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Patterns of Locoregional Recurrence after Radical Cystectomy for Stage T3-4 Bladder Cancer: A Radiation Oncologist’s Point of View

Kim HJ, Chun J, Kim TH, Yang G, Shin SJ, Kim JS, Yang J, Ham WS, Koom WS

Purpose: Adjuvant radiotherapy (RT) has been performed to reduce locoregional failure (LRF) following radical cystectomy for locally advanced bladder cancer; however, its efficacy has not been well established. We analyzed...
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Physical and Biological Characteristics of Particle Therapy for Oncologists

Byun HK, Han MC, Yang K, Kim JS, Yoo GS, Koom WS, Kim YB

Particle therapy is a promising and evolving modality of radiotherapy that can be used to treat tumors that are radioresistant to conventional photon beam radiotherapy. It has unique biological and...
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Clinical Outcomes of Immune Checkpoint Blocker Therapy for Malignant Melanoma in Korean Patients: Potential Clinical Implications for a Combination Strategy Involving Radiotherapy

Lee J, Chang JS, Roh MR, Jung M, Lee CK, Oh BH, Chung KY, Koom WS, Shin SJ

Purpose We investigated the clinical efficacy of immune checkpoint blocker (ICB) therapy for metastatic or advanced melanoma in Korean patients. As well, we assessed whether the effects of ICBs can be...
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A Survey of Radiation Therapy Utilization in Korea from 2010 to 2016: Focusing on Use of Intensity-Modulated Radiation Therapy

Rim CH, Lee J, Kim WC, Yang D, Yoon WS, Koom WS, Kim CY

BACKGROUND: This study aimed to assess the recent changes of radiation therapy (RT) modalities in Korea. In particular, we focused on intensity-modulated radiation therapy (IMRT) utilization as the main index,...
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Efficacy of Postoperative Radiotherapy Using Modern Techniques in Patients with Retroperitoneal Soft Tissue Sarcoma

Kim HJ, Koom WS, Cho J, Kim HS, Suh CO

PURPOSE: Local recurrence is the most common cause of failure in retroperitoneal soft tissue sarcoma patients after surgical resection. Postoperative radiotherapy (PORT) is infrequently used due to its high complication...
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Patterns of Care for Radiotherapy in the Neoadjuvant and Adjuvant Treatment of Gastric Cancer: A Twelve-Year Nationwide Cohort Study in Korea

Chang JS, Choi Y, Shin J, Kim KH, Keum KC, Kim HS, Koom WS, Park EC

PURPOSE: Although Korea has the highest incidence of gastric cancer worldwide and D2-lymphadenectomies are routinely performed, radiotherapy (RT) practice patterns have not been well studied. Therefore, we examined RT usage...
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Gold nanoparticles enhance anti-tumor effect of radiotherapy to hypoxic tumor

Kim MS, Lee EJ, Kim JW, Chung US, Koh WG, Keum KC, Koom WS

PURPOSE: Hypoxia can impair the therapeutic efficacy of radiotherapy (RT). Therefore, a new strategy is necessary for enhancing the response to RT. In this study, we investigated whether the combination...
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Variation in Practice Patterns of Korean Radiation Oncologists for Spine Metastasis between 2009 and 2014

Yu JI, Park HC, Ahn YC, Chung Y, Koom WS, Song SY

PURPOSE: The Korean Society of Radiation Oncologists (KOSRO) conducted the Patterns of Care Study (PCS) of radiotherapy (RT) for spine metastases in 2009. The current study was conducted to investigate...
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Art therapy using famous painting appreciation maintains fatigue levels during radiotherapy in cancer patients

Koom WS, Choi MY, Lee J, Park EJ, Kim JH, Kim SH, Kim YB

PURPOSE: The purpose of this study was to evaluate the efficacy of art therapy to control fatigue in cancer patients during course of radiotherapy and its impact on quality of...
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Treatment outcome of radiation therapy and concurrent targeted molecular therapy in spinal metastasis from renal cell carcinoma

Park S, Kim KH, Rhee WJ, Lee J, Cho Y, Koom WS

PURPOSE: To evaluate the clinical outcomes of patients who underwent radiation therapy with or without targeted molecular therapy for the treatment of spinal metastasis from renal cell carcinoma (RCC). MATERIALS AND...
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Morphologic change of rectosigmoid colon using belly board and distended bladder protocol

