- Personalized Medicine in Cardiovascular Diseases
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Lee MS, Flammer AJ, Lerman LO, Lerman A
- KMID: 2297887
- Korean Circ J.
- 2012 Sep;42(9):583-591.
- doi: 10.4070/kcj.2012.42.9.583
Personalized medicine is a novel medical model with all decisions and practices being tailored to individual patients in whatever ways possible. In the era of genomics, personalized medicine combines the... -
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- The Decline Effect in Cardiovascular Medicine: Is the Effect of Cardiovascular Medicine and Stent on Cardiovascular Events Decline Over the Years?
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Lee MS, Flammer AJ, Lerman A
- KMID: 2145499
- Korean Circ J.
- 2013 Jul;43(7):443-452.
- doi: 10.4070/kcj.2013.43.7.443
The term decline effect is referred to a diminution of scientifically discovered effects over time. Reasons for the decline effect are multifaceted and include publication bias, selective reporting, outcomes reporting... -
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- Three Dimensional Quantitative Coronary Angiography Can Detect Reliably Ischemic Coronary Lesions Based on Fractional Flow Reserve
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Chung WY, Choi BJ, Lim SH, Matsuo Y, Lennon RJ, Gulati R, Sandhu GS, Holmes DR, Rihal CS, Lerman A
- KMID: 2160599
- J Korean Med Sci.
- 2015 Jun;30(6):716-724.
- doi: 10.3346/jkms.2015.30.6.716
Conventional coronary angiography (CAG) has limitations in evaluating lesions producing ischemia. Three dimensional quantitative coronary angiography (3D-QCA) shows reconstructed images of CAG using computer based algorithm, the Cardio-op B system... -
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- The Prevalence of Cardiovascular Disease Risk Factors and the Framingham Risk Score in Patients Undergoing Percutaneous Intervention Over the Last 17 Years by Gender: Time-trend Analysis From the Mayo Clinic PCI Registry
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Lee MS, Flammer AJ, Kim HS, Hong JY, Li J, Lennon RJ, Lerman A
- KMID: 2381419
- J Prev Med Public Health.
- 2014 Jul;47(4):216-229.
- doi: 10.3961/jpmph.2014.47.4.216
OBJECTIVES: This study aims to investigate trends of cardiovascular disease (CVD) risk factor profiles over 17 years in percutaneous coronary intervention (PCI) patients at the Mayo Clinic. METHODS: We performed a... -
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- Tissue Characterization of Coronary Plaques Using Intravascular Ultrasound/Virtual Histology
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Bae JH, Rihal CS, Lerman A
- KMID: 1859062
- Korean Circ J.
- 2006 Aug;36(8):553-558.
- doi: 10.4070/kcj.2006.36.8.553
Most studies related with plaque histopathology and/or morphology are based on the gray scale intravascular ultrasound (IVUS) and autopsy findings, although IVUS is limited for differentiating echolucent areas, and tissue... -
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- Ultrastructural changes of the internal elastic lamina in experimental hypercholesterolemic porcine coronary arteries
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Kwon HM, Kim D, Hong BK, Byun KH, Oh SH, Kna JS, Kim HS, Schwartz R, Lerman A
- KMID: 1038440
- J Korean Med Sci.
- 1998 Dec;13(6):603-611.
- doi: 10.3346/jkms.1998.13.6.603
The internal elastic lamina (IEL) serves as a barrier for cells and macromolecules between the intima and media in the vascular wall. We evaluated the morphological changes and quantitative... -
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- Serum Uric Acid is Associated with Cardiovascular Events in Patients with Coronary Artery Disease
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Bae JH, Hyun DW, Kwon TG, Yoon HJ, Lerman A, Rihal CS
- KMID: 2227073
- Korean Circ J.
- 2007 Apr;37(4):161-166.
- doi: 10.4070/kcj.2007.37.4.161
BACKGROUND AND OBJECTIVES: Whether uric acid is a predictor of cardiovascular events remains controversial. We sought to evaluate the effects of the serum uric acid levels on major adverse cardiovascular... -
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- Hypertension, a Low Ejection Fraction and Severe Angiographic Findings are Associated with Smooth Muscle Dysfunction in Patients with Coronary Atherosclerosis
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Bae JH, Rihal CS, Hyun DW, Park KR, Kwon TG, Yoon HJ, Lerman A
- KMID: 2227047
- Korean Circ J.
- 2007 Oct;37(10):470-474.
- doi: 10.4070/kcj.2007.37.10.470
BACKGROUND AND OBJECTIVES: Nitroglycerin-mediated arterial dilation (NMD) was shown to be preserved in most previous studies, and this is possibly due to using a single high dose of nitroglycerin (NTG),... -
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- Impact of Plaque Composition on Long-Term Clinical Outcomes in Patients with Coronary Artery Occlusive Disease
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Kim KH, Kim WH, Park HW, Song IG, Yang DJ, Seo YH, Yuk HB, Park YH, Kwon TG, Rihal CS, Lerman A, Lee MS, Bae JH
- KMID: 2224898
- Korean Circ J.
- 2013 Jun;43(6):377-383.
- doi: 10.4070/kcj.2013.43.6.377
BACKGROUND AND OBJECTIVES: It is unclear which plaque component is related with long-term clinical outcomes in patients with coronary artery occlusive disease (CAOD). We assessed the relationship between plaque compositions... -
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