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Epidemiology of Oral Lichen Planus in a Cohort of South Indian Population: A Retrospective Study

Varghese S, George GB, Sarojini S, Vinod S, Mathew P, Mathew DG, Sebastian , George A

BACKGROUND: Oral lichen planus (OLP) is an immune-mediated potentially malignant disorder of the oral cavity. Dysplastic OLP has an altered cytogenic profile and can progress into oral squamous cell carcinoma....
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Downregulation of Reactive Oxygen Species in Apoptosis

Jeong CH, Joo SH

Generation of reactive oxygen species (ROS) by diverse anti-cancer drugs or phytochemicals has been closely related with the induction of apoptosis in cancers. Also, the downregulation of ROS by these...
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The Potential Role of Nitric Oxide in Halting Cancer Progression Through Chemoprevention

Vahora H, Khan MA, Alalami U, Hussain A

Nitric oxide (NO) in general plays a beneficial physiological role as a vasorelaxant and the role of NO is decided by its concentration present in physiological environments. NO either facilitates...
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Implications of Graphic Cigarette Warning Labels on Smoking Behavior: An International Perspective

Jung M

Graphic warning labels (GWLs) have been developed as a representative non-price policy to block such marketing. This study investigated the current state and effect of the global introduction of GWLs...
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Dehydroglyasperin D Inhibits the Proliferation of HT-29 Human Colorectal Cancer Cells Through Direct Interaction With Phosphatidylinositol 3-kinase

Jung SK, Jeong CH

BACKGROUND: Despite recent advances in therapy, colorectal cancer still has a grim prognosis. Although licorice has been used in East Asian traditional medicine, the molecular properties of its constituents including...
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Comparison of Gastric Microbiota Between Gastric Juice and Mucosa by Next Generation Sequencing Method

Sung J, Kim N, Kim J, Jo HJ, Park JH, Nam RH, Seok YJ, Kim YR, Lee DH, Jung HC

BACKGROUND: Not much is known about the role of gastric microbiota except for Helicobacter pylori in human health and disease. In this study, we aimed to detect human gastric microbiota...
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Malvidin Protects WI-38 Human Fibroblast Cells Against Stress-induced Premature Senescence

Seo HR, Choi MJ, Choi JM, Ko JC, Ko JY, Cho EJ

BACKGROUND: Malvidin is one of the most abundant components in red wines and black rice. The effects of malvidin on aging and lifespan under oxidative stress have not been fully...
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Anti-inflammatory and Anti-tumorigenic Effects of Açai Berry in Helicobacter felis-infected mice

Lee JY, Kim N, Choi YJ, Nam RH, Lee S, Ham MH, Suh JH, Choi YJ, Lee HS, Lee DH

BACKGROUND: The aim of this study was to evaluate the anti-inflammatory and anti-tumorigenic effect of açai berry after chronic Helicobacter felis colonization in the stomachs of C57BL/6 mice. METHODS: A total...
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Ethanol Extract of Cirsium japonicum var. ussuriense Kitamura Exhibits the Activation of Nuclear Factor Erythroid 2-Related Factor 2-dependent Antioxidant Response Element and Protects Human Keratinocyte HaCaT Cells Against Oxidative DNA Damage

Yoo OK, Choi BY, Park JO, Lee JW, Park BK, Joo CG, Heo HJ, Keum YS

Keratinocytes are constantly exposed to extracellular insults, such as ultraviolet B, toxic chemicals and mechanical stress, all of which can facilitate the aging of keratinocytes via the generation of intracellular...
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Hyperoside Induces Endogenous Antioxidant System to Alleviate Oxidative Stress

Park JY, Han X, Piao MJ, Oh MC, Fernando P, Kang KA, Ryu YS, Jung U, Kim IG, Hyun JW

BACKGROUND: Hyperoside, a flavonoid which is mainly found in Hypericum perforatum L., has many biological effects. One of the most important effects is to prevent the oxidative stress induced by...
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