- Small Intestinal Bacterial Overgrowth in Patients with Refractory Functional Gastrointestinal Disorders
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Shimura S, Ishimura N, Mikami H, Okimoto E, Uno G, Tamagawa Y, Aimi M, Oshima N, Sato S, Ishihara S, Kinoshita
- KMID: 2379704
- J Neurogastroenterol Motil.
- 2016 Jan;22(1):60-68.
- doi: 10.5056/jnm15116
BACKGROUND/AIMS: Small intestinal bacterial overgrowth (SIBO) is considered to be involved in the pathogenesis of functional gastrointestinal disorders (FGID). However, the prevalence and clinical conditions of SIBO in patients with... -
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- Advantages and Disadvantages of Long-term Proton Pump Inhibitor Use
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Kinoshita , Ishimura N, Ishihara S
- KMID: 2413095
- J Neurogastroenterol Motil.
- 2018 Apr;24(2):182-196.
- doi: 10.5056/jnm18001
Proton pump inhibitors (PPIs) potently inhibit gastric acid secretion and are widely used for treatment of acid-related diseases including gastroesophageal reflux disease and secondary prevention of aspirin/NSAID-induced ulcers. Although clinically... -
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- Evaluations of Gastric Acid Pocket Using Novel Vertical 8-Channel pH Monitoring System and Effects of Acid Secretion Inhibitors
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Sumi S, Ishimura N, Mikami H, Okimoto E, Tamagawa Y, Mishiro T, Kinoshita Y, Ishihara S
- KMID: 2517531
- J Neurogastroenterol Motil.
- 2021 Jul;27(3):370-376.
- doi: 10.5056/jnm20115
Background/Aims The gastric acid pocket has an important role in gastroesophageal reflux disease development. In this study, we utilized a novel 8-channel pH monitoring system with sensor intervals of 1 cm... -
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- Acotiamide Has No Effects on Esophageal Motor Activity or Esophagogastric Junction Compliance
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Mikami H, Ishimura N, Okada M, Izumi D, Okimoto E, Ishihara S, Kinoshita
- KMID: 2413100
- J Neurogastroenterol Motil.
- 2018 Apr;24(2):241-247.
- doi: 10.5056/jnm16111
BACKGROUND/AIMS: The novel prokinetic drug acotiamide is used for treatment of functional dyspepsia. It is still unclear how acotiamide has effects on esophageal motor function. Esophageal peristalsis and esophagogastric junction... -
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- Effects of Metoclopramide on Esophageal Motor Activity and Esophagogastric Junction Compliance in Healthy Volunteers
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Mikami H, Ishimura N, Fukazawa K, Okada M, Izumi D, Shimura S, Okimoto E, Aimi M, Ishihara S, Kinoshita
- KMID: 2379710
- J Neurogastroenterol Motil.
- 2016 Jan;22(1):112-117.
- doi: 10.5056/jnm15130
BACKGROUND/AIMS: Prokinetic drugs such as metoclopramide are frequently used as second-line therapy for patients with gastroesophageal reflux disease. However, their beneficial effects remain unclear. Esophageal motor activities and compliance of... -
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