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Cardiovascular disease: extraintestinal manifestation of inflammatory bowel disease

Lakhanpal S, Aggarwal K, Kaur H, Kanwar K, Gupta V, Bhavsar J, Jain R

Inflammatory bowel disease (IBD) is a spectrum of diseases characterized by the interplay of the aberrant immune system, genetic factors, environmental factors, and intestinal microbiota, resulting in relapsing inflammation of...
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The impact of COVID-19 on clinical practices of colorectal cancer in South Korea

Kim KW, Kang HW

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Elucidating the association between nonalcoholic fatty liver disease and incidence of inflammatory bowel disease: a focus on systemic inflammation

Kim S, Im JP

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In which patients with ulcerative colitis would filgotinib be effective?

Park J

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The impact of the COVID-19 pandemic on clinical practices related to colorectal cancer and colonoscopy in South Korea: a nationwide population-based study

Yoon JY, Lee MH, Kwak MS, Cha JM

Background/Aims: Despite of the coronavirus disease 2019 (COVID-19) pandemic, there is little data regarding its impact on colorectal cancer (CRC)-related clinical practice. This study aimed to assess the changes in...
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Optimizing 5-aminosalicylate for moderate ulcerative colitis: expert recommendations from the Asia-Pacific, Middle East, and Africa Inflammatory Bowel Disease Coalition

Akyüz F, An YK, Begun J, Aniwan S, Bui HH, Chan W, Choi CH, Chopdat N, Connor SJ, Desai D, Flanagan E, Kobayashi T, Lai AYH, Leong RW, Leow AHR, Leung WK, Limsrivilai J, Muzellina VN, Peddi K, Ran Z, Wei SC, Sollano J, Teo MMH, Wu K, Ye BD, Ooi CJ

The lack of clear definition and classification for “moderate ulcerative colitis (UC)” creates ambiguity regarding the suitability of step-up versus top-down treatment approaches. In this paper, experts address crucial gaps...
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Combined eosinophilic gastroenteritis and ulcerative colitis successfully treated by vedolizumab: a case report

Takedomi H, Fukuda K, Inoue S, Tsuruoka N, Sakata Y, Aoki S, Esaki M

A 47-year-old man with over 10 years’ duration of ulcerative colitis treated by 5-aminosalicylic acid and intermittent topical steroids complained of acute epigastric pain. Esophagogastroduodenoscopy revealed diffuse mucosal edema with...
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Bowel movement alterations predict the severity of diverticular disease and the risk of acute diverticulitis: a prospective, international study

Tursi A, Piovani D, Brandimarte G, Di Mario F, Elisei W, Picchio M, Figlioli G, Bassotti G, Allegretta L, Annunziata ML, Bafutto M, Bianco MA, Colucci R, Conigliaro R, Dumitrascu DL, Escalante R, Ferrini L, Forti G, Franceschi M, Graziani MG, Lammert F, Latella G, Lisi D, Maconi G, Compare D, Nardone G, Camara de Castro Oliveira L, Enio CO, Papagrigoriadis S, Pietrzak A, Pontone S, Stundiene I, Poškus T, Pranzo G, Reichert MC, Rodino S, Regula J, Scaccianoce G, Scaldaferri F, Vassallo R, Zampaletta C, Zullo A, Spaziani E, Bonovas S, Papa A, Danese S, DICA International Group

Background/Aims: Patients with diverticular disease (DD) frequently have abnormal bowel movements. However, it is unknown whether the entity of these alterations is associated with the severity of DD. We aimed...
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The prevalence of pouch fistulas in ulcerative colitis following restorative proctocolectomy: a systematic review and meta-analysis

Lo SW, Dharia I, Sriranganathan D, Kayal M, Barnes EL, Segal JP

Background/Aims: One complication of restorative proctocolectomy with ileo-anal pouch anastomosis is fistula formation in the pouch. Fistulas can be associated with significant morbidity and pouch failure. We conducted a systematic...
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Filgotinib induction-study baseline characteristics of patients with ulcerative colitis who achieve sustained corticosteroid-free remission: post hoc analysis of the phase 2b/3 SELECTION study

Kobayashi T, Dignass A, Roblin X, Takatori Y, Kaise T, Oortwijn A, Jamoul C, Hibi T

Background/Aims: Obtaining and maintaining corticosteroid-free remission are important goals of treatment for ulcerative colitis (UC). Characteristics associated with achieving corticosteroid-free remission were assessed in filgotinib-treated patients in SELECTION, a 58-week,...
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Association between nonalcoholic fatty liver disease and incidence of inflammatory bowel disease: a nationwide population‑based cohort study

Wang YH, Chung CH, Huang TY, Chang CF, Yang CW, Chien WC, Cheng YC

Background/Aims: Nonalcoholic fatty liver disease (NAFLD) is a common disease with severe inflammatory processes associated with numerous gastrointestinal diseases, such as inflammatory bowel disease (IBD). Therefore, we investigated the relationship...
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Helminths in alternative therapeutics of inflammatory bowel disease

Pandey H, Tang DWT, Wong SH, Lal D

Inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, is a nonspecific chronic inflammation of the gastrointestinal tract. Despite recent advances in therapeutics and newer management strategies, IBD...
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