- The structural change of rat cerebral cortex by the in situ perfusion with L-glutamate, glycine and kynurenate
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Kim KY, Lee WB, Kim DC
- KMID: 1686693
- Korean J Anat.
- 1992 Dec;25(4):418-429.
No abstract available. -
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- The Effects of N-Methyl_D-Aspartic Acid, and Antagonism by Kynurenic Acid on Neurons in the Cathish Retina
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Lee SJ, Jung CS, Bai SH
- KMID: 2205353
- J Korean Ophthalmol Soc.
- 1998 Oct;39(10):2303-2312.
To investigate the mechanism of the excitatory signal transmission, the effects of N-methyl-D-aspartate(NMDA, ionotropic glutamate agonist) and kynurenic acid(glutamate antagonist) on catfish retinal neurons were explored using conventional intracellular recording... -
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- Changes in Vestibular Nerve Activity Following Acute Hypotension in Rats
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Park BR, Kim MS, Yee GH, Moon MJ, Kim JH, Jin YZ, Kim YS
- KMID: 2285278
- Korean J Physiol Pharmacol.
- 2003 Apr;7(2):85-90.
The basic mechanism for the excitation of the peripheral vestibular receptors following acute hypotension induced by sodium nitroprusside (SNP) or hemorrhage was investigated in anesthetized rats. Electrical activity of the... -
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- The tryptophan utilization concept in pregnancy
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Badawy AA
- KMID: 1841535
- Obstet Gynecol Sci.
- 2014 Jul;57(4):249-259.
- doi: 10.5468/ogs.2014.57.4.249
The decrease in maternal plasma total (free + albumin-bound) tryptophan (Trp) during the third pregnancy trimester is attributed to induction of indoleamine 2,3-dioxygenase (IDO). When measured, free [Trp] is increased... -
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- Effects of glutamate receptor antagonists and protein synthesis inhibitor on delayed neuronal death induced by transient global ischemia in rat brain
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Ko JS, Bae CS, Kim JK
- KMID: 1849835
- Korean J Physiol Pharmacol.
- 1998 Jun;2(3):279-286.
It has been well documented that transient forebrain global ischemia causes selective neuronal degeneration in hippocampal CA1 pyramidal neurons with a delay of a few days. The mechanism of this delayed hippocampal CA1... -
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- A Neurodegenerative Hypothesis of Cytokine-Serotonin Interaction in Major Depression
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Kim YK
- KMID: 2341023
- J Korean Neuropsychiatr Assoc.
- 2004 Jul;43(4):386-392.
A growing body of evidence suggests that major depression is associated with increased productions of pro-inflammatory cytokines such as IL-1, IL-6, IL-12 or TNF-alpha and increased concentrations of prostaglandin E2... -
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- Values of Cytokines and Tryptophan Metabolites over a 12 Weeks Time Course in Patients with Depression and Somatoform Disorder
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Krause D, Kirnich VB, Stapf TM, Hennings A, Riemer S, Riedel M, Schmidmaier R, Gil FP, Rief W, Schwarz MJ
- KMID: 2441631
- Clin Psychopharmacol Neurosci.
- 2019 Feb;17(1):34-42.
- doi: 10.9758/cpn.2019.17.1.34
OBJECTIVE: Previous studies have suggested alterations in the kynurenine pathway as a major link between cytokine and neurotransmitter abnormalities in psychiatric disorders. Most of these studies used a cross-sectional case-control... -
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- Cytokines and Depression
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Kim YK
- KMID: 2029206
- Korean J Biol Psychiatry.
- 2008 Aug;15(3):175-185.
Accumulating evidence has suggested the existence of reciprocal communication between immune, endocrine, and neurotransmitter system. Cytokine hypothesis of depression implies that increased pro-inflammatory cytokine such as -1, IL-6, IL-12, TNF-alpha,... -
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- Functional Connectivity Map of Retinal Ganglion Cells for Retinal Prosthesis
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Ye JH, Ryu SB, Kim KH, Goo YS
- KMID: 2285357
- Korean J Physiol Pharmacol.
- 2008 Dec;12(6):307-314.
- doi: 10.4196/kjpp.2008.12.6.307
Retinal prostheses are being developed to restore vision for the blind with retinal diseases such as retinitis pigmentosa (RP) or age-related macular degeneration (AMD). Among the many issues for prosthesis... -
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- High-Fat Diet and Voluntary Chronic Aerobic Exercise Recover Altered Levels of Aging-Related Tryptophan Metabolites along the Kynurenine Pathway
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Lee KJ, Jung KH, Cho JY, Lee ST, Kim HS, Shim JH, Lee SK, Kim M, Chu K
- KMID: 2383782
- Exp Neurobiol.
- 2017 Jun;26(3):132-140.
- doi: 10.5607/en.2017.26.3.132
Tryptophan metabolites regulate a variety of physiological processes, and their downstream metabolites enter the kynurenine pathway. Age-related changes of metabolites and activities of associated enzymes in this pathway are suggestable... -
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- Tryptophan Metabolites in Irritable Bowel Syndrome: An Overnight Time-course Study
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Burr RL, Gu H, Cain K, Djukovic D, Zhang X, Han C, Callan N, Raftery D, Heitkemper M
- KMID: 2460485
- J Neurogastroenterol Motil.
- 2019 Oct;25(4):551-562.
- doi: 10.5056/jnm19042
BACKGROUND/AIMS: Patients with irritable bowel syndrome (IBS) often report poor sleep quality. Whether poor sleep is associated with tryptophan (Trp) metabolites is unknown. We compared serum Trp metabolites in women... -
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