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Loss of EMP2 Inhibits Melanogenesis of MNT1 Melanoma Cells via Regulation of TRP-2

Enkhtaivan E, Kim HJ, Kim B, Byun HJ, Yu L, Nguyen TM, Nguyen TH, Do PA, Kim EJ, Kim KS, Huy HP, Rahman M, Jang JY, Rho SB, Lee H, Kang GJ, Park MK, Kim NH, Choi CI, Lee K, Han HK, Cho J, Lee AY, Lee CH

Melanogenesis is the production of melanin from tyrosine by a series of enzyme-catalyzed reactions, in which tyrosinase and DOPA oxidase play key roles. The melanin content in the skin determines...
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Dieckol, a Component of Ecklonia cava, Suppresses the Production of MDC/CCL22 via Down-Regulating STAT1 Pathway in Interferon-gamma Stimulated HaCaT Human Keratinocytes

Kang NJ, Koo DH, Kang GJ, Han SC, Lee BW, Koh YS, Hyun JW, Lee NH, Ko MH, Kang HK, Yoo ES

Macrophage-derived chemokine, C-C motif chemokine 22 (MDC/CCL22), is one of the inflammatory chemokines that controls the movement of monocytes, monocyte-derived dendritic cells, and natural killer cells. Serum and skin MDC/CCL22...
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Cardamonin Suppresses TGF-beta1-Induced Epithelial Mesenchymal Transition via Restoring Protein Phosphatase 2A Expression

Kim EJ, Kim HJ, Park MK, Kang GJ, Byun HJ, Lee H, Lee CH

Epithelial mesenchymal transition (EMT) is the first step in metastasis and implicated in the phenotype of cancer stem cells. Therefore, understanding and controlling EMT, are essential to the prevention and...
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12-O-Tetradecanoylphorbol-13-Acetate Induces Keratin 8 Phosphorylation and Reorganization via Expression of Transglutaminase-2

Lee EJ, Park MK, Kim HJ, Kang JH, Kim YR, Kang GJ, Byun HJ, Lee CH

  • KMID: 2170651
  • Biomol Ther.
  • 2014 Mar;22(2):122-128.
The stiffness of cancer cells is attributable to intermediate filaments such as keratin. Perinuclear reorganization via phosphorylation of specific serine residue in keratin is implicated in the deformability of metastatic...
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Anti-Inflammatory Effect of Quercetagetin, an Active Component of Immature Citrus unshiu, in HaCaT Human Keratinocytes

Kang GJ, Han SC, Ock JW, Kang HK, Yoo ES

  • KMID: 1502516
  • Biomol Ther.
  • 2013 Mar;21(2):138-145.
Citrus fruit contain various flavonoids that have multiple biological activities. However, the content of these flavonoids are changed during maturation and immature Citrus is known to contain larger amounts than...
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The Chloroform Fraction of Carpinus tschonoskii Leaves Inhibits the Production of Inflammatory Mediators in HaCaT Keratinocytes and RAW264.7 Macrophages

Kang GJ, Kang NJ, Han SC, Koo DH, Kang HK, Yoo BS, Yoo ES

  • KMID: 1432309
  • Toxicol Res.
  • 2012 Dec;28(4):255-262.
Inflammation is the immune system's response to infection and injury-related disorders, and is related to pro-inflammatory factors (NO, PGE2, cytokines, etc.) produced by inflammatory cells. Atopic dermatitis (AD) is a...
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External Application of Fermented Olive Flounder (Paralichthys olivaceus) Oil Alleviates Inflammatory Responses in 2,4-Dinitrochlorobenzene-induced Atopic Dermatitis Mouse Model

Han SC, Kang GJ, Ko YJ, Kang HK, Moon SW, Ann YS, Yoo ES

  • KMID: 2317802
  • Toxicol Res.
  • 2012 Sep;28(3):159-164.
Allergic skin inflammation such as atopic dermatitis (AD) is characterized by edema and infiltration with various inflammatory cells such as mast cells, basophils, eosinophils and T cells. Thymic stromal lymphopoietin...
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Self-Care, Symptom Experience, and Health-Related Quality of Life by COPD Severity

Kang GJ, Kim MH, Hwang SK

  • KMID: 2290707
  • J Korean Acad Adult Nurs.
  • 2008 Feb;20(1):163-175.
PURPOSE: This study aimed to define the relationship among self-care, symptom experiences, and health-related quality of life(HRQoL) according to the severity of disease in chronic obstructive pulmonary disease(COPD) patients. METHODS: The...
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Mitochondrial DNA 5178 C>A Polymorphism is Associated with Serum Lipid Levels

Kim HJ, Cho MY, Kim M, Park KC, Kang GJ, Jang CH, Kim YS, Lee KH, Park SK

  • KMID: 2008178
  • J Korean Diabetes Assoc.
  • 2004 Dec;28(6):501-510.
BACKGROUND: The mitochondrial DNA 5178 C>A polymorphism (Mt5178A) has been reported to the be associated with longevity, serum lipid levels and acute myocardial infarction in Japanese population. However, most of...
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Overexpression of Hepatocyte Growth Factor and c-Met as well as Angiogenesis in Endometrial Hyperplasia and Adenocarcinoma

