- The Impact of Autophagy on the Cigarette Smoke Extract-Induced Apoptosis of Bronchial Epithelial Cells
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Lee CH, Lee KH, Jang AH, Yoo CG
- KMID: 2396345
- Tuberc Respir Dis.
- 2017 Jan;80(1):83-89.
- doi: 10.4046/trd.2017.80.1.83
BACKGROUND: Previous studies report that apoptosis and autophagy are involved in the pathogenesis of emphysema, and macroautophagy is one of the processes regulating the apoptosis pathway. However, few studies have... -
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- Metformin Reduces Bleomycin-induced Pulmonary Fibrosis in Mice
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Choi SM, Jang AH, Kim H, Lee KH, Kim YW
- KMID: 2468274
- J Korean Med Sci.
- 2016 Sep;31(9):1419-1425.
- doi: 10.3346/jkms.2016.31.9.1419
Metformin has anti-inflammatory and anti-fibrotic effects. We investigated whether metformin has an inhibitory effect on bleomycin (BLM)-induced pulmonary fibrosis in a murine model. A total of 62 mice were divided... -
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