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Using Periostin as a Biomarker in the Treatment of Asthma

Izuhara K, Ohta S, Ono J

Periostin acts both as an extracellular matrix protein belonging to the fasciclin family and as a matricellular protein functioning in cell activation by binding to its receptors on the cell...
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Serum Periostin Is Negatively Correlated With Exposure to Formaldehyde and Volatile Organic Compounds in Children

Yon DK, An J, Ha EK, Jee HM, Izuhara K, Ono J, Jung YH, Lee KS, Sheen YH, Baek H, Han MY

Epidemiological studies have shown that exposure to tobacco smoke causing irritation and inflammation in the airways tends to reduce serum periostin concentrations in adults. We now investigate prospective cross-sectional study...
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Periostin and Interleukin-13 Are Independently Related to Chronic Spontaneous Urticaria

Bae Y, Izuhara K, Ohta S, Ono J, Hong GU, Ro JY, Park GH, Choi JH

Chronic spontaneous urticaria (CSU) is a complex idiopathic disease of the skin with various cellular infiltrations. Although mast cells are key effector cells in the pathogenesis of CSU, CD4+ T...
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Serum Periostin Levels: A Potential Serologic Marker for Toluene Diisocyanate-Induced Occupational Asthma

Lee JH, Kim SH, Choi Y, Trinh HK, Yang EM, Ban GY, Shin YS, Ye YM, Izuhara K, Park HS

PURPOSE: Toluene diisocyanate (TDI) is a leading cause of occupational asthma (OA). Periostin is a matricellular protein implicated in type 2 immunity-driven asthma. Its pathogenic role in TDI-OA has not...
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