- A proposed framework for holding intensive 3Rs workshops in laboratory animal science
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Ahmadi-Noorbakhsh S, Sadighi J, Hatami Z, Gooshki ES
- KMID: 2527826
- Lab Anim Res.
- 2022 Mar;38(1):67-71.
- doi: 10.1186/s42826-022-00120-9
Principles of 3Rs are the backbone of today’s animal research. Applying 3Rs in practice requires proper education and training. Although this could be achieved via long-term courses ranging from several... -
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- Pulmonary vein aneurysm in a New Zealand White rabbit: a case report
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Kim JM, Woo CG, Kim SH, Jeong ES, Kim KS, Kang BC
- KMID: 2527823
- Lab Anim Res.
- 2022 Mar;38(1):53-56.
- doi: 10.1186/s42826-022-00114-7
Background: Pulmonary venous aneurysm (PVA) is a rare condition characterized by aneurysmal dilatation of the pulmonary vein in humans. The diagnosis is incidental usually as there are no clinical symptoms.... -
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- The endocannabinoid system in zebrafish and its potential to study the effects of Cannabis in humans
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Bailone RL, Fukushima HCS, Aguiar LKd, Borra RC
- KMID: 2527818
- Lab Anim Res.
- 2022 Mar;38(1):6-17.
- doi: 10.1186/s42826-022-00116-5
Zebrafish is considered an unprecedented animal model in drug discovery. A review of the literature presents highlights and elucidates the biological effects of chemical components found in Cannabis sativa. Particular... -
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- Disease predictability review using common biomarkers appearing in diabetic nephropathy and neurodegeneration of experimental animals
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Yi SS
- KMID: 2527817
- Lab Anim Res.
- 2022 Mar;38(1):1-5.
- doi: 10.1186/s42826-022-00113-8
It is recently known that the kidney and brain have a very rich distribution of blood vessels, and the histological structures of micro-vessels are very similar. Therefore, a number of... -
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- Diagnosis and treatment of macrocytic anemia in a perinatal common marmoset: a case report
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Kim JM, Kwak J, Lim HJ, Kim JI, Kang BC
- KMID: 2527824
- Lab Anim Res.
- 2022 Mar;38(1):57-60.
- doi: 10.1186/s42826-022-00115-6
Background: The common marmoset is widely used in current biomedical research for various research fields. We observed macrocytic anemia in a perinatal common marmoset with gradual weight loss and diarrhea.... -
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- Single injection of very mild dose botulinum toxin in the vastus lateralis improves testicular spermatogenesis and sperm motility in ageing experimental mice
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Radhakrishnan RK, Ravichandran S, Sukesh A, Kadalmani B, Kandasamy M
- KMID: 2527821
- Lab Anim Res.
- 2022 Mar;38(1):34-44.
- doi: 10.1186/s42826-022-00117-4
Background: Botulinum toxin (BoNT) is a widely used therapeutic agent that blocks the excessive release of acetylcholine at the neuromuscular junction. Previously, repeated intracremasteric injections and slight overdose of BoNT... -
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- Feasibility of non-invasive recording of somatosensory evoked potential in pigs
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Hoareau GL, Peters A, Hilgart D, Iversen M, Clark G, Zabriskie M, Rieke V, Floyd C, Shah L
- KMID: 2527825
- Lab Anim Res.
- 2022 Mar;38(1):61-66.
- doi: 10.1186/s42826-022-00118-3
Background: Non-invasive measurement of somatosensory-evoked potentials (SEP) in a large animal model is important to translational cognitive research. We sought to develop a methodology for neurophysiological recording via a transcranial... -
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- Loss-of-function mutation in Pcsk1 increases serum APOA1 level and LCAT activity in mice
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Khan AA, Kim N, Korstanje R, Choi S
- KMID: 2527819
- Lab Anim Res.
- 2022 Mar;38(1):18-26.
- doi: 10.1186/s42826-021-00111-2
Background: The convertase subtilisin/kexin family 1 gene (PCSK1) has been associated in various human genetics studies with a wide spectrum of metabolic phenotypes, including early-onset obesity, hyperphagia, diabetes insipidus, and... -
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- Therapeutic effect of intra-articular injected 3′-sialyllactose on a minipig model of rheumatoid arthritis induced by collagen
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Kim YJ, Lee Jy, Yang Mj, Cho HJ, Kim My, Kim L, Hwang JH
- KMID: 2527822
- Lab Anim Res.
- 2022 Mar;38(1):45-52.
- doi: 10.1186/s42826-022-00119-2
Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease of joint, but there is no known cure. 3′-sialyllactose (3′-SL) is an oligosaccharide that is abundant in breast milk of mammals, and... -
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- Ultrasonographic and macroscopic study of pregnancy in golden hamster
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Keshavarz MA, Mogheiseh A, Ahrari-Khafi MS, Mahboobi R
- KMID: 2527820
- Lab Anim Res.
- 2022 Mar;38(1):27-33.
- doi: 10.1186/s42826-022-00112-9
Background: Hamster is widely used as an experimental model in the study of reproductive system. However, pregnancy diagnosis and aging always have been a challenge. ultrasonography have been used in... -
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