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A Report of Bone Marrow Metastasis of Colon Cancer as a Primary Diagnosis, Supported by Cytokeratin Immunohistochemical Staining

Kim B, Lee KT

Bone marrow metastasis of colon cancer is rare. Here, we report a 56-year-old female patient who presented with pancytopenia. She was diagnosed with colon cancer accompanied by lung and axial...
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Cytokeratin 20 negative Merkel cell carcinoma consistent with negative Merkel cell polyomavirus

Kwon O, Chung H, Park J

Merkel cell carcinoma (MCC) is a rare neuroendocrine tumor that is highly aggressive in nature and indolent in progression. The common risk factors for MCC are senility, prolonged exposure to...
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Cytokeratin 13, Cytokeratin 17, and Ki-67 Expression in Human Acquired Cholesteatoma and Their Correlation With Its Destructive Capacity

Hamed MA, Nakata S, Shiogama K, Suzuki K, Sayed RH, Nishimura , Iwata N, Sakurai K, Badawy BS, Inada K, Tsuge H, Tsutsumi Y

OBJECTIVES: Cholesteatoma is a nonneoplastic destructive lesion of the temporal bone with debated pathogenesis and bone resorptive mechanism. Both molecular and cellular events chiefly master its activity. Continued research is...
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The Detection of Messenger RNA for Carcinoembryonic Antigen and Cytokeratin 20 in Peritoneal Washing Fluid in Patients with Advanced Gastric Cancer

Kim YJ, Chung WC, Choi S, Jung YD, Lee J, Chae SY, Jun KH, Chin HM

BACKGROUND/AIMS: Peritoneal micrometastasis is known to play an important role in the recurrence of gastric cancer. However, its effects remain equivocal. Herein, we examine the messenger RNA (mRNA) as tumor...
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Diagnostic Utility of Serum Cytokeratin Fragment 21-1 in Patients with Lung Cancer

Song S, Yoo EH, Cho HJ

BACKGROUND: Lung cancer is the most lethal malignant neoplasm in the world. Serum cytokeratin fragment 21-1 (Cyfra 21-1) is a valuable tumor marker for detection of lung cancer, and it...
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Immunohistochemical study on cytokeratin expression on developing tongue in Korean native goats (Capra hircus)

Cho GH, Kim M, Kim CS, Kim GS, Won CK

Cytokeratin (CK) comprises the intermediate filament cytoskeleton of epithelial cells. Patterns of CK expression can be regarded as a specific marker for epithelial differentiation status. The aim of this study...
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The Significance of Caspase-Cleaved Cytokeratin 18 in Pleural Effusion

Lee KS, Chung JY, Jung YJ, Chung WY, Park JH, Sheen SS, Lee KB, Park KJ

  • KMID: 2320484
  • Tuberc Respir Dis.
  • 2014 Jan;76(1):15-22.
BACKGROUND: Apoptosis plays a role in the development of pleural effusion. Caspase-cleaved cytokeratin 18, a marker for epithelial cell apoptosis, was evaluated in pleural effusion. METHODS: A total of 79 patients...
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Expression of Cyclin D1, Cytokeratin 7, Cytokeratin 20 and Vimentin in Papillary Thyroid Cancer and Relationship with Patient's Prognostic Factors

Kim HJ, Kim YS, Kim SW, Kim KC

PURPOSE: Cyclin D1, cytokeratin(CK)7, CK20 and vimentin play an important role in tumorigenesis and tumor progression. Our aim was to investigate the expression of cyclin D1, CK7, CK20 and vimentin...
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Pseudometastasis in Sentinel Lymph Nodes with Cytokeratin Debris-containing Histiocytes in Breast Cancer Patient: A Case Report

Choi KH, Cha EJ, Choi HN, Moon WS

  • KMID: 1521620
  • Korean J Pathol.
  • 2007 Dec;41(6):427-429.
Immunohistochemical staining for cytokeratins can detect false negative nodes in patients with breast carcinoma. We report on a patient with breast carcinoma and pseudometastasis detected by immunohistochemical staining within a...
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The Expressions of Cytokeratin 16, Involucrin and PCNA in Clear Cell Acanthoma on Areola

Kim SY, Choi HY, Myung KB, Choi YW

  • KMID: 2302164
  • Korean J Dermatol.
  • 2007 Aug;45(8):804-810.
BACKGROUND: Clear cell acanthoma usually appears as an asymptomatic nodule on the leg. It has an unusual clinical feature in that it is presented as chronic eczema on the areola....
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Association between IgG Autoantibodies to Cytokeratin 18 Protein and Clinical Severity in Adult Asthmatic Patients

  • KMID: 2234388
  • Korean J Asthma Allergy Clin Immunol.
  • 2006 Sep;26(3):219-224.
BACKGROUND: Cytokeratin 18 (CK18) protein was identified as an airway epithelial cell antigen associated with nonallergic asthma. OBJECTIVE: We evaluated an association between IgG autoantibodies to CK18 protein and clinical severity...
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Usefulness of Galectin-3, Cytokeratin 19, p53, and Ki-67 for the Differential Diagnosis of Thyroid Tumors

