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Pulmonary Calciphylaxis Associated with Acute Respiratory and Renal Failure Due to Cryptogenic Hypercalcemia: An Autopsy Case Report

Kim NR, Seo JW, Lim YH, Ham HS, Huh W, Han J

  • KMID: 2012067
  • Korean J Pathol.
  • 2012 Dec;46(6):601-605.
Metastatic calcification is rare; it is found during autopsy in patients who underwent hemodialysis. Diffuse calcium precipitation of small and medium-sized cutaneous vessels, known as calciphylaxis, can result in progressive...
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Adenolipoma of the Skin Arising at Neck Region

Lee HS, Song YS

  • KMID: 2012064
  • Korean J Pathol.
  • 2012 Dec;46(6):587-589.
We report here a case of adenolipoma of the skin, an unusual variant of lipoma, arising on the neck. A 56-year-old man visited our hospital due to an anterior neck...
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Construction of High-Density Tissue Microarrays at Low Cost by Using Self-Made Manual Microarray Kits and Recipient Paraffin Blocks

Choi CH, Kim KH, Song JY, Choi SJ, Kim L, Park IS, Han JY, Kim JM, Chu YC

  • KMID: 2012060
  • Korean J Pathol.
  • 2012 Dec;46(6):562-568.
BACKGROUND: Advances of tissue microarray (TMA) technology have enabled simultaneous in situ analysis of biomarker expression in a large number of archived pathology specimens. However, the relatively high cost of...
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Novel Mutation in PRKAR1A in Carney Complex

Park KU, Kim HS, Lee SK, Jung WW, Park YK

  • KMID: 2012066
  • Korean J Pathol.
  • 2012 Dec;46(6):595-600.
A case of Carney complex in a Korean patient is presented. The patient had the characteristics of Carney complex including skin lesions, positive family history, and multiple myxomas including a...
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Expression of SIRT1 and DBC1 in Gastric Adenocarcinoma

Kang Y, Jung WY, Lee H, Lee E, Kim A, Kim BH

  • KMID: 2012052
  • Korean J Pathol.
  • 2012 Dec;46(6):523-531.
BACKGROUND: Sirtuin 1 (SIRT1) and deleted in breast cancer 1 (DBC1) are known as tumor suppressor or promoter genes. This may be due to their diverse functions and interaction with...
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Rosai-Dorfman Disease: Report of a Case Associated with IgG4-Related Sclerotic Lesions

Park BH, Son DH, Kim MH, Shim TS, Lee HJ, Huh J

  • KMID: 2012063
  • Korean J Pathol.
  • 2012 Dec;46(6):583-586.
We describe a rare case of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) associated with a six-year history of autoimmune pancreatitis, which was controlled by steroid treatment. The patient presented...
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Diagnostic Difficulties in Fine Needle Aspiration of Benign Salivary Glandular Lesions

Jo HJ, Ahn HJ, Jung S, Yoon HK

  • KMID: 2012061
  • Korean J Pathol.
  • 2012 Dec;46(6):569-575.
BACKGROUND: The diagnostic accuracy of fine needle aspiration cytology (FNAC) of salivary lesions is relatively high, but cytologic interpretation might be confusing if the sample is lacking typical cytologic features. METHODS:...
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Primary Mucinous Cystadenocarcinoma of the Breast: Cytologic Finding and Expression of MUC5 Are Different from Mucinous Carcinoma

Kim SE, Park JH, Hong S, Koo JS, Jeong J, Jung WH

  • KMID: 2012069
  • Korean J Pathol.
  • 2012 Dec;46(6):611-616.
Mucinous cystadenocarcinoma (MCA) in the breast is a rare neoplasm. There have been 13 cases of primary breast MCA reported. The MCA presents as a large, partially cystic mass in...
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The Definition of Minimal Extrathyroid Extension in Thyroid Pathology by Analyzing Sizable Intra- and Extrathyroid Blood Vessels

