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Increased B Cell Understanding Puts Improved Vaccine Platforms Just Over the Horizon

Notario GR, Kwak K

In the face of an endlessly expanding repertoire of Ags, vaccines are constantly being tested, each more effective than the last. As viruses and other pathogens evolve to become more...
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Structural Insights for β-Lactam Antibiotics

Kim D, Kim S, Kwon Y, Kim Y, Park H, Kwak K, Lee H, Lee JH, Jang KM, Kim D, Lee SH, Kang LW

Antibiotic resistance has emerged as a global threat to modern healthcare systems and has nullified many commonly used antibiotics. β-Lactam antibiotics are among the most successful and occupy approximately two-thirds...
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Small Dose of Midazolam Added to Fentanyl-Ropivacaine for Patient Controlled Epidural Analgesia after Subtotal Gastrectomy

Kwak K, Kim S, Jeon Y, Suh J, Kim Y, Ha J, Lee S

  • KMID: 1741571
  • Anesth Pain Med.
  • 2008 Jan;3(1):22-26.
BACKGROUND: Midazolam has been reported to have a spinally mediated antinociceptive effect. In this randomized, double-blind study, we evaluated whether a small dose of midazolam added to fentanyl-ropivacaine mixture for...
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Systematic review and meta-analysis of cancer risks in relation to environmental waste incinerator emissions: a meta-analysis of case-control and cohort studies

Baek K, Park JT, Kwak K

OBJECTIVES: Various toxic substances can be generated from incinerators, exposing nearby residents, and epidemiological studies have shown wide variations in risk estimates for cancer risk in populations living close to...
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In Vitro Virucidal Effect of Povidone-Iodine Against SARS-CoV-2

Shin KR, Kwak K, Cui C, Bae JY, Hong W, Park MS

As of September 2020, SARS-CoV-2 has infected over 30 million people worldwide, and the death toll has now risen to 950,000. Given that Povidone-iodine (PVP-I) had consistently been showing the...
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A study of predictive factors that can consider surgical treatment when the imaging findings are non-diagnostic for diagnosis of pediatric appendicitis

Choi S, Kim Y, Jeong R, Lee KH, Yu W, Yoon Y, Kwak K, Chung SY

  • KMID: 2550069
  • J Korean Soc Emerg Med.
  • 2023 Dec;34(6):615-621.
Objective: This study examined the predictive factors to decide the surgical treatment for clinically suspected pediatric acute appendicitis with equivocal imaging findings. Methods: This study was conducted retrospectively on children who...
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Correlation between C-MYC and HER2 Amplification in Non-selected Breast Cancers

Ahn SK, Kwak K, Shin E, Kim H, Kim J, Park K, Han S

PURPOSE: c-myc and HER2 have been reported be amplified in 20% to 30% of clinical breast cancers and appears to be related with poor clinical outcome. The relationship between amplification...
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Prediction model of severity in patients with acute cholangitis in the emergency department using machine learning models

Yun J, Park M, Kim Y, Lee K, Jeong R, Yu W, Kwak K, Choi S

  • KMID: 2553261
  • J Korean Soc Emerg Med.
  • 2024 Feb;35(1):67-76.
Objective: The purpose of this study was to develop a machine learning-based model (eXtreme Gradient boost [XGBoost]) that can accurately predict the severity of acute cholangitis in patients. The model...
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Association between use of humidifier disinfectant and allergic rhinitis in Korean children: a cross-sectional study based on the eighth Panel Study on Korean Children (PSKC)

Koh TH, Park JT, Kwon D, Kwak K

BACKGROUND: Rhinitis was the most frequently diagnosed disorder among users of humidifier disinfectants (HDs). The aim of our study was to investigate on the relationship between allergic rhinitis (AR) and...
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Association between shift work and hyperhomocysteinemia in male workers

Kang D, Kang SK, Choi WJ, Lee SH, Lee JH, Kwak K

BACKGROUND: Shift work is associated with a higher risk of cardiovascular diseases. Here, we sought to assess the relationship between shift work and plasma homocysteine levels. Determining the correlations between...
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Feasibility of Concurrent Adjuvant Chemotherapy and Radiotherapy after Breast-conserving Surgery in Early Breast Cancer

Cho H, Kwak K, Kim J, Sohn SC, Park K, Han S

PURPOSE: The optimal sequence of chemotherapy (CT) and radiotherapy (RT) remains uncertain although both can reduce breast cancer recurrence after breast-conserving surgery (BCS). The current study was performed to evaluate...
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Partial Breast Irradiation Using Brachy-therapy after Breast Conserving Surgery

Kwak K, Kim J, Sohn S, Lee K, Kim J, Park K, Han S

PURPOSE: Whole breast irradiation (WBI) after breast conserving surgery (BCS) is the standard treatment modality for controlling ipsilateral local recurrence of breast cancer. However, the WBI needs 5 to 6...
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Association between depression and cardiovascular disease risk in general population of Korea: results from the Korea National Health and Nutrition Examination Survey, 2016

Song J, Koh TH, Park O, Kwon D, Kang S, Kwak K, Park JT

BACKGROUND: Depression is considered as a risk factor for cardiovascular disease (CVD) and associated with changes in individuals' health status that might influence CVD risk. However, most studies have scrutinized...
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