- Vaccine strategies utilizing C-type lectin receptors on dendritic cells in vivo
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Park CG
- KMID: 1730619
- Clin Exp Vaccine Res.
- 2014 Jul;3(2):149-154.
- doi: 10.7774/cevr.2014.3.2.149
Dendritic cells (DCs) are professional antigen-presenting cells capable of initiating and regulating innate and adaptive immunity. The development of effective ways to produce a large number of DCs in laboratories... -
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- Dendritic Cell Functions in Allergen Recognition and Response
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Han M
- KMID: 2314366
- Pediatr Allergy Respir Dis.
- 2005 Jun;15(2):87-97.
Dendritic cells (DCs) are crucial in the defense against pathogens and allergen. The ability of allergens to cause allergic inflammation is contingent upon the presence of microenvironment that either privileges... -
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- The Innate Immune Response in House Dust Mite-Induced Allergic Inflammation
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Wang JY
- KMID: 2260340
- Allergy Asthma Immunol Res.
- 2013 Mar;5(2):68-74.
- doi: 10.4168/aair.2013.5.2.68
Hypersensitivity to house dust mite (HDM; Dermatophagoides sp.) allergens is one of the most common allergic responses, affecting up to 85% of asthmatics. Sensitization to indoor allergens is the strongest... -
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- Dectin-1 Stimulation Selectively Reinforces LPS-driven IgG1 Production by Mouse B Cells
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Seo BS, Lee SH, Lee JE, Yoo YC, Lee J, Park SR
- KMID: 1493615
- Immune Netw.
- 2013 Oct;13(5):205-212.
- doi: 10.4110/in.2013.13.5.205
Dectin-1, which specifically recognizes beta-glucan of fungal cell walls, is a non-Toll-like receptor (TLR) pattern recognition receptor and a representative of C-type lectin receptors (CLRs). The importance of Dectin-1 in... -
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- Integrin CD11b negatively regulates Mincle-induced signaling via the Lyn–SIRPα–SHP1 complex
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Zhang Q, Lee WB, Kang JS, Kim LK, Kim YJ
- KMID: 2440021
- Exp Mol Med.
- 2018 Feb;50(2):e439.
- doi: 10.1038/emm.2017.256
During mycobacteria infection, anti-inflammatory responses allow the host to avoid tissue damage caused by overactivation of the immune system; however, little is known about the negative modulators that specifically control... -
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- Inflammasomes, multi-cellular protein complex in myeloid cells, induce several metabolic diseases via interleukin-1beta maturation
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Lee GS
- KMID: 1703511
- J Biomed Res.
- 2013 Dec;14(4):195-200.
Inflammation mainly mediated by innate immune cells as the first line of host defense against pathogens is an acute response that limits tissue damage and eliminates pathogens in the body.... -
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- Selectins: functional importance as cell adhesion molecule in immune system
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Noh Y, Cho D, Ko H, Lim D, Chai HH
- KMID: 2470310
- J Biomed Transl Res.
- 2019 Dec;20(4):75-81.
- doi: 10.12729/jbtr.2019.20.4.075
Selectins are cell membrane glycoproteins that recognize specific glycoconjugates expressed on the surface of cells. Then, selectins adjust cell-cell interactions that are important in inflammation, hemostasis and cancer metastasis. Selectins... -
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- Comparative study of synonymous codon usage variations between the nucleocapsid and spike genes of coronavirus, and C-type lectin domain genes of human and mouse
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Ahn I, Jeong BJ, Son HS
- KMID: 1009396
- Exp Mol Med.
- 2009 Oct;41(10):746-756.
- doi: 10.3858/emm.2009.41.10.081
Coronaviruses (CoVs) are single-stranded RNA viruses which contain the largest RNA genomes, and severe acute respiratory syndrome coronavirus (SARS-CoV), a newly found group 2 CoV, emerged as infectious disease with... -
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- CD72 is a Negative Regulator of B Cell Responses to Nuclear Lupus Self-antigens and Development of Systemic Lupus Erythematosus
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Tsubata T
- KMID: 2438909
- Immune Netw.
- 2019 Feb;19(1):e1.
- doi: 10.4110/in.2019.19.e1
Systemic lupus erythematosus (SLE) is the prototypic systemic autoimmune disease characterized by production of autoantibodies to various nuclear antigens and overexpression of genes regulated by IFN-I called IFN signature. Genetic... -
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- Potentiation of Innate Immunity by beta-Glucans
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Seong SK, Kim HW
- KMID: 2312582
- Mycobiology.
- 2010 Jun;38(2):144-148.
beta-Glucans have been known to exhibit antitumor activities by potentiating host immunity by an unknown mechanism. The C-type lectin dectin-1, a beta-glucan receptor, is found on the macrophage and can... -
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- Overexpression of SOX9 in mouse embryonic stem cells directs the immediate chondrogenic commitment
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Kim JH, Do HJ, Yang HM, Oh JH, Choi SJ, Kim DK, Cha KY, Chung HM
- KMID: 1093460
- Exp Mol Med.
- 2005 Aug;37(4):261-268.
Mouse embryonic stem (mES) cells are capable of undergoing chondrogenesis in vitro. To enhance this process, the human SOX9 (hSOX9) cDNA was delivered into mES cells and the clones overexpressing... -
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