Park MI, Kang DY

  • KMID: 2277677
  • Korean J Pathol.
  • 2006 Apr;40(2):86-92.
BACKGROUND: The expressions of galectin-3, cytokeratin 19, p53, and Ki-67 in papillary carcinoma (PC), follicular carcinoma (FC), follicular adenoma (FA), and nodular hyperplasia (NH) are characteristic for the differential diagnosis...
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Clinical Usefulness of Cytokeratin 7 and 20 Expression in Metastatic Ovarian Tumors

Cho YH, Kim KR, Kim TY, Kim JH, Suh DS, Kim YM, Nam JH, Mok JE, Kim YT

  • KMID: 2013152
  • Korean J Obstet Gynecol.
  • 2006 Mar;49(3):580-591.
OBJECTIVE: To investigate the pattern of Cytokeratin (CK) 7 and 20 expression and evaluate its clinical usefulness in the differential diagnosis of metastatic ovarian carcinoma. METHODS: One hundred eighty nine cases...
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Expressions of p53, Ki-67, PCNA and cytokeratin 17, cytokeratin 18 in recurred and non-recurred ameloblastoma

Hong JU, Shin SH

  • KMID: 1575589
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2005 Nov;27(6):501-509.
Ameloblastoma is a common odontogenic benign tumor of the jaw bone. However, it might be albe to infiltrate into the adjacent tissue, causing bony destruction and high recurrent rate....
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Expression of cytokeratin subtypes and vimentin in ameloblastoma

Kang MS, Yoon HK, Kim WH, Choi SI

  • KMID: 1575788
  • J Korean Assoc Oral Maxillofac Surg.
  • 2005 Aug;31(4):316-321.
Ameloblastoma is the most common odontogenic tumor of the jawbones, but the origin of this tumor has been remained to be unproven. Cytokeratins (CKs) are specific intermediate filament of epithelial...
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Prognostic Value of Bone Marrow Micrometastasis Detected by Nested RT-PCR for Cytokeratin 19 and Mammaglobin in Breast Cancer

Jung YS, Lee SL, Jeong IH, Yoon TI, Ahn SI, Park HB, Yim HE, Kim HJ, Soh EY, Kim MW

  • KMID: 1844415
  • J Korean Surg Soc.
  • 2005 Jun;68(6):449-456.
PURPOSE: Breast cancers frequently undergo distant metastasis during the early phase, on which the survival of patients is greatly dependent. It has been suggested that the occurrence of micrometastasis relates...
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Diagnosis of micrometastasis in lymph node and clinical evaluation of prognostic factor of oral SCC using RT-PCR and immunohistochemistry for cytokeratin

Park SJ, Lee WD, Lim KY, Kang JH, Myung H, Lee JH, Kim MJ

  • KMID: 1961054
  • J Korean Assoc Oral Maxillofac Surg.
  • 2005 Apr;31(2):105-115.
PURPOSE: The lymph node status assessed by conventional histological examination is the most important prognostic factor in patients undergoing surgery for oral squamous cell carcinoma. The presence of lymph node...
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Intraoperative Examination of Sentinel Lymph Nodes Using Rapid Cytokeratin Immunohistochemical Staining in Breast Cancer Patients

Lee IK, Jeong J, Chang HS, Park BW, Jung WH, Hong SW, Oh KK, Ryu YH, Lee HD

PURPOSE: Sentinel lymph node (SLN) biopsy has become a new standard procedure in the treatment of patients with early breast cancer. Furthermore, many institutions have begun offering the sentinel lymph...
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Relation of the radiologic findings and labeling index of Ki-67, PCNA and cytokeratin in unicystic ameloblastoma, dentigerous cyst and odontogenic keratocyst

Song MY, Lee SS, Lee JK, Yi WJ, Heo MS, Lee JI, Min BM, Choi SC

  • KMID: 1515548
  • Korean J Oral Maxillofac Radiol.
  • 2004 Jun;34(2):75-79.
PURPOSE: To compare the proliferation potential of the epithelial cells between unicystic ameloblastoma (UA), dentigerous cyst (DC), and odontogenic keratocyst (OKC) and to correlate this proliferation potential with the radiographic...
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Detection of Micrometastasis in Draining Vein before & after Manipulation and Peritoneal Cavity in Colorectal Cancer by Reverse Transcriptase-Polymerase Chain Reactions for Cytokeratin 20 and Carcinoembryonic Antigen

Joo JK, Lee JH, Park YK, Ryu SY, Kim DY, Kim YJ

  • KMID: 2325019
  • J Korean Surg Soc.
  • 2004 Mar;66(3):194-198.
PURPOSE: Micrometastasis is known as a significant predictor of prognosis in colorectal cancer patients. Recently, reverse transcriptase polymerase chain reaction (RT-PCR) has been applied to detecting micrometastasis. The drainage vein...
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