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Hao J, Kim CH

No abstract available.
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Traumatic and Non-traumatic Osteonecrosis in the Femoral Head of a Rabbit Model

Hwang Y, Park J, Choi SH, Kim G

Osteonecrosis of the femoral head is an idiopathic, debilitating and progressive disease. A number of traumatic or non-traumatic animal models have been reported for research on osteonecrosis. This study was...
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Spontaneous Sertoli Cell Tumor with Cryptorchism in a Beagle Dog

Hong S, Lee HA, Han SJ, Kim O

A male one year-old beagle dog with unilateral cryptorchism was presented for investigation of reduced appetite. Abdominal sonography and radiography demonstrated abnormal enlargement of the left testicle in the abdominal...
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Sensitive and Specific Detection of Mycoplasma species by Consensus Polymerase Chain Reaction and Dot Blot Hybridization

Hong S, Lee HA, Park SH, Kim O

Mycoplasmas are highly fastidious bacteria, difficult to culture and slow growing. Many species of mycoplasmas are important pathogens that cause respiratory infection in laboratory animals and that are known to...
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Bone Marrow-Derived Mesenchymal Stem Cells Improve the Functioning of Neurotrophic Factors in a Mouse Model of Diabetic Neuropathy

Kim BJ, Jin HK, Bae JS

Diabetic neuropathy is one of the most frequent and troublesome complications of diabetes. Although there has been a continuous increase in the incidence of diabetic neuropathy, treatments have yet to...
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Difference in Resistance to Streptococcus pneumoniae Infection in Mice

Jeong DG, Jeong ES, Seo JH, Heo SH, Choi YK

Streptococcus pneumoniae is a major pathogen that causes various diseases, including pneumonia and sepsis, as millions of people suffer from S. pneumoniae infection worldwide. To better understand the immune and...
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OCT4 Expression Enhances Features of Cancer Stem Cells in a Mouse Model of Breast Cancer

Kim RJ, Nam JS

The cancer stem cell (CSC) hypothesis proposes that CSCs are responsible for metastasis and disease recurrence. Therefore, targeting CSCs has the potential to significantly improve outcomes for cancer patients. The...
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Animal Models of Periventricular Leukomalacia

Choi EK, Park D, Kim TK, Lee SH, Bae DK, Yang G, Yang YH, Kyung J, Kim D, Lee WR, Suh JG, Jeong ES, Kim SU, Kim YB

Periventricular leukomalacia, specifically characterized as white matter injury, in neonates is strongly associated with the damage of pre-myelinating oligodendrocytes. Clinical data suggest that hypoxia-ischemia during delivery and intrauterine or neonatal...
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Granulocyte-Derived Cationic Peptide Enhances Homing and Engraftment of Bone Marrow Stem Cells after Transplantation

Lee H, Che JH, Lee JC, Chung SS, Jung HS, Park KS

Current strategies to accelerate hematopoietic reconstitution after transplantation include transplantation of greater numbers of hematopoietic stem/progenitor cells (HSPCs) or ex vivo expansion of harvested HSPCs before transplant. However, the number...
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Epigallocatechin-3-gallate Regulates Inducible Nitric Oxide Synthase Expression in Human Umbilical Vein Endothelial Cells

Ahn HY, Kim CH

Inducible nitric oxide synthase (iNOS) is a main enzyme producing nitric oxide during inflammation and thus contributes to the initiation and development of inflammatory cardiovascular diseases such as atherosclerosis. Epigallocatechin-3-gallate...
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Isolation and Expression Profile of the Ca(2+)-Activated Chloride Channel-like Membrane Protein 6 Gene in Xenopus laevis

Lee RM, Ryu RH, Jeong SW, Oh SJ, Huang H, Han JS, Lee CH, Lee CJ, Jan LY, Jeong SM

To clone the first anion channel from Xenopus laevis (X. laevis), we isolated a calcium-activated chloride channel (CLCA)-like membrane protein 6 gene (CMP6) in X. laevis. As a first step...
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Gene Alterations of Ovarian Cancer Cells Expressing Estrogen Receptors by Estrogen and Bisphenol A Using Microarray Analysis

Hwang KA, Park SH, Yi BR, Choi KC

Since endocrine disrupting chemicals (EDCs) may interfere with the endocrine system(s) of our body and have an estrogenicity, we evaluated the effect(s) of bisphenol A (BPA) on the transcriptional levels...
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Detailed Differentiation of Calbindin D-28k-Immunoreactive Cells in the Dentate Gyrus in C57BL/6 Mice at Early Postnatal Stages

Yoo DY, Yoo KY, Park JH, Choi JW, Kim W, Hwang IK, Won MH

The hippocampus makes new memories and is involved in mental cognition, and the hippocampal dentate gyrus (DG) is critical because neurogenesis, which occurs throughout life, occurs in the DG. We...
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Transcriptome Analysis of the Effects of Gomisin A on the Recovery of Carbon Tetrachloride-Induced Damage in Rat Liver

Choi YM, Choi IS, Lee SM, Hwang DY, Choi YW, Park YH

Gomisin A possesses a hepatic function-facilitating property in liver-injured rats. Its preventive action on carbon tetrachloride-induced cholestasis is due to maintenance of the function of the bile acids-independent fraction. To...
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Effects of Steaming Time and Frequency for Manufactured Red Liriope platyphylla on the Insulin Secretion Ability and Insulin Receptor Signaling Pathway

Choi SI, Lee HR, Goo JS, Kim JE, Nam SH, Hwang IS, Lee YJ, Prak SH, Lee HS, Lee JS, Jang IS, Son HJ, Hwang DY

In oriental medicine, Liriope platyphylla (LP) has long been regarded as a curative herb useful for the treatment of diabetes, asthma, and neurodegenerative disorders. The principal objective of this study...
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