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Obstructive Sleep Apnea Screening Using a Piezo-Electric Sensor

Erdenebayar U, Park JU, Jeong P, Lee KJ

In this study, we propose a novel method for obstructive sleep apnea (OSA) detection using a piezo-electric sensor. OSA is a relatively common sleep disorder. However, more than 80% of...
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Generation of Whole-Genome Sequencing Data for Comparing Primary and Castration-Resistant Prostate Cancer

Park JL, Kim SK, Kim JH, Yun SJ, Kim WJ, Kim WT, Jeong P, Kang HW, Kim SY

Because castration-resistant prostate cancer (CRPC) does not respond to androgen deprivation therapy and has a very poor prognosis, it is critical to identify a prognostic indicator for predicting high-risk patients...
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Stress-Activated Protein Kinase/c-Jun NH2 Terminal Kinase (SAPK/JNK) Expression in Transitional Cell Carcinoma of the Urinary Bladder

Park H, Kim EJ, Jeong P, Kim CS, Ahn H, Kim WJ

  • KMID: 2292390
  • Korean J Urol.
  • 2002 Feb;43(2):117-124.
PURPOSE: The SAPK/JNK group of MAP (mitogen-activated protein) kinases is known to regulate cellular proliferation, apoptosis and tissue morphogenesis. This study was performed to assess the clinical usefulness of the...
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Effects of Genotype of Tumor Necrosis Factor Alpha Promoter on Bladder Tumor Grade

Jeong P, Kim WJ, Kim EJ, Kim JS, Eum MS, Lee SC

  • KMID: 2060982
  • Korean J Urol.
  • 2002 Mar;43(3):224-230.
Purpose: Several polymorphic sites have been reported in the tumor necrosis factor alpha (TNF-alpha) promoter. Comparative studies on TNF-alpha production with promoter genotype have reported variable results, particularly in the...
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Polymorphisms of Human 8-Oxoguanine Glycosylase1 (hOGG1) in Bladder Tumor

Kim EJ, Jeong P, Jung CG, Kim WJ

  • KMID: 2060980
  • Korean J Urol.
  • 2002 Mar;43(3):213-218.
Purpose: Repairing damaged DNA has been shown to be involved in an increased susceptibility to cancer development and prevention. Therefore, the genetic polymorphisms of the hOGG1 gene associated with the...
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Expression and Correlation of Cyclooxygenase-2, Angiogenin and Vascular Endothelial Growth Factor in Human Transitional Cell Carcinoma

Jang H, Lee YS, Jo S, Jeong P, Lee SC, Kim WJ, Lee HL

  • KMID: 2293984
  • Korean J Urol.
  • 2005 Jul;46(7):683-689.
PURPOSE: The role of cyclooxygenase (COX)-2 on the tumorigenesis and progression of human solid organ tumor is unknown, but recent studies have supported an important role for COX-2 in various...
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Clinical Significance of the Expression of Gli2 and Gli3 in Bladder Cancer

Han KH, Chae Y, Jeong P, Kim YJ, Yun SJ, Lee SC, Kim WJ

  • KMID: 2311946
  • Korean J Urol.
  • 2008 Aug;49(8):696-702.
PURPOSE: The HedgehogGli(HHGli) signaling pathway controls many aspects of tissue patterning, cell proliferation, differentiation and regeneration, and regulates the number of cells in various organs. Inappropriate and uncontrolled activation of...
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A novel urinary mRNA signature using the droplet digital polymerase chain reaction platform improves discrimination between prostate cancer and benign prostatic hyperplasia within the prostate-specific antigen gray zone

Kang HW, Lee HY, Byun YJ, Jeong P, Yoon JS, Kim DH, Kim WT, Kim YJ, Lee SC, Yun SJ, Kim WJ

Purpose: The aim of this study was to identify a noninvasive urinary marker for prostate cancer (PCa) diagnosis and to validate the clinical performance of this novel urinary mRNA signature...
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GSTM1 Tissue Genotype as a Recurrence Predictor in Non-muscle Invasive Bladder Cancer

Ha YS, Yan C, Jeong P, Kim WT, Yun SJ, Yi Kim I, Moon SK, Kim WJ

Tissue genotyping is more useful approach than using blood genomic DNA, which can reflect the effects of the somatic mutations in cancer. Although polymorphisms in glutathione S-transferase (GST) have been...
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Urinary microRNA-1913 to microRNA-3659 expression ratio as a non-invasive diagnostic biomarker for prostate cancer

Byun YJ, Piao XM, Jeong P, Kang HW, Seo SP, Moon SK, Lee JY, Choi YH, Lee HY, Kim WT, Lee SC, Cha EJ, Yun SJ, Kim WJ

