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A Case of Hepatocellular Carcinoma in Non-alcoholic Fatty Liver Disease

Seok J, Suk KT, Kim DJ

Non-alcoholic fatty liver disease (NAFLD) has been one of the causes of cryptogenic hepatocellular carcinoma (HCC). NAFLD-associated HCC (NAFLD-HCC) have clinical features such as high body mass index, deranged lipid...
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Systemic Therapy for Advanced Hepatocellular Carcinoma: Targeted Therapy and Immunotherapy

Kim BH, Park JW

Systemic therapy for hepatocellular carcinoma (HCC) has markedly changed since 2007, with the approval of sorafenib. Sorafenib improved the overall survival of patients with advanced HCC; however, the modest efficacy...
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Translational Application of Single-cell Transcriptomic Analysis in Hepatocellular Carcinoma

Yoon SK

The emergence of single-cell technology in recent years has made remarkable progress for understanding of biological process in various diseases including cancers. In particular of cancer, single-cell transcriptome analysis provides...
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Needle-tract Seeding of Hepatocellular Carcinoma at Chest Wall: A Report of Two Cases

Kim DJ, Kim G

We report two cases of needle-tract seeding after cryoablation and radiofrequency ablation for hepatocellular carcinomas. The seeding nodule appeared 6 and 12 months on the follow-up computed tomographic scan, respectively....
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A Case of Hepatocellular Carcinoma Treated by Proton Beam Therapy as 1st Choice

Oh J, Sinn DH, Seong G, Chung HG, Heo C, Yu J, Park HC

Although first-line treatment option for single, small sized hepatocellular carcinoma in patients with preserved liver function and good performance status is resection or ablation, sometimes these modalities cannot be applied...
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Noninvasive Diagnostic Criteria of the Revised 2014 the Korean Liver Cancer Study Group and the National Cancer Center Guideline for Subcentimetersized Hepatocellular Carcinoma: Is It Too Strict?

Kim NJ, Sinn DH, Kang W, Paik YH, Choi MS, Lee JH, Koh KC, Paik SW, Gwak GY

BACKGROUND/AIMS: Noninvasive diagnostic criteria for hepatocellular carcinoma (HCC) differ between guidelines, especially for subcentimeter-sized nodules. This study aimed to analyze clinical and radiological characteristics of subcentimeter-sized HCC, and assess the...
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Tumor Response Evaluation after Treatment and Post-treatment Surveillance of Hepatocellular Carcinoma

Yoon JS, Park SY

Hepatocellular carcinoma is one of the most prevalent malignancies and frequent causes of death worldwide. Treatment options of hepatocellular carcinoma consist of locoregional therapy, surgical resection, liver transplantation, and systemic...
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A Case of Management for Advanced Hepatocellular Carcinoma with Extrahepatic Metastasis by Autologous Natural Killer Cells Combined with Immune Checkpoint Inhibitor

Woo A, Kim EJ, Shin SY, Jeon HJ, Park H, Chon YE, Lee YB, Hwang SG, Rim KS, Lee JH

Hepatocellular carcinoma (HCC) has extremely poor prognosis. Immunotherapy has emerged as a new treatment for a number of cancers. Adoptive immunotherapy is one of the important cancer immunotherapy, which relies...
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A Case of Complete Response with Biliary Stenosis after Hepatic Arterial Injection and Stereotactic Body Radiotherapy to Hepatoecllular Carcinoma with Portal Vein Thrombosis

Rim CH, Im HJ, Jung YG, Chung HH, Seo SJ, Yoon WS

Curative treatment of hepatocellular carcinoma (HCC) with portal vein invasion is difficult to achieve, and the prognosis is dismal. Combining external beam radiotherapy (EBRT) with hepatic arterial infusion chemotherapy (HAIC)...
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The Feasibility Study of Contrast-enhanced Ultrasound Using a 3 Dimension Transducer for Tumor Volume Measurement in Rabbit Hepatic VX2 Carcinoma Comparison with 2 Dimension Ultrasound and 3 Dimension Ultrasound without Contrast: Preliminary Results

Kim J, Kim JH, Choi SY, Han JK

BACKGROUND/AIMS: To investigate the feasibility of tumor volume measurement using contrastenhanced ultrasound (US) with 3 dimension transducer (3D CEUS) in rabbit hepatic VX2 carcinoma. METHODS: Three different tumor volume measurements, including...
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Spontaneous Regression of Massive Infiltrative Hepatocellular Carcinoma with Change in Hepatic Contour: A Case Report with Literature Review

Lee EH, Oh MJ

Spontaneous regression of hepatocellular carcinoma (HCC) is associated with alcohol abstinence, herbal medication, radiation, ischemia and immune reaction against systemic or local infections. Herein, we report a case of 67-year-old...
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Methionine Adenosyltransferase 1: A Proteomic Surrogate Marker of Early Hepatocellular Carcinoma in Cirrhotic Patients

Lee JH, Jun MJ, Shim JH, Song GW, Tak E, Oh B, Yu E, Choi SW, An J, Lee D, Kim KM, Lim YS, Lee HC, Chung YH, Lee YS

BACKGROUND/AIMS: Because there is a lack of effective biomarkers, we aimed to discover proteomic candidate markers for hepatocellular carcinoma (HCC) in cirrhotic patients at the highest-risk of HCC, and to...
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