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Hyaline Vascular Castleman Disease Involving Renal Parenchyma and a Lymph Node: A Case Report

Kwon JH, Min SK, Shin MK, Lee YS, Lee YG, Ko YH

Castleman disease is a rare lymphoproliferative lesion that is predominantly found in the mediastinum. Retroperitoneal and pararenal localizations are very rare. We describe a 36-year-old man with a hyaline vascular...
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Urachal Mucinous Tumor of Uncertain Malignant Potential: A Case Report

Choi JW, Lee JH, Kim YS

Urachal mucinous tumor of uncertain malignant potential is very rare and is characterized by a multilocular cyst showing the proliferation of atypical mucin-secreting cells without stromal invasion. As in ovarian...
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CpG Island Hypermethylation in Gastric Carcinoma and Its Premalignant Lesions

Kang GH

Gastric cancers arise through a multistep process characterized by the progressive accumulation of molecular alterations in which genetic and epigenetic mechanisms have been implicated. Gastric cancer is one of the...
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The Ratio of Atypical Ductal Hyperplasia Foci to Core Numbers in Needle Biopsy: A Practical Index Predicting Breast Cancer in Subsequent Excision

Lee JJ, Lee HJ, Kang J, Jo JH, Gong G

BACKGROUND: Although core needle biopsy (CNB) is considered to be the standard technique for histological diagnosis of breast lesions, it is less reliable for diagnosing atypical ductal hyperplasia (ADH). We...
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Mimicry of Minute Pulmonary Meningothelial-like Nodules to Metastatic Deposits in a Patient with Infiltrating Lobular Carcinoma: A Case Report and Review of the Literature

Kfoury H, Arafah MA, Arafah MM, Alnassar S, Hajjar W

Minute pulmonary meningothelial-like nodules (MPMNs) are incidentally found lesions in lung resection specimens and autopsies. MPMNs have been associated with neoplastic and non-neoplastic pulmonary conditions and occasionally with extrapulmonary diseases....
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Adenocarcinoma with Intraductal Papillary Mucinous Neoplasm Arising in Jejunal Heterotopic Pancreas

Song JY, Han JY, Choi SK, Kim L, Choi SJ, Park IS, Chu YC, Kim KH, Kim JM

A 74-year-old man suffered from jejunal perforation and adhesion to sigmoid colon due to adenocarcinoma associated with intraductal papillary mucinous neoplasm (IPMN) arising in a jejunal heterotopic pancreas. The jejunal...
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Fine Needle Aspiration Cytology of Metastatic Adenocarcinoma of the Gingiva from the Lung: A Case Report

You TK, Kim SR, Park HS, Jang KY, Moon WS, Chung MJ, Lee DG, Kang MJ

Metastases of malignant tumors to the oral region from distant sites are uncommon. A 45-year-old man with painless gingival swelling was diagnosed with adenocarcinoma of the lung. On cytology, clusters...
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Interobserver Variability in Diagnosing High-Grade Neuroendocrine Carcinoma of the Lung and Comparing It with the Morphometric Analysis

Ha SY, Han J, Kim WS, Suh BS, Roh MS

BACKGROUND: Distinguishing small cell lung carcinoma (SCLC) and large cell neuroendocrine carcinoma (LCNEC) of the lung is difficult with little information about interobserver variability. METHODS: One hundred twenty-nine cases of resected...
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Nuclear Image Analysis Study of Neuroendocrine Tumors

Park M, Baek T, Baek J, Son H, Kang D, Kim J, Lee H

BACKGROUND: There is a subjective disagreement about nuclear chromatin in the field of pathology. Objective values of red, green, and blue (RGB) light intensities for nuclear chromatin can be obtained...
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Chemotherapy-Associated Hepatopathy in Korean Colorectal Cancer Liver Metastasis Patients: Oxaliplatin-Based Chemotherapy and Sinusoidal Injury

