by HL and the... -
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- Enumeration of CD34-positive Stem Cells Using the ADAMII Image-based Fluorescence Cell Counter
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Yu H, Yoo J, Hwang JS, Kim M, Bae KH, Jekarl DW, Oh JH, Lee JY, Han S, Chung C, Kim M, Kim Y
- KMID: 2438886
- Ann Lab Med.
- 2019 Jul;39(4):388-395.
- doi: 10.3343/alm.2019.39.4.388
BACKGROUND: It is very important to accurately enumerate CD34-positive (CD34+) cells for successful hematopoietic stem cell transplantation (HSCT). We evaluated the ability of the newly developed image based-immunofluorescence cell counter... -
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- Expression of adhesion molecules on CD34+ cells from steady-state bone marrow before and after mobilization and their association with the yield of CD34+ cells
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Cecyn KZ, Kimura EY, Lima DM, Yamamoto M, Bordin JO, de Oliveira JSR
- KMID: 2414366
- Blood Res.
- 2018 Mar;53(1):61-70.
- doi: 10.5045/br.2018.53.1.61
BACKGROUND: Cell adhesion molecules (CAMs) expressed on hematopoietic progenitor cells (HPCs), endothelial cells, and stromal cells play a pivotal role in the mobilization of CD34+ cells. Herein, we conducted a... -
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- Differences in Mobilization Efficiency between Small Children and Adults with Healthy Marrows
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Shin EK, Kim DY, Rah WJ, Koh H, Suh JY, Chang M, Nam E, Lee YH
- KMID: 2396014
- Clin Pediatr Hematol Oncol.
- 2017 Oct;24(2):130-135.
- doi: 10.15264/cpho.2017.24.2.130
BACKGROUND: We compared the yields of mobilized PBSCs from single day of normal volume leukapheresis (NVL) in children and adults, and factors affecting the yields, to understand differences in mobilization... -
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- Adsorptive Granulocyte and Monocyte Apheresis in the Treatment of Ulcerative Colitis: The First Multicenter Study in China
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Lai YM, Yao WY, He Y, Jiang X, Gu YB, Chen MH, Liu YL, Yuan YZ, Qian JM
- KMID: 2412187
- Gut Liver.
- 2017 Mar;11(2):216-225.
- doi: 10.5009/gnl15408
BACKGROUND/AIMS: Patients with active ulcerative colitis (UC) have elevated levels of activated myeloid-derived leukocytes as a source of inflammatory cytokines. The selective depletion of these leukocytes by adsorptive granulocyte/monocyte apheresis... -
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- Ultrasound-guided percutaneous portal transplantation of peripheral blood monocytes in patients with liver cirrhosis
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Yu SJ, Yoon JH, Kim W, Lee JM, Lee YB, Cho Y, Lee DH, Lee M, Yoo JJ, Cho EJ, Lee JH, Kim YJ, Kim CY
- KMID: 2371648
- Korean J Intern Med.
- 2017 Mar;32(2):261-268.
- doi: 10.3904/kjim.2015.267
BACKGROUND/AIMS: Liver transplantation offers the only definite cure for cirrhosis but lacking donors is problem. Stem cell therapy is attractive in this setting. In this study, we aimed to explore... -
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- Therapeutic Leukapheresis for the Management of Hyperleukocytosis: Ten-year Experience in a Tertiary Care Hospital
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Kim B, Lee K, Kim S, Kim HO
- KMID: 2308731
- Lab Med Online.
- 2016 Jul;6(3):159-164.
- doi: 10.3343/lmo.2016.6.3.159
BACKGROUND: Hyperleukocytosis is a medical emergency that is characterized by increased blood viscosity and predisposition to various neurological, pulmonary, and gastrointestinal complications. In addition, patients are at risk of the... -
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- Autologous Stem Cells Transplantation in Egyptian Patients with Liver Cirrhosis on Top of Hepatitis C Virus
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Al Tayeb H, El Dorry A, Amer N, Mowafy N, Zimaity M, Bayoumy E, Saleh SA
- KMID: 2380815
- Int J Stem Cells.
- 2015 Nov;8(2):209-218.
- doi: 10.15283/ijsc.2015.8.2.209
BACKGROUND AND OBJECTIVES: Use of pluripotent stem cells is an ideal solution for liver insufficiencies. This work aims is to evaluate the safety and feasibility of autologous stem cells transplantation... -
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- Favorable outcome of allogeneic hematopoietic stem cell transplantation followed by post-transplant treatment with imatinib in children with Philadelphia chromosome-positive acute lymphoblastic leukemia
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Byun YJ, Suh JK, Lee SW, Lee D, Kim H, Choi ES, Koh KN, Im HJ, Seo JJ
- KMID: 2172757
- Blood Res.
- 2015 Sep;50(3):147-153.
- doi: 10.5045/br.2015.50.3.147
BACKGROUND: Allogeneic hematopoietic stem cell transplantation (HSCT) is the preferred curative therapy for children with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL). We evaluated the treatment outcomes of children with... -
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- Correlation between the Severity of Bone Pain and the Amount of CD34+ Cells after Peripheral Blood Stem Cell Mobilization
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Seo JW, Choi JS, Kim YH, Yoon SS, Park S, Han KS
- KMID: 2255808
- Korean J Blood Transfus.
- 2015 Aug;26(2):123-131.
