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Modulatory Effects of Ginsenoside on the Regulation of KATP Channel Activity in Rat Myocardium

Ju JM, Lee YJ, Park JS, Kim JH

  • KMID: 2274946
  • Chonnam Med J.
  • 2002 Dec;38(4):307-314.
Modulatory effects of protopanaxadiol (PPD), a group of the extracted ginsenosides, on the regulation of ATP-sensitive potassium channel (KATP channel) activity were examined, using patch clamp technique, in isolated rat...
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Effects of PGI2 on the ATP-sensitive Potassium Channel Activity in the Isolated Rat Cardiac Myocytes

Ju JM, Choi DS, Piao LH, Kim JH

  • KMID: 1613959
  • Chonnam Med J.
  • 2003 Sep;39(3):162-170.
It was examined that the effects of PGI2 on the ATP-sensitive potassium channel (KATP channel) activity in the rat myocardium using patch clamp and action potential measurement techniques. PGI2, doses...
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The Usefulness of Chest and Abdominal CT in Detection of Thoracolumbar Spine Fracture after Multiple Blunt Trauma

Ju JM, Lim YS, Kim JK, Yang HJ, Lee G, Jin W, Hwang SY

  • KMID: 1998742
  • J Korean Soc Emerg Med.
  • 2003 Dec;14(5):646-652.
PURPOSE: To compare the accuracy of spine plain films with chest and abdominal Computed Tomography (CT) for trauma in detection of spine fractures. METHODS: Patients who sustained multiple blunt injury and...
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Effect of prostaglandins D2, E2 and I2 on the regulation of KATP channel activity in rat cardiac myocytes

Ju JM, Nah SY, Kim JH

  • KMID: 2071552
  • Korean J Physiol Pharmacol.
  • 1999 Oct;3(5):507-512.
Contribution of prostaglandins D2, E2 and I2 (PGD2, PGE2 and PGI2) on the regulation of ATP-sensitive K+ channel (KATP channel) was investigated in isolated single rat ventricular cardiac myocytes using the patch clamp...
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Kinetics of IFN-gamma and IL-17 Production by CD4 and CD8 T Cells during Acute Graft-versus-Host Disease

Ju JM, Lee H, Oh K, Lee DS, Choi EY

Graft-versus-host disease (GVHD) is a fatal complication that occurs after allogeneic hematopoietic stem cell transplantation. To understand the dynamics of CD4 and CD8 T cell production of IFN-gamma and IL-17...
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Selection of Thymocytes Expressing Transgenic TCR Specific for a Minor Histocompatibility Antigen, H60

Ju JM, Kim MB, Ryu SJ, Kim JY, Chang J, Choi EY

Minor histocompatibility antigens are MHC-bound peptides and contribute to the generation of allo-responses after allogeneic transplantation. H60 is a dominant minor H antigen that induces a strong CD8 T-cell response...
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Influence of Nitric Oxide Donor on the Regulation of ATP-sensitive K+ Channel Activity in Cardiac Myocytes

Ju JM, Shin DH, Lee WS, Park HW, Cho JG, Kim JH

  • KMID: 2116759
  • Chonnam Med J.
  • 2002 Jun;38(2):135-145.
It was investigated that effects of nitric oxide donors on the ATP-sensitive K+ channel (KATP channel) in isolated mouse ventricular cardiac myocytes using patch clamp techniques. In perforated whole-cell patches,...
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Influence of Ischemic-Simulation on the Action Potential Characteristics in Rat Atrial Fibers

Kim JH, Ju JM, Cho YB, Shin DH, Ahn BH, Joo SB, Kim SH

BACKGROUND: To investigate the mechanisms of myocardial ischemia induced changes of electrophysiological properties, influences of various ischemic-simulated Tyrode's solutions on the changes of action potential characteristics were examined. METHOD: Action...
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Role of alpha-Adrenergic Receptors in the Development of Delayed Afterdepolarization

Kim JH, Joo KC, Ju JM, Kook H, Shin DH, Cho JG

BACKGROUND: To investigate the role of alpha-adrenergic receptors in the development of delayed afterdepolarization, the effect of alpha-adrenoceptor stimulation and blockade on ouabain induced delayed afterdepolarization(DDAD) was examined in rabbit...
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Comparison of the Effects Elicited by Bromocriptine and SKF-38393 on Transmembrane Action Potential in Rat Atrial Fibers

Ju JM, Kim HH, Piao LH, Park HW, Cho JG, Kim JH

  • KMID: 1973359
  • Chonnam Med J.
  • 2004 Jun;40(2):61-70.
Effects of two dopaminergic agonists bromocriptine (BRO) and SKF-38393 (SKF) on electrophysiology of the ischemia-simulated rat atrial fibers with superfusion of modified physiologic salt solution (MPSS) were examined. All the...
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Attenuation of Hepatic Graft-versus-host Disease in Allogeneic Recipients of MyD88-deficient Donor Bone Marrow

