- Gynecologic oncology in 2024: breakthrough trials and evolving treatment strategies for cervical, uterine corpus, and ovarian cancers
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Lee SJ, Yoo JG, Kim JH, Park JY, Lee JY, Lee YY, Suh DH
- KMID: 2565505
- J Gynecol Oncol.
- 2025 Jan;36(1):e72.
- doi: 10.3802/jgo.2025.36.e72
This review summarized the results of clinical trials in 2024 that were believed to have a significant impact on clinical practice in the field of gynecologic oncology. The SHAPE trial,... -
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- Clinical practice guidelines for ovarian cancer: an update to the Korean Society of Gynecologic Oncology guidelines
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Lee B, Chang SJ, Kwon BS, Son JH, Lim MC, Kim YH, Lee SW, Choi CH, Eoh KJ, Lee JY, Lee YY, Suh DH, Kim YB
- KMID: 2565450
- J Gynecol Oncol.
- 2025 Jan;36(1):e69.
- doi: 10.3802/jgo.2025.36.e69
We updated the Korean Society of Gynecologic Oncology (KSGO) practice guideline for the management of ovarian cancer as version 5.1. The ovarian cancer guideline team of the KSGO published announced... -
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- Clinical practice guidelines for cervical cancer: an update of the Korean Society of Gynecologic Oncology Guidelines
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Yoo JG, Lee SJ, Nam EJ, No JH, Park JY, Song JY, Shin SJ, Yun BS, Park ST, Lee SH, Suh DH, Kim YB, Lee KH
- KMID: 2565503
- J Gynecol Oncol.
- 2025 Jan;36(1):e70.
- doi: 10.3802/jgo.2025.36.e70
We describe the updated Korean Society of Gynecologic Oncology (KSGO) practice guideline for the management of cervical cancer, version 5.1. The KSGO announced the fifth version of its clinical practice... -
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- Clinical practice guidelines for uterine corpus cancer: an update to the Korean Society of Gynecologic Oncology guidelines
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Hwang WY, Kim JH, Noh JJ, Baek MH, Choi MC, Lee YJ, Lee M, Suh DH, Kim YB, Kim DY
- KMID: 2565504
- J Gynecol Oncol.
- 2025 Jan;36(1):e71.
- doi: 10.3802/jgo.2025.36.e71
The Korean Society of Gynecologic Oncology has updated its clinical practice guidelines for endometrial cancer to incorporate advancements in recent high-quality randomized controlled trials. These guidelines address evolving treatment paradigms,... -
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- Prognostic impact of the number of resected pelvic nodes in endometrial cancer: Japanese Gynecologic Oncology Group Study JGOG2043 post hoc analysis
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Konno Y, Mayama M, Takehara K, Yokoyama Y, Suzuki J, Susumu N, Harano K, Nakagawa S, Nakanishi T, Yamagami W, Yoshihara K, Nomura H, Okamoto A, Aoki D, Watari H
- KMID: 2565445
- J Gynecol Oncol.
- 2025 Jan;36(1):e3.
- doi: 10.3802/jgo.2025.36.e3
Objective: This study aimed to determine whether the number of resected pelvic lymph nodes (PLNs) affects the prognosis of endometrial cancer (EC) patients at post-operative risk of recurrence. Methods: JGOG2043 was... -
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- HER2-negative or low expression as an unfavorable prognostic factor in patients with stage I/II uterine carcinosarcoma
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Mizoguchi C, Nishikawa T, Yoshida H, Yasuda M, Kato T, Hasegawa K, Yonemori K
- KMID: 2565442
- J Gynecol Oncol.
- 2025 Jan;36(1):e14.
- doi: 10.3802/jgo.2025.36.e14
Objective: Uterine carcinosarcoma (UCS) is uncommon high-grade endometrial cancer with limited treatment options. We evaluated the prognostic significance of human epidermal growth factor receptor 2 (HER2) expression and HER2 gene... -
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- CHIPOR, HORSE, and beyond: unraveling the role of hyperthermic intraperitoneal chemotherapy (HIPEC) in ovarian cancer
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Lim MC
- KMID: 2565506
- J Gynecol Oncol.
