- Endothelium-Independent Effect of Fisetin on the Agonist-Induced Regulation of Vascular Contractility
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Je HD, Sohn UD, La HO
- KMID: 2170541
- Biomol Ther.
- 2016 Jan;24(1):57-61.
- doi: 10.4062/biomolther.2015.104
Fisetin, a natural flavonoid found in a variety of vegetables and fruits, has been shown to possess many biological functions. The present study was undertaken to investigate the influence of... -
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- The Inhibitory Effect of Shikonin on the Agonist-Induced Regulation of Vascular Contractility
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Je HD, Kim HD, La HO
- KMID: 2380332
- Biomol Ther.
- 2015 May;23(3):233-237.
- doi: 10.4062/biomolther.2014.148
Shikonin, a natural flavonoid found in the roots of Lithospermum erythrorhizon, has been shown to possess many biological functions. The present study was undertaken to investigate the influence of shikonin... -
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- Comparison of Usage Patterns and Outcomes by Dual Type Calcium Channel Blockers in Patients with Chronic Kidney Disease
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Oh MR, Ahn HL, Choi S, La HO
- KMID: 2510429
- Korean J Clin Pharm.
- 2020 Dec;30(4):259-263.
- doi: 10.24304/kjcp.2020.30.4.259
Background: Dual-type calcium channel blockers (CCBs), such as efonidipine and cilnidipine, are renoprotective drugs that reportedly reduce proteinuria by dilating afferent and efferent arterioles of the glomerulus. However, studies comparing... -
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- The Inhibitory Effect of Apigenin on the Agonist-Induced Regulation of Vascular Contractility via Calcium Desensitization-Related Pathways
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Je HD, Kim HD, La HO
- KMID: 2170648
- Biomol Ther.
- 2014 Mar;22(2):100-105.
Apigenin, a natural flavonoid found in a variety of vegetables and fruits, has been shown to possess many biological functions. The present study was undertaken to investigate the influence of... -
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- Signal Detection of Rosuvastatin Calcium Using Spontaneous Adverse Drug Event Reports
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Yoon HY, Choi IY, Yim HW, La HO
- KMID: 2534639
- J Pharmacoepidemiol Risk Manage.
- 2020 Sep;12(2):85-90.
Objective: The purpose of this study was to detect for the signals of rosuvastatin calcium applying a data mining analysis based on data of domestic adverse drug reaction reporting system... -
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- Analysis of L-asparaginase Related Adverse Reaction
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Ko KM, La HO
- KMID: 2405668
- Korean J Clin Pharm.
- 2017 Sep;27(3):143-149.
- doi: 10.24304/kjcp.2017.27.3.143
OBJECTIVE: L-asparaginase (L-ASP) is a critical agent for the treatment of acute lymphoblastic leukemia and lymphoma, which is associated with serious toxicities including hypersensitivity, pancreatitis and thrombosis. METHODS: To evaluate the... -
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- Hypothermia Inhibits Endothelium-Independent Vascular Contractility via Rho-kinase Inhibition
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Chung YH, Oh KW, Kim ST, Park ES, Je HD, Yoon HJ, Sohn UD, Jeong JH, La HO
- KMID: 2429053
- Biomol Ther.
- 2018 Mar;26(2):139-145.
- doi: 10.4062/biomolther.2016.233
The present study was undertaken to investigate the influence of hypothermia on endothelium-independent vascular smooth muscle contractility and to determine the mechanism underlying the relaxation. Denuded aortic rings from male... -
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- Practice Preferences on Dabigatran and Rivaroxaban for Stroke Prevention in Patients with Non-valvular Atrial Fibrillation
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Park YK, Kang JE, Kim SJ, La HO, Rhie SJ
- KMID: 2358236
- Korean J Clin Pharm.
- 2016 Sep;26(3):207-212.
- doi: 10.0000/kjcp.2016.26.3.207
OBJECTIVE: Prescription rate of dabigatran and rivaroxaban, which are the direct oral anticoagulants (DOAC), has increased. We have analyzed the prescription trend and medication use of dabigatran and rivaroxaban in... -
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- Endothelium Independent Effect of Pelargonidin on Vasoconstriction in Rat Aorta
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Min YS, Yoon HJ, Je HD, Lee JH, Yoo SS, Shim HS, Lee HY, La HO, Sohn UD
- KMID: 2420388
- Biomol Ther.
- 2018 Jul;26(4):374-379.
- doi: 10.4062/biomolther.2017.197
In this study, we investigated the effects of pelargonidin, an anthocyanidin found in many fruits and vegetables, on endothelium-independent vascular contractility to determine the underlying mechanism of relaxation. Isometric contractions... -
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- Severe Cutaneous Adverse Reactions to Antiepileptic Drugs: A Nationwide Registry-Based Study in Korea
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Park CS, Kang DY, Kang MG, Kim S, Ye YM, Kim SH, Park HK, Park JW, Nam YH, Yang MS, Jee YK, Jung JW, Kim SH, Kim CW, Kim MY, Kim JH, Lee J, Lee JG, Kim SH, La HO, Kim MH, Park SJ, Koh YI, Lee SM, Kwon YE, Jin HJ, Kim HK, Kang HR, Choi JH, Korean Registry of Severe Cutaneous Adverse Reactions Consortium
- KMID: 2452760
- Allergy Asthma Immunol Res.
- 2019 Sep;11(5):709-722.
- doi: 10.4168/aair.2019.11.5.709
PURPOSE: Severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms (DRESS) to antiepileptic drug (AED), are rare, but... -
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- Phenotypes of Severe Cutaneous Adverse Reactions Caused by Nonsteroidal Anti-inflammatory Drugs
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Lee SY, Nam YH, Koh YI, Kim SH, Kim S, Kang HR, Kim MH, Lee JG, Park JW, Park HK, La HO, Kim MY, Park SJ, Kwon YE, Jung JW, Kim SH, Kim CW, Yang MS, Kang MG, Lee JY, Kim JH, Kim SH, Hur GY, Jee YK, Jin HJ, Park CS, Jeong YY, Ye YM
- KMID: 2431853
- Allergy Asthma Immunol Res.
- 2019 Mar;11(2):212-221.
- doi: 10.4168/aair.2019.11.2.212
PURPOSE: Nonsteroidal anti-inflammatory drugs (NSAIDs) are common cause of severe cutaneous adverse reactions (SCARs). The present study aimed to investigate the characteristics of SCARs induced by NSAIDs in the Korean... -
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