Lim JY, Lee YK, Lee SE, Ju JM, Park G, Choi EY, Min CK

Acute graft-versus-host-disease (GVHD) is characterized by selective damage to the liver, the skin, and the gastrointestinal tract. Following allogeneic hematopoietic stem cell transplantation, donor bone marrow (BM) cells repopulate the...
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Influence of the central benzodiazepinergic system on peripheral cardiovascular regulation

Koh JT, Ju JM, Shin DH, Cho HH, Choi BK, Kim JH

  • KMID: 1849836
  • Korean J Physiol Pharmacol.
  • 1998 Jun;2(3):287-295.
Diazepam is known to have cardiovascular depressive effects through a combined action on benzodiazepinergic receptor and the GABA receptor-chloride ion channel complex. Moreover, it is known that barbiturates also have some cardiovascular regulatory...
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Protective Action of Purinergic and Cholinergic Agonists on the Ischemic Myocardium in the Rat

Kim JH, Park SD, Ju JM, Kook H, Cho JG, Park OK

BACKGROUND: Purinergic and cholinergic agonists elicit negative-inotropic and chronotropic effects, anticip-ating their protective action from the damage of overloaded myocardium. However, the actions of the agents during the ischemic insults...
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Effects of Oxygen Free Radicals on KATP Channel Activity in Mouse Cardiac Myocytes

Park HW, Ju JM, Park OY, Park WS, Kim JH, Kim W, Ahn YK, Jeong MH, Park JC, Kim JH, Kang JC, Cho JG

BACKGROUND AND OBJECTIVE: Oxygen-derived free radicals (OFRs), produced as myocardium is reperfused after ischemic injury, contribute to reversible and irreversible cellular injury. KATP channels, activated by ischemia, have been reported...
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Effects of Endothelium-derived Relaxing Factors on the Regulation of ATP-sensitive Potassium Channel Activity in Cardiac Myocytes

Ju JM, Shin DH, Jeong HS, Park HW, Cho JG, Kim JH

BACKGROUND AND OBJECTIVES: Effects of the three major endothelium-derived relaxing factors (EDRFs), namely nitric oxide (NO), prostacyclin (PGI2), and 11, 12-epoxyeicosatrienoic acid (EET) on the ATP-sensitive potassium channel (K ATP...
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Influences of Free Fatty Acids on Transmembrane Action Potential and ATP-sensitive Potassium Channel Activity in Rat Myocardium

Kim JH, Ju JM, Park J, Baik YH, Kook H, Jeong HS, Jeong MH, Cho JG, Park JC, Kang JC

BACKGROUND: To evaluate the role of free fatty acids on the ischemic myocardium, influences of various free fatty acids upon transmembrane action potential and ATP-sensitive K+(KATP) channel activity were examined...
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Influence of Vasoactive Substances on the Regulation of Cardiac ATP-Sensitive Potassium Channel Activity

Kim JH, Ju JM, Piao LH, Kim YY, Jeong HS, Park HW, Jeong DH, Lee SR, Yoon NS, Kim KH, Hong YJ, Kim JH, Kim W, Ahn YK, Jeong MH, Cho JG, Park JC, Kang JC

BACKGROUND AND OBJECTIVES: It has been known that various vasoactive agents are involved in the regulation of cardiac function through the modification of the K+ channel activities, including the ATP-sensitive...
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Skewed Dendritic Cell Differentiation of MyD88-Deficient Donor Bone Marrow Cells, Instead of Massive Expansion as Myeloid-Derived Suppressor Cells, Aggravates GVHD

Lee YK, Ju JM, Shon WJ, Oh S, Min CK, Kang MS, Shin DM, Choi EY

Graft-versus-host disease (GVHD), a life-threatening complication after bone marrow transplantation (BMT), is induced by activation of alloreactive donor T cells. Our previous study demonstrated that transplantation of myeloid differentiation factor...
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Effects of Oxygen Free Radical on Action Potential in Mouse Atrial Myocardium

Park HW, Jeong DH, Yoon NS, Koh JS, Lim SY, Lee SR, Hong SN, Kim KH, Sohn IS, Hong YJ, Kim JH, Kim W, Park RH, Ju JM, Ahn YK, Jeong MH, Cho JG, Kim JH, Park JC, Kang JC

BACKGROUND AND OBJECTIVES: Reactive oxygen species are known to be produced when atrial fibrillation develops. This study was performed to investigate the effects of hydrogen peroxide (H2O2) on the action...
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Changes in Preventable Death Rates and Traumatic Care Systems in Korea

Kim H, Jung KY, Kim SP, Kim SH, Noh H, Jang HY, Yoon HD, Heo YJ, Ryu HH, Jeong TO, Hwang Y, Ju JM, Joo MD, Han SK, Cho KW, Choi KH, Park JM, Jung HM, Lee SB, Kyong YY, Ryu JY, Jeon WC, Ahn JY, Lee JY, Ji HJ, Lee TH, Kim OH, Cha YS, Cha KC, Lee KH, Hwang SO

  • KMID: 2333101
  • J Korean Soc Emerg Med.
  • 2012 Apr;23(2):189-197.
PURPOSE: This study was performed in order to determine the changes over time in preventable and potentially preventable traumatic death rates, and to assess the factors that affected the deaths...
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