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Effect of the Ethanol Extract of Propolis on Formation of Streptococcus mutans Biofilm

Park BI, Jung YW, Kim YH, Lee SM, Kwon LS, Kim KJ, An SY, Choi NY, You YO

Streptococcus mutans (S. mutans) is one of the most important bacteria in the formation of dental plaque and dental caries. S. mutans adheres to an acquired pellicle formed on the...
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An Evaluation of the Repetitive Tooth Bleaching with Nonthermal Atmospheric Pressure Plasma

Nam SH, Kim GC, Hong JW

This study was undertaken to achieve a high bleaching efficacy with plasma, through longer application and reparative bleaching processes, by different shade evaluation methods. Extracted human teeth were divided into...
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Expression of Inflammasome Complex Following Various Oral Bacterial Infection in THP-1 Cells

Na HS, Kim SM, Song YR, Kim S, Chung J

Interleukin-1b (IL-1β), a proinflammatory cytokine, regulates the innate immune responses against bacterial infection. Mature IL-1β is produced from pro-IL-1β by activated caspase-1, which in turn is activated by the inflammasome...
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Reactive Oxygen Species are Involved in Y-27632-induced Neurite Outgrowth in PC12 Cells

Park SY, Moon SA, An JM, Kim DS, Seo JT

Inhibition of Rho-associated coiled coil-containing kinase (ROCK) has been reported to promote differentiation of neuronal cells. Here, we examined the effect of Y-27632, a ROCK inhibitor, on the outgrowth of...
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Mongolian Gerbil as a Novel Animal Model for Ligature-induced Periodontitis

Jang S, Bak EJ

Inflammation from chronic and acute infections of distal organs and tissues such as periodontitis is a risk factor for atherosclerotic vascular processes. Recently, a new model of atherosclerosis with vascular...
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Porphyromonas gingivalis Lipopolysaccharide Regulates Migration of Vascular Smooth Muscle Cells

Kim Y, Kim SJ, Kim MK, Park HJ, Kim HJ, Bae SK, Bae MK

Porphyromonas gingivalis, a foremost periodontal pathogen, has been known to cause periodontal diseases. Epidemiologic evidences have indicated the involvement of P. gingivalis in the development of cardiovascular diseases. In this...
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Effect of Sub-minimal Inhibitory Concentration of Chlorhexidine on Biofilm Formation and Coaggregation of Early Colonizers, Streptococci and Actinomycetes

Lee SY, Lee SY

Chlorhexidine has long been used in mouth washes for the control of dental caries, gingivitis and dental plaque. Minimal inhibitory concentration (MIC) is the lowest concentration of an antimicrobial substance...
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Identification of Non-Aggregatibacter actinomycetemcomitans Bacteria Grown on the Tryptic soy-Serum-Bacitracin-Vancomycin Medium

Jo E, Park SN, Kook JK

The aim of this study was to identify the non-Aggregatibacter actinomycetemcomitans bacteria grown on the tryptic soy-serum-bacitracin-vancomycin (TSBV) medium, an A. actinomycetemcomitans selective medium. A total of 82 unidentified bacterial...
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Vitamin E Potentiates the Anti-nociceptive Effects by Intraperitoneal Administration of Lidocaine in Rats

Kim HJ, Yang HJ, Kim SH, Kim DA, Kim SJ, Park HN, Ju JS, Ahn DK

The present study was to evaluate effects of vitamin E on intravenous administration of lidocaine-induced antinociception. Experiments were carried out using male Sprague-Dawley rats. Orofacial formalin-induced nociceptive behavioral responses were...
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Anti-cancer Activity of Anthricin through Caspase-dependent Apoptosis in Human Hypopharyngeal Squamous Carcinoma Cell

Kim WG, Lee SA, Moon SM, Kim JS, Kim SG, Shin YK, Kim DK, Kim CS

Anthricin (Deoxypodophyllotoxin), a naturally occurring flavolignan, has well known anti-cancer properties in several cancer cells, such as prostate cancer, cervical carcinoma and pancreatic cancer. However, the effects of Anthricin are...
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Influence of Tyrosol on Cell Growth Inhibition of KB Human Oral Cancer Cells

Lee UK, Kim SG, Go DS, Yu SK, Kim CS, Kim J, Kim DK

Tyrosol, a phenylethanoid and a derivative of phenethyl alcohol, possesses various biological properties, such as anti-oxidative and cardioprotective activity. Olive oil is the principal source of tyrosol in the human...
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Inhibitory Effect of Myricetin on Matrix Metalloproteinase Expression and Activity in Periodontal Inflammation

Ko SY

Flavonoid myricetin, usually found in tea and medicinal plants, has antioxidant and anti-inflammatory effects. Our objectives in this study were to verify the effects of myricetin on periodontal ligament fibroblasts...
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