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Molecular Characterization of the L Segment of Hantann Virus, Strain Howang

Chu YK, Song DY, Koo HM, Lee HW

  • KMID: 1544247
  • J Korean Soc Virol.
  • 1999 Sep;29(3):155-163.
Hantaan virus (HTNV), the etiologic agent of hemorrhagic fever with renal syndrome (HFRS), belongs to the genus Hantavirus, and has three single negative straded RNA genome segments. HTNV strain Howang...
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Expression and Characterization of the Human Immunodeficiency Virus Type 1 Mutant Envelope Glycoproteins in Mammalian Cells

Ryu JY, Park JS

  • KMID: 1544250
  • J Korean Soc Virol.
  • 1999 Sep;29(3):183-193.
Human immunodeficiency virus type 1(HIV-1) envelope glycoprotein is synthesized as a 160KDa precursor, gp160, that is cleaved by a cellular protease to form the gp120 and gp41 subunits. Mammalian expression...
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Construction of a Novel Recombinant Baculovirus Producing Polyhedra with Bacillus thuringiensis Cry1Ac Crystal Protein

Je YH, Jin BR, Roh JY, Chan JH, Kang SK

  • KMID: 1544246
  • J Korean Soc Virol.
  • 1999 Sep;29(3):145-153.
We have now construted a novel recombinant baculovirus Autographa californica nuclear polyhedrosis virus (AcNPV) producing polyhedra with Bacillus thuringiensis (Bt) Cry1Ac crystal protein. The recombinant polyhedra produced by the recombinant...
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Expression and Purification of Herpes Simplex Virus Type 1 Protease

Bae PK, Paeng JW, Kim JH, Kim HS, Paik SG, Chung IK

  • KMID: 1544249
  • J Korean Soc Virol.
  • 1999 Sep;29(3):175-182.
An attractive target for anti-herpes chemotherapy is the herpes simplex virus 1 (HSV-1) protease encoded by the UL26 gene. HSV-1 protease is essential for DNA packaging and virus maturation. To...
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Efficacy of Acyclovir on Replication in Infected Tissues and Virus Reactivation from Explanted Tissues in Mouse Encephalitis Model of Herpes Simplex Virus Type 1

Lee CK, Kim JH, Bae PK, Pi MK, Kim HS

  • KMID: 1544248
  • J Korean Soc Virol.
  • 1999 Sep;29(3):165-174.
To investigate viral pathogenesis and in vivo efficacy of acyclovir (ACV) in mouse HSV-1 encephalitis models, female BALB/c mice aged 5 weeks were inoculated with strain F either intranasally (IN)...
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