Purpose: MicroRNAs (miRNAs) are small non-coding RNAs and are involved in the development, proliferation, and pathogenesis of prostate cancer (PCa). Urinary miRNAs are promising non-invasive biomarkers for PCa diagnosis because...
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Urinary Nucleic Acid TSPAN13-to-S100A9 Ratio as a Diagnostic Marker in Prostate Cancer

Yan C, Kim YH, Kang HW, Seo SP, Jeong P, Lee IS, Kim D, Kim JM, Choi YH, Moon SK, Yun SJ, Kim WJ

The potential use of urinary nucleic acids as diagnostic markers in prostate cancer (PCa) was evaluated. Ninety-five urine samples and 234 prostate tissue samples from patients with PCa and benign...
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Novel Combination Markers for Predicting Survival in Patients with Muscle Invasive Bladder Cancer: USP18 and DGCR2

Kim YH, Kim WT, Jeong P, Ha YS, Kang HW, Yun SJ, Moon SK, Choi YH, Kim IY, Kim WJ

We performed gene expression profiling in bladder cancer patients to identify cancer-specific survival-related genes in muscle invasive bladder cancer (MIBC) patients. Sixty-two patients with MIBC were selected as the original...
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Value of urinary topoisomerase-IIA cell-free DNA for diagnosis of bladder cancer

Kim YH, Yan C, Lee IS, Piao XM, Byun YJ, Jeong P, Kim WT, Yun SJ, Kim WJ

PURPOSE: Topoisomerase-II alpha (TopoIIA ), a DNA gyrase isoform that plays an important role in the cell cycle, is present in normal tissues and various human cancers, and can show...
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CDC6 mRNA Expression Is Associated with the Aggressiveness of Prostate Cancer

Kim YH, Byun YJ, Kim WT, Jeong P, Yan C, Kang HW, Kim YJ, Lee SC, Moon SK, Choi YH, Yun SJ, Kim WJ

BACKGROUND: Cell division cycle 6 (CDC6) is an essential regulator of DNA replication and plays important roles in the activation and maintenance of the checkpoint mechanisms in the cell cycle....
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Erratum: Increased Expression of Herpes Virus-Encoded hsv1-miR-H18 and hsv2-miR-H9-5p in Cancer-Containing Prostate Tissue Compared to That in Benign Prostate Hyperplasia Tissue

Yun SJ, Jeong P, Kang HW, Shinn HK, Kim YH, Yan C, Choi YK, Kim D, Ryu DH, Ha YS, Kim TH, Kwon TG, Kim JM, Suh SH, Kim SK, Kim SY, Kim ST, Kim WT, Lee OJ, Moon SK, Kim NH, Kim IY, Kim J, Cha HJ, Choi YH, Cha EJ, Kim WJ

In this article, a part of fund and grant supports was omitted unintentionally.
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Metabolic Pathway Signatures Associated with Urinary Metabolite Biomarkers Differentiate Bladder Cancer Patients from Healthy Controls

Kim WT, Yun SJ, Yan C, Jeong P, Kim YH, Lee IS, Kang HW, Park S, Moon SK, Choi YH, Choi YD, Kim IY, Kim J, Kim WJ

PURPOSE: Our previous high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry study identified bladder cancer (BCA)-specific urine metabolites, including carnitine, acylcarnitines, and melatonin. The objective of the current study was to determine...
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Urinary MicroRNAs of Prostate Cancer: Virus-Encoded hsv1-miRH18 and hsv2-miR-H9-5p Could Be Valuable Diagnostic Markers

Yun SJ, Jeong P, Kang HW, Kim YH, Kim EA, Yan C, Choi YK, Kim D, Kim JM, Kim SK, Kim SY, Kim ST, Kim WT, Lee OJ, Koh GY, Moon SK, Kim IY, Kim J, Choi YH, Kim WJ

PURPOSE: MicroRNAs (miRNAs) in biological fluids are potential biomarkers for the diagnosis and assessment of urological diseases such as benign prostatic hyperplasia (BPH) and prostate cancer (PCa). The aim of...
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Increased Expression of Herpes Virus-Encoded hsv1-miR-H18 and hsv2-miR-H9-5p in Cancer-Containing Prostate Tissue Compared to That in Benign Prostate Hyperplasia Tissue

Yun SJ, Jeong P, Kang HW, Shinn HK, Kim YH, Yan C, Choi YK, Kim D, Ryu DH, Ha YS, Kim TH, Kwon TG, Kim JM, Suh SH, Kim SK, Kim SY, Kim ST, Kim WT, Lee OJ, Moon SK, Kim NH, Kim IY, Kim J, Cha HJ, Choi YH, Cha EJ, Kim WJ

PURPOSE: Previously, we reported the presence of virus-encoded microRNAs (miRNAs) in the urine of prostate cancer (CaP) patients. In this study, we investigated the expression of two herpes virus-encoded miRNAs...
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