- Zootechnical data analysis in a breeding animal facility: tracing the patterns of mouse production
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Ferreira EKGD, Mazzarotto GACA, Silveira GF
- KMID: 2514373
- Lab Anim Res.
- 2021 Mar;37(1):32-43.
- doi: 10.1186/s42826-020-00082-w
Background: With the enactment of the Brazilian Law Arouca 11,794/2008 and Decree 6.899/2009, there has been an urgent need for changes in the processes related to animal experimentation in Brazil;... -
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- Nonhuman primate model in mammary gland biology and neoplasia research
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Dewi FN, Cline JM
- KMID: 2514369
- Lab Anim Res.
- 2021 Mar;37(1):1-10.
- doi: 10.1186/s42826-020-00053-1
Research on breast cancer pathogenesis, prevention and drug development remains an important field as this disease is still one of the leading causes of cancer death worldwide. Nonhuman primates, particularly... -
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- Establishment and application of information resource of mutant mice in RIKEN BioResource Research Center
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Masuya H, Usuda D, Nakata H, Yuhara N, Kurihara K, Namiki Y, Iwase S, Takada T, Tanaka N, Suzuki K, Yamagata Y, Kobayashi N, Yoshiki A, Kushida T
- KMID: 2514372
- Lab Anim Res.
- 2021 Mar;37(1):21-31.
- doi: 10.1186/s42826-020-00068-8
Online databases are crucial infrastructures to facilitate the wide effective and efficient use of mouse mutant resources in life sciences. The number and types of mouse resources have been rapidly... -
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- A review of studies on Oryzias dancena
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Park IS
- KMID: 2514371
- Lab Anim Res.
- 2021 Mar;37(1):11-20.
- doi: 10.1186/s42826-020-00081-x
Oryzias dancena (Beloniformes; Teleostei), is a euryhaline teleost that mainly inhabits the brackish or freshwater of river mouths and estuaries around the Bay of Bengal and the Malay Peninsula. It... -
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- Quercetin attenuates the reduction of parvalbumin in middle cerebral artery occlusion animal model
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Park DJ, Kang JB, Shah FA, Koh PO
- KMID: 2514399
- Lab Anim Res.
- 2021 Mar;37(1):74-81.
- doi: 10.1186/s42826-021-00086-0
Background: Calcium is a critical factor involved in modulation of essential cellular functions. Parvalbumin is a calcium buffering protein that regulates intracellular calcium concentrations. It prevents rises in calcium concentrations... -
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- Inflammatory responses of C57BL/6NKorl mice to dextran sulfate sodium-induced colitis: comparison between three C57BL/6 N sub-strains
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Kim SH, Kwon D, Son SW, Jeong TB, Lee S, Kwak JH, Cho JY, Hwang DY, Seo MS, Kim KS, Jung YS
- KMID: 2514398
- Lab Anim Res.
- 2021 Mar;37(1):67-73.
- doi: 10.1186/s42826-021-00084-2
Background: Inflammatory bowel disease (IBD), including both Crohn’s disease and ulcerative colitis, are chronic human diseases that are challenging to cure and are often unable to be resolved. The inbred... -
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- Comparison of response to LPS-induced sepsis in three DBA/2 stocks derived from different sources
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Park JW, Lee SJ, Kim JE, Kang MJ, Bae SJ, Choi YJ, Gong JE, Kim KS, Jung YS, Cho JY, Choi YS, Hwang DY, Song HK
- KMID: 2514374
- Lab Anim Res.
- 2021 Mar;37(1):44-52.
- doi: 10.1186/s42826-020-00079-5
Sepsis, one of the most fatal diseases in the world, is known to culminate in multiple organ failure due to an uncontrolled inflammatory response. Hence, the use of animal models... -
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- Tail suspension is useful as a sarcopenia model in rats
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Nemoto A, Goyagi T
- KMID: 2514397
- Lab Anim Res.
- 2021 Mar;37(1):60-66.
- doi: 10.1186/s42826-020-00083-9
Background Sarcopenia promotes skeletal muscle atrophy and exhibits a high mortality rate. Its elucidation is of the highest clinical importance, but an animal experimental model remains controversial. In this study, we... -
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- Sex-dependent liver cancer xenograft models for predicting clinical data in the evaluation of anticancer drugs
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Oh S, Jung J
- KMID: 2514400
- Lab Anim Res.
- 2021 Mar;37(1):82-89.
- doi: 10.1186/s42826-021-00087-z
Background The incidence and mortality of liver cancer show a great difference between the sexes. We established sex-dependent liver cancer xenograft models and investigated whether such sex-dependent models could be used... -
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- Lipopolysaccharides of Fusobacterium nucleatum and Porphyromonas gingivalis increase RANKL-expressing neutrophils in air pouches of mice
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Kim AR, Lim YK, Kook JK, Bak EJ, Yoo YJ
- KMID: 2514396
- Lab Anim Res.
- 2021 Mar;37(1):53-59.
- doi: 10.1186/s42826-020-00080-y
Increases of neutrophils and osteoclasts are pathological changes of periodontitis. RANKL is an osteoclast differentiation factor. The effect of periodontopathogen LPS on RANKL-expressing neutrophils has not been clarified yet. We... -
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- Comparison of age‐dependent alterations in thioredoxin 2 and thioredoxin reductase 2 expressions in hippocampi between mice and rats
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Yoo YH, Kim DW, Chen BH, Sim H, Kim B, Lee JC, Ahn JH, Park Y, Cho JH, Kang IJ, Won MH, Lee TK
- KMID: 2514401
- Lab Anim Res.
- 2021 Mar;37(1):90-97.
- doi: joohee@duksung.ac.kr
Background Aging is one of major causes triggering neurophysiological changes in many brain substructures, including the hippocampus, which has a major role in learning and memory. Thioredoxin (Trx) is a class... -
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