- doi: 10.17945/kjbt.2015.26.2.123
BACKGROUND: Peripheral blood stem cells (PBSCs) are mobilized by granulocyte-colony stimulating factor (G-CSF), which causes several side effects in allogeneic donors. We report on side effects of G-CSF administration and... -
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- Radiation Therapy for Central Retinal Vein Occlusion with Macular Edema in Acute Lymphocytic Leukemia
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Lee JY, Lim DH, Jung CW, Kim SJ
- KMID: 2216167
- J Korean Ophthalmol Soc.
- 2015 Jan;56(1):134-137.
- doi: 10.3341/jkos.2015.56.1.134
PURPOSE: Central retinal vein occlusion (CRVO) as a complication of acute leukemia has rarely been reported. Here, we report a favorable outcome of radiation therapy for CRVO with severe macular... -
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- Factors Predicting Peripheral Blood Stem Cell Collection: Analysis of Korean Patients at a Single Center
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Jang MJ, Cho D, Shin MG, Ryang DW
- KMID: 2090036
- Korean J Blood Transfus.
- 2014 Dec;25(3):260-273.
- doi: 10.0000/kjbt.2014.25.3.260
BACKGROUND: Peripheral blood stem cell (PBSC) transplantation is a curative treatment in various hematologic malignancies and some solid cancers. Effective mobilization and collection of PBSC is essential for successful PBSC... -
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- Clinical Effects and Safety of Therapeutic Leukapheresis in Hyperleukocytosis
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Lee SN, Kong JH, Eom HS, Lee H, Park HJ, Sohn JY, Kong SY
- KMID: 2029269
- Korean J Blood Transfus.
- 2014 Aug;25(2):132-140.
- doi: 10.0000/kjbt.2014.25.2.132
BACKGROUND: Therapeutic leukapheresis is the cytoreduction procedure performed before chemotherapy in patients with hyperleukocytosis for prevention of complication. However, there have been clinical concerns about bleeding tendency due to anticoagulant... -
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- Loss of Red Cell A Antigen in a Patient with Acute Myeloid Leukemia: A Case Report and Review of the Literature
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Cho JH, Hur M, Moon HW, Yun YM, Lee MH, Han SH
- KMID: 1442286
- Korean J Blood Transfus.
- 2011 Dec;22(3):277-283.
Red cell antigens, A, B, and H can be weakened or lost especially in patients with hematologic malignancies. We report a 42-year-old female patient with acute myeloid leukemia, who showed... -
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- Advances in ulcerative colitis therapy
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Jeen YT, Kim J
- KMID: 2257258
- Korean J Med.
- 2009 Jun;76(6):654-660.
Ulcerative colitis is an idiopathic inflammatory bowel disease characterized by colonic mucosal inflammation and chronic relapsing episodes. The initial therapeutic approach depends on both the extent of colonic involvement and... -
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- Factors to Predict Autologous CD34 Positive Cells Harvest in the Patients with Malignant Lymphoproliferative Disorder
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Lee SM, Kwon MJ, Kang MJ, Lee EJ, Lee WS, Sohn CH, Lee JY, Lee JN, Kim H, Joo YD
- KMID: 2252174
- Korean J Hematol.
- 2009 Mar;44(1):47-52.
- doi: 10.5045/kjh.2009.44.1.47
BACKGROUND: Autologous peripheral blood stem cell transplantation (PBSCT) has been used as a major treatment strateg for malignant lymphoproliferative disorder. The number of CD34 positive cells in the harvested product... -
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- Cytapheresis in Patients with Severe Ulcerative Colitis after Failure of Intravenous Corticosteroid: A Long-Term Retrospective Cohort Study
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Fukunaga K, Nagase K, Kusaka T, Hida N, Ohda Y, Yoshida K, Tozawa K, Kamikozuru K, Iimuro M, Nakamura S, Miwa H, Matsumoto
- KMID: 1744239
- Gut Liver.
- 2009 Mar;3(1):41-47.
BACKGROUND/AIMS: Cytapheresis (CAP) is a novel strategy for ulcerative colitis (UC). However, there is insufficient data on the long-term outcome of UC patients who achieve remission by CAP. This study... -
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- Effect of the G-CSF schedule for harvesting peripheral blood progenitor cells from healthy donors
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Lee SE, Park JY, Lee SW, Choi IJ, Lee SJ, Park CW
- KMID: 2256066
- Korean J Med.
- 2008 Nov;75(5):553-558.
BACKGROUND/AIMS: Peripheral blood progenitor cells (PBSC) have been used instead of bone marrow cells for allogeneic transplantation. Progenitor cells are mobilized using granulocyte colony stimulating factor (G-CSF). Kinetic studies of... -
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- A Case of Ulcerative Colitis with Prolonged Remission Following Azathioprine-Induced Pancytopenia
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Lee JS, Park YS, Kim NI, Jo YJ, Kim SH, Lee HH, Song MH, Jun DW
- KMID: 2174073
- Intest Res.
- 2008 Jun;6(1):85-89.
Azathioprine (AZA) is widely used for the treatment of inflammatory bowel disease. Bone marrow suppression is a common side effect with AZA treatment. However, data from AZA trials has indicated... -
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- Effect of Leukapheresis on Gene Expression Profiles of Donor's Peripheral Blood Mononuclear Cells
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Shin JW, Jin P, Stroncek D
- KMID: 854843
- Korean J Lab Med.
- 2008 Apr;28(2):130-135.
- doi: 10.3343/kjlm.2008.28.2.130
BACKGROUND: Leukapheresis has commonly been used to obtain the cell products intended for clinical cell therapy. Hypocalcemia related to citrate toxicity and some circulatory effects such as hypovolemia and... -
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