- Possible Therapeutic Effect of Exercise for Incurable Diseases
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Ko IG
- KMID: 2522741
- Int Neurourol J.
- 2021 Nov;25(Suppl 2):S45-46.
- doi: 10.5213/inj.2121edi.005
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- Therapeutic Strategies Against Apoptosis and Gliosis
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Ko IG
- KMID: 2510829
- Int Neurourol J.
- 2020 Nov;24(Suppl 2):65-66.
- doi: 10.5213/inj.2020edi.006
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- Applications of Basic Experimental and Clinical Research Using Biomarkers
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Ko IG
- KMID: 2431862
- Int Neurourol J.
- 2018 Dec;22(4):226-227.
- doi: 10.5213/inj.1820edi.010
No abstract available. -
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- Voluntary Wheel Running Improves Spatial Learning Memory by Suppressing Inflammation and Apoptosis via Inactivation of Nuclear Factor Kappa B in Brain Inflammation Rats
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Ko YJ, Ko IG
- KMID: 2510834
- Int Neurourol J.
- 2020 Nov;24(Suppl 2):96-103.
- doi: 10.5213/inj.2040432.216
Purpose: Exercise has been shown to protect against diverse brain diseases. Voluntary exercise improves cognition and has a neuroprotective effect. The aim of this investigation is to study the effect... -
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- Voluntary Wheel Running Exercise Improves Aging-Induced Sarcopenia via Activation of Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1α/Fibronectin Type III Domain-Containing Protein 5/Adenosine Monophosphate-Activated Protein Kinase Signaling Pathway
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Ko YJ, Ko IG
- KMID: 2516590
- Int Neurourol J.
- 2021 May;25(Suppl 1):S27-34.
- doi: 10.5213/inj.2142170.085
Purpose: In this study, the protective effect of voluntary wheel running exercise on muscle loss and muscle weakness in gastrocnemius of old rats was investigated. The association of voluntary wheel... -
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- Circadian Rhythms in Urinary Functions: Possible Roles of Circadian Clocks?
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Noh JY, Han DH, Yoon JA, Kim MH, Kim SE, Ko IG, Kim KH, Kim CJ, Cho S
- KMID: 2232796
- Int Neurourol J.
- 2011 Jun;15(2):64-73.
Circadian clocks are the endogenous oscillators that harmonize a variety of physiological processes within the body. Although many urinary functions exhibit clear daily or circadian variation in diurnal humans and... -
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- Protective Effect of Catechin on Apoptosis of the Lens Epithelium in Rats with N-methyl-N-nitrosourea-induced Cataracts
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Lee SM, Ko IG, Kim SE, Kim DH, Kang BN
- KMID: 946002
- Korean J Ophthalmol.
- 2010 Apr;24(2):101-107.
- doi: 10.3341/kjo.2010.24.2.101
PURPOSE: To investigate the effect of catechin on apoptotic cell death in the lens epithelium of rats with cataract. METHODS: Cataract was induced by intraperitoneal injection of 100 mg/kg N-methyl-N-nitrosourea... -
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- Resistance Exercise Improves Spatial Learning Ability Through Phosphorylation of 5’-Adenosine Monophosphate-Activated Protein Kinase in Parkinson Disease Mice
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Kim SH, Hwang L, Jin JJ, Ko IG, Kim YB, Yoon HS, Baek SS
- KMID: 2522743
- Int Neurourol J.
- 2021 Nov;25(Suppl 2):S55-62.
- doi: 10.5213/inj.2142336.168
Purpose: Exercise is a representative noninvasive treatment that can be applied to various diseases. We studied the effect of resistance exercise on motor function and spatial learning ability in Parkinson... -
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- Splenectomy affects the balance between hepatic growth factor and transforming growth factor-beta and its effect on liver regeneration is dependent on the amount of liver resection in rats
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Kim J, Kim CJ, Ko IG, Joo SH, Ahn HJ
- KMID: 1820072
- J Korean Surg Soc.
- 2012 Apr;82(4):238-245.
- doi: 10.4174/jkss.2012.82.4.238
PURPOSE: Small-for-size syndrome (SFSS) is a major problem in liver surgery, and splenectomy has been used to prevent SFSS. However, it is unknown whether splenectomy has the same effect on... -
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- Vardenafil Increases Cell Proliferation in the Dentate Gyrus through Enhancement of Serotonin Expression in the Rat Dorsal Raphe
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Kim TS, Ko IG, Sung YH, Kim SE, Kim BK, Park SK, Shin MS, Kim CJ, Yoon SJ, Kim KH
- KMID: 1783139
- J Korean Med Sci.
- 2009 Dec;24(6):1099-1104.
- doi: 10.3346/jkms.2009.24.6.1099
This study was conducted to evaluate the effects of vardenafil (Levitra), a phosphodiesterase-5 (PDE-5) inhibitor, on cell proliferation in the hippocampal dentate gyrus and on 5-hyroxytryptamine (5-HT, serotonin) synthesis and... -
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- Dexmedetomidine Ameliorates Sleep Deprivation-Induced Depressive Behaviors in Mice
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Moon EJ, Ko IG, Kim SE, Jin JJ, Hwang L, Kim CJ, An H, Lee BJ, Yi JW
- KMID: 2426692
- Int Neurourol J.
- 2018 Oct;22(Suppl 3):S139-S146.
