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Prevalence and Clinical Characteristics of Aspirin Resistance in the Patients with Type 2 Diabetes

Kim SY

No abstract available.
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The Plasma Adiponectin Levels in Patients with Newly Diagnosed Type 2 Diabetes

Lee IS, Ku BJ, Kim YK

No abstract available.
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Non-alcoholic Fatty Liver Disease and Adiponectin

Choi KM

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The Biochemical Markers of Coronary Heart Disease Correlates Better to Metabolic Syndrome Defined by WHO than by NCEP-ATP III or IDF in Korean Type 2 Diabetic Patients

Lim DM, Park KY, Koh GP

BACKGROUND: Metabolic syndrome (MetS) is constellation of cardiovascular risk factors. There are three typically used definitions of MetS proposed by WHO, IDF and NCEP-ATP III. We conducted this study to...
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Clinical Implication of Adiponectin

Lim S, Jang HC

Adipose tissue is now considered as an active hormone-secreting organ, which secretes a number of biologically active adipokines such as free fatty acids, leptin, tumor necrosis factor alpha (TNFalpha), interleukin-6,...
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Association of Adiponectin and Hepatic Steatosis in Adults with Normal Transaminase Levels

Mun JH, Lee SE, Ahn JH, Shinn SH

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is associated with metabolic syndrome including insulin resistance, hypertension, dyslipidemia, central obesity, type 2 diabetes, and cardiovascular disease. In NAFLD, insulin resistance plays an...
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Clinical Characteristics and Outcomes of Diabetic Ketoacidosis at a Single Institution

Lee JI, Sohn TS, Chang SA, Lee JM, Cha BY, Son HY, Son HS

AIMS: The aim of this study was to describe the clinical characteristics and outcomes of diabetic ketoacidosis (DKA) in Hospital for past 6 years. METHODS: We reviewed the retrospective medical records...
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The Protective Effect of EGCG on INS-1 Cell in the Oxidative Stress and Mechanism

Kim MK, Jung HS, Yoon CS, Kwon MJ, Koh KS, Rhee BD, Park JH

BACKGROUND: Oxidative stress is important in both diabetic complications and the development and the progression of type 2 diabetes via the effects on the pancreatic beta-cells. EGCG (epigallocatechin galleate), a...
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Cloning of Novel Epidermal Growth Factor (EGF) Plasmid for Gene Therapy on Diabetic Foot Ulcer

Chung HS, Yoon CS, Kwon MJ, Kim MK, Lee SH, Ko KS, Rhee BD, Park JH

BACKGROUND: Epidermal Growth Factor (EGF) is one of the important growth factors involved in the epithelialization during cutaneous wound healing. Peptide EGF has been used for the treatment of diabetic...
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The Effect of Chronic High Glucose Concentration on Endoplasmic Reticulum Stress in INS-1 Cells

Kim MK, Seo HY, Yun TS, Kim NK, Hah YJ, Kim YJ, Cho HC, Jang YY, Kim HS, Ryu SY, Lee IK, Park KG

BACKGROUND: The highly developed endoplasmic reticulum (ER) structure is one of the characteristic features of pancreatic beta-cells. Recent study showed that ER stress causes beta-cell dysfunction. However, little is known...
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Rosiglitazone Activates AMPK and Improves Non-Alcoholic Fatty Liver Disease in OLETF Rats

Cho EH, Lee KU

BACKGROUND: Insulin resistance is very common in patients with nonalcoholic fatty liver disease (NAFLD). Glitazones improve insulin sensitivity by acting as a selective agonist of the peroxisome proliferators -activated receptor...
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The Effects of Exendin-4 on IRS-2 Expression and Phosphorylation in INS-1 Cells

Kim JH, Kim JW, Jeon SY, Park HS, Ham DS, You YH, Lee SH, Cho JH, Kang MJ, Lee KW, Kwon HS, Yoon KH, Cha BY, Lee KW, Kang SK, Son HY

BACKGROUND: Insulin receptor substrate 2 (IRS-2) is a key regulator of beta cell proliferation and apoptosis. This study was aimed to investigate effect of the glucolipotoxicity on apoptosis in INS-1...
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