Cho Y, Chang JS, Kim MS, Lee J, Byun H, Kim N, Park SJ, Keum KC, Koom WS

PURPOSE: This study investigates morphologic change of the rectosigmoid colon using a belly board in prone position and distended bladder in patients with rectal cancer. We evaluate the possibility of...
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Outcome of Local Excision Following Preoperative Chemoradiotherapy for Clinically T2 Distal Rectal Cancer: A Multicenter Retrospective Study (KROG 12-06)

Noh JM, Park W, Kim JS, Koom WS, Kim JH, Choi DH, Park HC

  • KMID: 2167689
  • Cancer Res Treat.
  • 2014 Jul;46(3):243-249.
PURPOSE: The aim of this study was to examine the clinical implications of a pathologically complete response after neoadjuvant chemoradiotherapy (CRT) followed by local excision for patients with cT2 rectal...
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Vertebral compression fractures after spine irradiation using conventional fractionation in patients with metastatic colorectal cancer

Rhee WJ, Kim KH, Chang JS, Kim HJ, Choi S, Koom WS

PURPOSE: To evaluate the risk of vertebral compression fracture (VCF) after conventional radiotherapy (RT) for colorectal cancer (CRC) with spine metastasis and to identify risk factors for VCF in metastatic...
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The location of locoregional recurrence in pathologic T3N0, non-irradiated lower rectal cancer

Kim MS, Keum KC, Rhee WJ, Kim H, Kim M, Choi S, Nam KC, Koom WS

PURPOSE: To investigate the patterns of locoregional recurrence of pathologic T3N0 (pT3N0) lower rectal cancer omitting postoperative radiotherapy (RT) and explore the potential of modification of a RT field. MATERIALS AND...
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Risk stratification of abdominopelvic failure for FIGO stage III epithelial ovarian cancer patients: implications for adjuvant radiotherapy

Chang JS, Koom WS, Kim SW, Kim S, Kim YB, Kim YT, Kim GE

OBJECTIVE: To analyze patterns of abdominopelvic failures and to define subgroups for the use of adjuvant radiotherapy in the International Federation of Gynecology and Obstetrics (FIGO) stage III epithelial ovarian...
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Bladder filling variations during concurrent chemotherapy and pelvic radiotherapy in rectal cancer patients: early experience of bladder volume assessment using ultrasound scanner

Chang JS, Yoon HI, Cha HJ, Chung Y, Cho Y, Keum KC, Koom WS

PURPOSE: To describe the early experience of analyzing variations and time trends in bladder volume of the rectal cancer patients who received bladder ultrasound scan. MATERIALS AND METHODS: We identified 20...
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Chemoradiotherapy in squamous cell carcinoma of the anal canal: a single institution experience

Kim KH, Chang JS, Keum KC, Ahn JB, Lee CG, Koom WS

PURPOSE: We reviewed the treatment outcomes and prognostic factors for patients with anal canal carcinoma who were treated with curative intent chemoradiotherapy (CRT) at Severance Hospital from 2005 to 2011. MATERIALS...
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Nutritional status of patients treated with radiotherapy as determined by subjective global assessment

Koom WS, Ahn SD, Song SY, Lee CG, Moon SH, Chie EK, Jang HS, Oh YT, Lee HS, Keum KC

  • KMID: 2316710
  • Radiat Oncol J.
  • 2012 Sep;30(3):132-139.
PURPOSE: The purpose of this prospective multi-institutional study was to evaluate the nutritional status of patients undergoing radiotherapy (RT) for treatment of head and neck, lung, or gastrointestinal cancer. MATERIALS AND...
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Re-irradiation of recurrent esophageal cancer after primary definitive radiotherapy

Kim YS, Lee CG, Kim KH, Kim T, Lee J, Cho Y, Koom WS

  • KMID: 2316717
  • Radiat Oncol J.
  • 2012 Dec;30(4):182-188.
PURPOSE: For recurrent esophageal cancer after primary definitive radiotherapy, no general treatment guidelines are available. We evaluated the toxicities and clinical outcomes of re-irradiation (re-RT) for recurrent esophageal cancer. MATERIALS AND...
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Quantitative Assessment of Tumor Responses after Radiation Therapy in a DLD-1 Colon Cancer Mouse Model Using Serial Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Ahn SJ, Koom WS, An CS, Lim JS, Lee SK, Suh JS, Song HT

PURPOSE: The purpose of this study was to investigate the predictability of pretreatment values including Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) derived parameters (Ktrans, Kep and Ve), early changes in...
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