Nam SJ, Cho JY, Lee HS, Choe G, Jang JJ, Yoon YS, Han HS, Kim H

BACKGROUND: Although chemotherapy-related hepatic injury has been reported in colorectal cancer liver metastasis (CRLM) patients, the morphologic changes caused by chemotherapeutic agents and the effect of chemotherapy on postoperative outcome...
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A Soft Tissue Perineurioma and a Hybrid Tumor of Perineurioma and Schwannoma

Park JY, Park NJ, Kim SP, Kwon KY, Lee SS

Perineuriomas are composed of differentiated perineurial cells. Perineuriomas have been recently recognized by the immunoreactivity for epithelial membrane antigen (EMA). Microscopically, perineuriomas show proliferation of spindle cells with wavy nuclei...
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Metaplastic Thymoma: Report of 4 Cases

Kang G, Yoon N, Han J, Kim YE, Kim TS, Kim K

Metaplastic thymoma (MT), accepted in the World Health Organization 2004 scheme, is a circumscribed tumor of the thymus exhibiting biphasic morphology. We herein describe the clinicopathologic features of four MTs...
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Detection of Survivin and COX-2 in Thyroid Carcinoma: Anaplastic Carcinoma Shows Overexpression of Nuclear Survivin and Low COX-2 Expression

Kim YA, Chang M, Park YJ, Kim JE

BACKGROUND: Overexpression of survivin, a member of the inhibitors of apoptosis protein, has been reported in various carcinomas, and its interaction with cyclooxygenase 2 (COX-2) results in accelerated tumor progression....
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Clinicopathologic Features of Q Fever Patients with Acute Hepatitis

Lee M, Jang JJ, Kim YS, Lee SO, Choi SH, Kim SH, Yu E

BACKGROUND: Q fever caused by Coxiella burnetii presents with diverse clinical and pathological features including subclinical or cholestatic hepatitis. However, the pathological features of liver biopsies from patients with Q...
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Evaluation of Urine Cytology in Urothelial Carcinoma Patients: A Comparison of CellprepPlus(R) Liquid-Based Cytology and Conventional Smear

Son SM, Koo JH, Choi SY, Lee HC, Lee YM, Song HG, Hwang HK, Han HS, Yun SJ, Kim WJ, Kim EJ, Lee OJ

BACKGROUND: Urine cytology is an important test in the screening of urothlelial neoplasms. The conventional smear (CS) method of testing urine samples has a low sensitivity, approximately 50% result accuracy...
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Detection of BRAFV600E Mutations in Papillary Thyroid Carcinomas by Peptide Nucleic Acid Clamp Real-Time PCR: A Comparison with Direct Sequencing

Jeong D, Jeong Y, Lee S, Lee H, Lee W, Kim H, Park D, Park S, Mu W, Cho HD, Oh MH, Lee SS, Yang SH, Kim CJ

BACKGROUND: Papillary thyroid carcinoma (PTC) of the thyroid is the most common endocrine malignancy. High prevalence of an activating point mutation of BRAF gene, BRAFV600E, has been reported in PTC....
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TNF-alpha and TNF-beta Polymorphisms are Associated with Susceptibility to Osteoarthritis in a Korean Population

Han L, Song JH, Yoon JH, Park YG, Lee SW, Choi YJ, Nam SW, Lee JY, Park WS

BACKGROUND: The tumor necrosis factor (TNF) is believed to play an important role in the pathophysiology of osteoarthritis (OA). Evidence shows that genetic polymorphisms make substantial contributions to the etiology...
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Biologic Response to Carbonated Hydroxyapatite Associated with Orthopedic Device: Experimental Study in a Rabbit Model

Jebahi S, Saoudi M, Badraoui R, Rebai T, Oudadesse , Ellouz Z, Keskese H, El Feki A, El Feki H

BACKGROUND: Carbonated hydroxyapatite (CHA) and related calcium phosphates have been studied for many years as implant materials due to their similarity with the mineral phase of bone. The main limitation...
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