Kang GJ, Sin BS, Jang SK, Yoon MS, Lee CH

  • KMID: 2270098
  • Korean J Obstet Gynecol.
  • 2001 Feb;44(2):355-363.
OBJECTIVE: This study was carried out to evaluate the clinicopathologic significance of hepatocyte growth factor (HGF) and c-met expression as well as tumor angiogenesis in endometrial hyperplasia and adenocarcinoma. METHOD: By...
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A case of uterine didelphys associated with ipsilateral renal agenesis, Gartner's duct cyst and uterine myoma

Kim HJ, Lee DH, Park JH, Yoon JS, Kang GJ, Yoon MS

  • KMID: 2036217
  • Korean J Obstet Gynecol.
  • 2000 Dec;43(12):2315-2318.
No abstract available.
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Two Cases of Presacral Teratomas in Adult

Shin BS, Bae EJ, Kang GJ, Yoon MS

  • KMID: 2262129
  • Korean J Obstet Gynecol.
  • 2000 Nov;43(11):2050-2054.
Teratomas are neoplasm composed of a wide variety of tissues foreign to the organs or anatomic sites in which they arise. They generally arise in gonads but a few cases...
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Clinical Study of the Pelvic Masses in Reproductive Ages

Yoon MS, Lee YA, Bae EJ, Kim GH, Kang GJ

  • KMID: 1568992
  • Korean J Obstet Gynecol.
  • 2000 Aug;43(8):1437-1443.
No abstract available.
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The Value of Squamous Cell Carcinoma Antigen as a Predictor of Nodal Metastasis in Cervical Cancer

Park CS, Ko HK, Kang GJ, Yoon MS, Sol MY

  • KMID: 2269979
  • Korean J Obstet Gynecol.
  • 2000 Mar;43(3):418-422.
OBJECTIVE: The clinical value of preoperative serum squamous cell carcinoma antigen(SCC) in relation to clinical stage, tumor volume, disease extent and prognosis has already reported in many papers. The aim...
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A Study on Expression Pattern of p53, Rb Gene and Apoptosis in Ovarian Epithelial Borderline Tumors and Invasive Carcinoma

Ha MW, Ko HK, Kang GJ, Yoon MS, Sol MY

  • KMID: 2269976
  • Korean J Obstet Gynecol.
  • 2000 Mar;43(3):407-413.
OBJECTIVE: The aim of this study is to evaluate the role of tumor suppressor genes, p53 and Rb gene, as well as apoptosis in the carcinogenesis of ovarian epithelial tumors....
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A Case of Primary Signet Ring Cell Carcinoma of the Uterine Cervix

Bae EJ, Ko HG, Ahn YD, Kang GJ, Yoon MS

  • KMID: 2261566
  • Korean J Obstet Gynecol.
  • 1999 Oct;42(10):2382-2385.
Signet ring cell adenocarcinoma of the cervix is most commonly considered to be metastatic in origin. We describe one case of primary signet ring cell adenocarcinoma of the cervix occurring...
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A Case of Benign Ovarian Steroid Cell Tumor with Huge Ascites and Elevated Serum CA125

Chae HJ, Yang SH, Ahn YD, Kim KH, Kang GJ

  • KMID: 1537015
  • Korean J Gynecol Oncol Colposc.
  • 1999 Sep;10(3):300-305.
Steroid cell tumor of ovary, first described as lipid cell tumor, is rare lesions composed entirely of cells resembling typical steroid hormone - secreting cells, that is lutein cells, Leydig...
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Therapeutic Conization of Microinvasive Carcinoma of the Uterine Cervix

Ahn YD, Yang SH, Chae HJ, Kang GJ, Yoon MS

  • KMID: 2269615
  • Korean J Obstet Gynecol.
  • 1999 May;42(5):1079-1084.
Microinvasive squamous cell carcinoma of the cervix is a subject associated with decades of confusion and multiplicity of definitions. And so the treatment of microinvasive squamous cell carcinoma...
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A Case of Pelvic Retroperitoneal Schwannoma : Preoperatively Suspected of Malignant Adnexal Tumor

Kang GJ, Hwang IS, Won S, Yoon MS

  • KMID: 2261181
  • Korean J Obstet Gynecol.
  • 1998 Sep;41(9):2480-2482.
Schwannoma is the most common type of peripheral nerve tumor, which arise from Schwann cell of nerve sheath, and most are amenable to surgical cure with minimal morbidity. The majority...
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A Case of Ovarian Cancer in Patient with Dermatomyositis

Won S, Kang GJ

  • KMID: 1890517
  • Korean J Gynecol Oncol Colposc.
  • 1998 Jun;9(2):174-177.
Dermatomyositis is a rare inflammatory condition of the skin and muscles which is believed to be a paraneoplastic syndrome. The annual incidence of dermatomyositis is 0.7~1/100,000 in the general population,...
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