- 2025 Jan;36(1):e73.
- doi: 10.3802/jgo.2025.36.e73
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- PRIMA: captivated by the wizard of OS?
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Marmé F
- KMID: 2565448
- J Gynecol Oncol.
- 2025 Jan;36(1):e55.
- doi: 10.3802/jgo.2025.36.e55
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- Phase II randomized study of dostarlimab alone or with bevacizumab versus non-platinum chemotherapy in recurrent gynecological clear cell carcinoma (DOVE/APGOT-OV7/ENGOT-ov80)
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Lee JY, Tan D, Ray-Coquard I, Lee JB, Kim BG, Nieuwenhuysen EV, Huang RYJ, Tse KY, González-Martin A, Scott C, Hasegawa K, Wilkinson K, Yang EY, Lheureux S, Kristeleit R
- KMID: 2565447
- J Gynecol Oncol.
- 2025 Jan;36(1):e51.
- doi: 10.3802/jgo.2025.36.e51
Background: Recurrent gynecological clear cell carcinoma (rGCCC) has a low objective response rate (ORR) to chemotherapy. Previous preclinical and clinical data suggest a potential synergy between immune checkpoint inhibitors and... -
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- Para-aortic lymph node dissection with or without nerve-sparing in gynecological malignancies
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Wen Q, Zhu Y, Zhou H, Yang L, Shao F, Zhu T, Shao Z
- KMID: 2565509
- J Gynecol Oncol.
- 2025 Jan;36(1):e9.
- doi: 10.3802/jgo.2025.36.e9
Objective: Para-aortic lymph node dissection (PALND) is a widely used treatment that causes many complications. This study is to evaluate the efficacy and safety of nerve-sparing para-aortic lymph node dissection... -
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- ATF1 regulates MAL2 expression through inhibition of miR-630 to mediate the EMT process that promotes cervical cancer cell development and metastasis
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Cao Y, Peng Y, Tang Y
- KMID: 2565439
- J Gynecol Oncol.
- 2025 Jan;36(1):e11.
- doi: 10.3802/jgo.2025.36.e11
Objective: The existence of activating transcription factor 1 (ATF1) could be employed as a clinical marker in the context of cervical cancer development, although its specific mechanism has not been... -
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- Efficacy and safety of cisplatin combined with paclitaxel concurrent radiotherapy in patients with locally advanced cervical squamous cell carcinoma
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Feng T, Zhang Y, Zheng G, Lv X, Yan D, Feng Y, Lou H
- KMID: 2565438
- J Gynecol Oncol.
- 2025 Jan;36(1):e10.
- doi: 10.3802/jgo.2025.36.e10
Objective: This study aimed to compare outcomes and adverse events of patients with locally advanced cervical cancer (LACC) undergoing concurrent chemoradiotherapy (CCRT) with cisplatin single-agent chemotherapy vs. CCRT with cisplatin... -
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- Prophylactic salpingectomy as a preventative strategy for ovarian cancer in the general population: a systematic review and meta-analysis
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Tang Y, Sun H, Fu P, Zhou T, Liu R
- KMID: 2565508
- J Gynecol Oncol.
- 2025 Jan;36(1):e8.
- doi: 10.3802/jgo.2025.36.e8
Objective: The impact of prophylactic salpingectomy on the prevention of epithelial ovarian cancer (EOC) remains unclear, particularly in Asian populations where data is lacking. In this systematic review and meta-analysis... -
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- Prevalence of high-risk human papillomavirus genotypes among women in Uzbekistan, 2021–2023
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Sharipova IP, Musabaev EI, Sadirova SS, Suyarkulova DT, Tashev SE, Akhmedova SK, Turabova NR, Sharapov SM, Kasimova RI, Rakhimov RA, Yuldashova GT, Lee K, Chun G, Kim H
- KMID: 2565507
- J Gynecol Oncol.