- doi: 10.5213/inj.1836228.114
PURPOSE: Sleep deprivation induces depressive symptoms. Dexmedetomidine is a α2-adrenoreceptor agonist and this drug possesses sedative, anxiolytic, analgesic, and anesthetic-sparing effect. In this study, the action of dexmedetomidine on sleep... -
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- Pentoxifylline Alleviates Perinatal Hypoxic-Ischemia-Induced Short-term Memory Impairment by Suppressing Apoptosis in the Hippocampus of Rat Pups
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Park JH, Kim SE, Jin JJ, Choi HS, Kim CJ, Ko IG
- KMID: 2365741
- Int Neurourol J.
- 2016 Jun;20(2):107-113.
- doi: 10.5213/inj.1632532.266
PURPOSE: Perinatal hypoxic-ischemic brain damage is a major cause of acute mortality and chronic neurologic morbidity in infants and children. We investigated the effects of pentoxifylline, a methylxanthine derivative and... -
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- Polydeoxyribonucleotide Attenuates Airway Inflammation Through A2AR Signaling Pathway in PM10-Exposed Mice
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Hwang L, Jin JJ, Ko IG, Kim S, Cho YA, Sung JS, Choi CW, Chang BS
- KMID: 2516589
- Int Neurourol J.
- 2021 May;25(Suppl 1):S19-26.
- doi: 10.5213/inj.2142168.084
Purpose: Inhalation of air containing high amounts of particular matter (PM) causes various respiratory disorders including asthma, chronic obstructive pulmonary disease, and lung cancer. The changes of expression of inflammatory... -
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- Combination Therapy With Polydeoxyribonucleotide and Pirfenidone Alleviates Symptoms of Acute Respiratory Distress Syndrome in Human Lung Epithelial A549 Cells
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Hwang JJ, Ko IG, Jin JJ, Hwang L, Kim SH, Jeon JW, Paik SS, Chang BS, Choi CW
- KMID: 2501361
- Int Neurourol J.
- 2020 May;24(Suppl 1):S56-64.
- doi: 10.5213/inj.2040152.076
Purpose: Acute respiratory distress syndrome (ARDS) is characterized by its acute onset of symptoms such as bilateral pulmonary infiltrates, severe hypoxemia, and pulmonary edema. Many patients with ARDS survive in... -
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- Effect of Long-term Exercise on Voiding Functions in Obese Elderly Women
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Ko IG, Lim MH, Choi PB, Kim KH, Jee YS
- KMID: 2232887
- Int Neurourol J.
- 2013 Sep;17(3):130-138.
PURPOSE: An overactive bladder (OAB) may be defined as urgency that is a sudden, compelling, difficult to defer desire to pass urine that is usually accompanied by frequency and nocturia... -
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- Long-term Surgical and Chemical Castration Deteriorates Memory Function Through Downregulation of PKA/CREB/BDNF and c-Raf/MEK/ERK Pathways in Hippocampus
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Shin MS, Kim TW, Park SS, Ko IG, Kim CJ, Kim M, Roh SY, Kim KT, Kim KH
- KMID: 2452559
- Int Neurourol J.
- 2019 Jun;23(2):116-124.
- doi: 10.5213/inj.1938103.052
PURPOSE: Goserelin is a drug used for chemical castration. In a rat model, we investigated whether surgical and chemical castration affected memory ability through the protein kinase A (PKA)/cyclic adenosine... -
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- Swimming Exercise Ameliorates Symptoms of MOG-Induced Experimental Autoimmune Encephalomyelitis by Inhibiting Inflammation and Demyelination in Rats
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Kim JY, Yi ES, Lee H, Kim JS, Jee YS, Kim SE, Kim CJ, Ko IG
- KMID: 2501359
- Int Neurourol J.
- 2020 May;24(Suppl 1):S39-47.
- doi: 10.5213/inj.2040156.078
Purpose: Multiple sclerosis is an autoimmune disease that affects the central nerve system, resulting in cumulative loss of motor function. Multiple sclerosis is induced through multiple mechanisms and is caused... -
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- Polydeoxyribonucleotide Ameliorates Inflammation and Apoptosis in Achilles Tendon-Injury Rats
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Rho JH, Ko IG, Jin JJ, Hwang L, Kim SH, Chung JY, Hwang TJ, Han JH
- KMID: 2510832
- Int Neurourol J.
- 2020 Nov;24(Suppl 2):79-87.
- doi: 10.5213/inj.2040428.214
Purpose: Adenosine A2A receptor agonist polydeoxyribonucleotide (PDRN) possesses an anti-inflammatory effect and suppress apoptotic cell death in several disorders. In this current study, the effect of PDRN on inflammation and... -
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- Presence of multiple peripheral circadian oscillators in the tissues controlling voiding function in mice
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Noh JY, Han DH, Kim MH, Ko IG, Kim SE, Park N, Choe HK, Kim KH, Kim K, Kim CJ, Cho S
- KMID: 2155346
- Exp Mol Med.
- 2014 Mar;46(3):e81.
- doi: 10.1038/emm.2013.153
Circadian clocks are the endogenous oscillators that harmonize a variety of physiological processes within the body. Although many urinary functions exhibit clear daily or circadian variation in diurnal humans and... -
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- Vardenafil Enhances Oxytocin Expression in the Paraventricular Nucleus without Sexual Stimulation
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Shin MS, Ko IG, Sung YH, Kim SE, Kim BK, Kim CJ, Lee SW, Kim DH, Chang JH, Kim KH
- KMID: 2232770
- Int Neurourol J.
- 2010 Dec;14(4):213-219.
PURPOSE: Oxytocin is associated with the ability to form normal social attachments. c-Fos is an immediate early gene whose expression is used as a marker for stimulus-induced changes in neurons.... -
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