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A comparative study of the prevalence of Helicobacter pylori in the oral biofilms of a group of dental and nondental undergraduates from Sri Lanka

Mallikaarachchi M, Rajapakse S, Gunawardhana K, Jayatilake J

Dental health care workers (DHCW) are at a risk of occupational exposure to Helicobacter pylori from the aerosolized oral biofilms and saliva of patients. We designed this study to investigate...
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Expression of neurotransmitter receptors in oral keratinocytes and their response to agonists

Choi EJ, Chang SH, Choi SY, Choi Y

This study aimed to investigate whether neurotransmitter receptors in the nervous system were also expressed in oral keratinocytes. Expressions of various neurotransmitter receptor genes in immortalized mouse oral keratinocyte (IMOK)...
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The antibacterial effect of Endoseal TCS mixed with water-soluble mangostin derivatives of Garcinia mangostana L. ethanol extract against Enterococcus faecalis and Staphylococcus aureus

Park TY, Lim YK, Kim JH, Lee DS, Kook JK

This study evaluated the antimicrobial activity of Endoseal TCS, an mineral trioxide aggregate-based root canal sealer, mixed with water-soluble mangostin derivatives (WsMD) of Garcinia mangostana L. (mangosteen) ethanol extract against...
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Vinpocetine inhibits the proliferation and induces apoptosis in human colon cancer cells

Kim MK, Park HJ, Kim Y, Kim YI, Bae SK, Kim HJ, Bae MK

Vinpocetine induces anti-inflammatory effects in various inflammatory diseases via the inhibition of phosphodiesterase type-1-independent nuclear factor-κB signaling pathway and the release of inflammatory cytokines. In this study, we investigated the...
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Nucleic acid-based molecular diagnostic testing of SARS-CoV-2 using self-collected saliva specimens

Hwang EC, Kim JH

Since the outbreak of coronavirus disease 2019 (COVID-2019), the infection has spread worldwide due to the highly contagious nature of severe acute syndrome coronavirus (SARS-CoV-2). To manage SARS-CoV-2, the development...
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Autophagy inhibition by cudraxanthone D regulates epithelial–mesenchymal transition in SCC25 cells

Yu SB, Bang TH, Kang HM, Park BS, Kim IR

Cudraxanthone D (CD) is a natural xanthone compound derived from the root barks of Cudrania tricuspidata . However, the biological functions of CD in human metabolism have been rarely reported...
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Baicalin suppresses lipopolysaccharide-induced matrix metalloproteinase expression: action via the mitogenactivated protein kinase and nuclear factor κB-related protein signaling pathway

Ko SY

Periodontal disease is an inflammatory disease that affects the destruction of the bone supporting the tooth and connective tissues surrounding it. Periodontal ligament fibroblasts (PDLFs) induce overexpression of matrix metalloproteinase...
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Alpha-lipoic acid protects human dopaminergic neuronal cells against hydrogen peroxide-induced cell injury by inhibiting autophagy and apoptosis

Kang KR, Kim JS, Kim TH, Seo JY, Lim H, Park JH, Yang KY, Yu SK, Kim HJ, Kim CS, Chun HS, Lee DS, Park JC, Kim DK

Alpha-lipoic acid (ALA) is a naturally occurring antioxidant and has been previously used to treat diabetes and cardiovascular disease. However, the autophagy effects of ALA against oxidative stress-induced dopaminergic neuronal...
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Apoptotic activity of demethoxycurcumin in MG-63 human osteosarcoma cells

Kang KR, Kim JS, Kim TH, Seo JY, Park JH, Chun HS, Yu SK, Kim HJ, Kim CS, Kim DK

Demethoxycurcumin (DMC), which is a curcuminoid found in turmeric, has anti-proliferative effects on cancer cells. However, the effect of DMC on osteosarcoma has not been established. The aim of this...
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