- 2025 Jan;36(1):e7.
- doi: 10.3802/jgo.2025.36.e7
Objective: Cervical cancer remains a significant global health concern. Extensive research has established a critical link between human papillomavirus (HPV) infection and the development of cervical cancer. As a result,... -
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- Cancer-field surgery for endometrial cancer by robotic peritoneal mesometrial resection and targeted compartmental lymphadenectomy (PMMR+TCL)
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Buderath P, Dang TM, Kimmig R
- KMID: 2565441
- J Gynecol Oncol.
- 2025 Jan;36(1):e13.
- doi: 10.3802/jgo.2025.36.e13
Objective: Cancer-field surgery by peritoneal mesometrial resection and targeted compartmental lymphadenectomy (PMMR+TCL) for the treatment of endometrial cancer (EC) aims at optimal locoregional tumor control without the need for adjuvant... -
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- Selective utilization of circulating tumor DNA testing enables disease monitoring in endometrial and ovarian carcinomas
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Jamieson A, McConechy MK, Lum A, Senz J, Dowhy T, Huntsman DG, McAlpine JN
- KMID: 2565449
- J Gynecol Oncol.
- 2025 Jan;36(1):e5.
- doi: 10.3802/jgo.2025.36.e5
Objective: Biomarkers reflecting real-time response to therapy and recurrence are lacking. We assessed the clinical value of detecting cell-free circulating tumor DNA (ctDNA) mutations in endometrial cancer (EC) and ovarian cancer... -
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- Investigation of selective glucocorticoid receptor modulation in high-grade serous ovarian cancer PDX models
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Taya M, Hou X, Veneris JT, Kazi N, Larson MC, Maurer MJ, Heinzen EP, Chen H, Lastra R, Oberg AL, Weroha SJ, Fleming GF, Conzen SD
- KMID: 2565446
- J Gynecol Oncol.
- 2025 Jan;36(1):e4.
- doi: 10.3802/jgo.2025.36.e4
Objective: In ovarian cancer (OvCa), tumor cell high glucocorticoid receptor (GR) has been associated with poor patient prognosis. In vitro, GR activation inhibits chemotherapyinduced OvCa cell death in association with... -
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- Nomogram for predicting pathology upstaging in patients with EIN: is sentinel lymph node assessment useful in these patients?
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Liang F, Xin W, Yang S, Wang H
- KMID: 2565443
- J Gynecol Oncol.
- 2025 Jan;36(1):e1.
- doi: 10.3802/jgo.2025.36.e1
Objective: The objective of this study was to identify the risk factors for postoperative pathological escalation of endometrial cancer in patients with a pathologic diagnosis of endometrial intraepithelial neoplasia (EIN)... -
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- Airborne and surface contamination after rotational intraperitoneal pressurized aerosol chemotherapy using cisplatin
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Jung W, Park M, Park SJ, Lee EJ, Kim HS, Kim S, Yoon C
- KMID: 2565440
- J Gynecol Oncol.
- 2025 Jan;36(1):e12.
- doi: 10.3802/jgo.2025.36.e12
Objective: We evaluated the occupational exposure levels of healthcare workers while conducting rotational pressurized intraperitoneal aerosol chemotherapy (RIPAC) using cisplatin in a large animal model. Methods: We performed RIPAC using cisplatin... -
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- Comparison of postoperative adjuvant platinum-based chemotherapy and no further therapy after radical surgery in intermediate-risk early-stage cervical cancer
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Nishimura H, Amano T, Yoneoka Y, Tsuji S, Taga Y, Aki M, Uno M, Moritani S, Murakami R, Kato T, Murakami T
- KMID: 2565444
- J Gynecol Oncol.
- 2025 Jan;36(1):e2.
- doi: 10.3802/jgo.2025.36.e2
Objective: To identify a relatively high-risk population in postoperative intermediate-risk cervical cancer and evaluate the effect of platinum-based adjuvant chemotherapy (CT). Methods: We retrospectively reviewed the medical records of patients with... -
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