Jeon HM, Lim BJ, Chang HS, Hong S

  • KMID: 2012058
  • Korean J Pathol.
  • 2012 Dec;46(6):548-553.
BACKGROUND: To define the exact boundary of the intrathyroid and extrathyroid aspects of a gland when determining the extent of cancer invasion, we plan to clarify the definition of sizable...
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Cervical Lymphadenopathy Mimicking Angioimmunoblastic T-Cell Lymphoma after Dapsone-Induced Hypersensitivity Syndrome

Rim MY, Hong J, Yo I, Park H, Chung DH, Ahn JY, Park S, Park J, Kim YS, Lee JH

  • KMID: 2012068
  • Korean J Pathol.
  • 2012 Dec;46(6):606-610.
A 36-year-old woman presented with erythematous confluent macules on her whole body with fever and chills associated with jaundice after 8 months of dapsone therapy. Her symptoms had developed progressively,...
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Prognostic Relevance of the Expression of CA IX, GLUT-1, and VEGF in Ovarian Epithelial Cancers

Kim K, Park WY, Kim JY, Sol MY, Shin DH, Park DY, Lee CH, Lee JH, Choi KU

  • KMID: 2012054
  • Korean J Pathol.
  • 2012 Dec;46(6):532-540.
BACKGROUND: Tumor hypoxia is associated with malignant progression and treatment resistance. Hypoxia-related factors, such as carbonic anhydrase IX (CA IX), glucose transporter-1 (GLUT-1), and vascular endothelial growth factor (VEGF) permit...
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Fine-Needle Aspiration Cytology of Pleomorphic Carcinomas of the Lung

Choi HS, Seol H, Heo IY, Jung CW, Cho SY, Park S, Koh JS, Lee SS

  • KMID: 2012062
  • Korean J Pathol.
  • 2012 Dec;46(6):576-582.
BACKGROUND: Pleomorphic carcinoma (PC) is a rare pulmonary malignancy. Because of its rarity and histological heterogeneity, cytopathologists might suspect PC only rarely on the basis of its cytological specimen. In...
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Clear Cell Papillary Renal Cell Carcinoma: A Report of 15 Cases Including Three Cases of Concurrent Other-Type Renal Cell Carcinomas

Park JH, Lee C, Suh JH, Moon KC

  • KMID: 2012056
  • Korean J Pathol.
  • 2012 Dec;46(6):541-547.
BACKGROUND: Clear cell papillary renal cell carcinoma (CCPRCC) is a recently established subtype of renal epithelial tumor. The aim of this study was to identify the diagnostic criteria of CCPRCC...
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Expression of c-Met Is Different along the Location and Associated with Lymph Node Metastasis of Head and Neck Carcinoma

Choe JY, Yun JY, Nam SJ, Kim JE

  • KMID: 2012050
  • Korean J Pathol.
  • 2012 Dec;46(6):515-522.
BACKGROUND: Activation of the c-Met pathway is involved in cancer progression and the prognosis. We aimed to identify any association of c-Met protein expression with a number of clinicopathologic variables...
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Multiple Jejunal Myeloid Sarcomas Presenting with Intestinal Obstruction in a Non-leukemic Patient: A Case Report with Ultrastructural Observations

Kim NR, Lee WK, Lee JI, Cho HY

  • KMID: 2012065
  • Korean J Pathol.
  • 2012 Dec;46(6):590-594.
Myeloid sarcoma is a rare extramedullary myeloid tumor, which is frequently misdiagnosed when no evidence of leukemia is initially observed. Here, we report on a peculiar case of a 49-year-old...
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Methylation and Immunoexpression of p16INK4a Tumor Suppressor Gene in Primary Breast Cancer Tissue and Their Quantitative p16INK4a Hypermethylation in Plasma by Real-Time PCR

Lee JJ, Ko E, Cho J, Park HY, Lee JE, Nam SJ, Kim DH, Cho EY

  • KMID: 2012059
  • Korean J Pathol.
  • 2012 Dec;46(6):554-561.
BACKGROUND: The p16INK4a gene methylation has been reported to be a major tumorigenic mechanism. METHODS: We evaluated the methylation status of the p16INK4a genes in 231 invasive breast cancer and 90...
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