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Differential diagnosis of ovarian cancer and benign ovarian diseases using cytokine levels in the peritoneal fluids

Yang SM, Song KE, Suh JS, Cho YL

  • KMID: 2225973
  • Korean J Clin Pathol.
  • 2000 Dec;20(6):527-533.
BACKGROUND: Cytokines play a key role in the regulation of cells of the immune system and also have been implicated in the pathogenesis of malignant disease. Usually malignant cells secreted...
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Activity of Cytokines and Expression of CD62L in Patients with Bronchial Asthma

Song KS, Lee WY, Hong AR, Kim HS, Yong SJ, Shin KC

BACKGROUND: The CD4+ T-helper cells comprise functionally distinct subsets of Th1 and Th2 cells that are distinguished on the basis of differential cytokines production. Th1 cells secrete interferon-gamma, lymphotoxin, interleukin-2....
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Comparison of cytokine expression profiles in infants with a rhinovirus induced lower respiratory tract infection with or without wheezing: a comparison with respiratory syncytial virus

Roh DE, Park SH, Choi HJ, Kim YH

PURPOSE: The aim of this study was to evaluate whether infants with rhinovirus (RV) infection-induced wheezing and those with respiratory syncytial virus (RSV) infection-induced wheezing have different cytokine profiles in...
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The Effect of Bacterial Lipopolysaccharide on the Lymphokine Production of the T Lymphocytes

Moon HB, Yun KJ, Han WC, Lim CW, Kwon HN, Park YS

  • KMID: 1725230
  • Korean J Pathol.
  • 1997 Mar;31(3):244-251.
It is well known that the murine T helper cell clones are divided by their lymphokine secretory activities. One is the Th-1 cell, producing IL-2 and IFN after...
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Interleukin-10 is increased in successful drug desensitization regardless of the hypersensitivity reaction type

Gelincik A, Demir S, Şen F, Bozbey UH, Olgaç M, Ünal D, Çolakoğlu B, Aktaş EC, Deniz G, Büyüköztürk S

BACKGROUND: Little is known about the mechanism of desensitization in hypersensitivity drug reactions. OBJECTIVE: The aim of this study was to evaluate the effects of drug desensitization on some cytokine levels...
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Plasma Interferon(IFN)-gamma, Interleukin(IL)-4, IL-5 and IL-10 Concentrations in Atopic Dermatitis

Noh GW, Lee KY

  • KMID: 2139036
  • Pediatr Allergy Respir Dis.
  • 1998 Mar;8(1):72-78.
PURPOSE: There is reduced IFN-gamma production with increased IL-4 production in atopic dermatitis. IgE production is known to increase from an imbalance of IFN-gamma and IL-4 production. IgE overproduction...
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Tuberculin Skin Test and Change of Cytokines in Patients with Allergic Asthma

Yoon HK, Shin Y, Lee SH, Lee SY, Kim SC, Ahn JH, Kim KH, Moon HS, Park SH, Song JS

BACKGROUND: Bronchial asthma is characterized by chronic eosinophilic inflammatory airway disease associated with bronchial hyperresponsiveness and reversible airway obstruction. Bronchial inflammation in asthma may depend in part on the activation...
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Mycoplasma pneumoniae Infection Affects the Serum Levels of Vascular Endothelial Growth Factor and Interleukin-5 in Atopic Children

Jeong YC, Yeo MS, Kim JH, Lee HB, Oh JW

PURPOSE: Previous studies have outlined mechanisms by which Mycoplasma pneumonia (M. pneumonia) infection may promote allergic lung inflammation and airway remodeling, and increasing evidence from human studies suggests that atypical...
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Effective Microorgainsm (EM) Fermentation Extract Attenuates Airway Hyperreactivity and Lung Inflammation In A Mouse Model of Asthma

Do JS, Choi YH, Seo HJ, Ryoo JH, Nam SY

Effective microorganism (EM) fermentation extract has been widely used for agricultural and environmental application. It has been recently revealed that EM cocktail treatment may be effective for treatment of diseases...
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Higher Binding Affinity and In Vitro Potency of Reslizumab for Interleukin-5 Compared With Mepolizumab

Liddament , Husten J, Estephan T, Laine D, Mabon D, Pukac L, Lyons J, Clarke AW, Doyle A

Reslizumab and mepolizumab are recently approved monoclonal antibodies for the treatment of severe (uncontrolled) eosinophilic asthma. Both are effective in neutralizing the function of interleukin-5 (IL-5). This study is the...
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The Differentiation of HL-60 Cells Causes to Lose their Ability to Express TNF mRNA

Kim JH, Han SJ, Park CS, Chung IY

  • KMID: 1550795
  • Korean J Immunol.
  • 1999 Mar;21(1):47-53.
It is well known that HL-60 cell, a human promyelocytic line, is differentiated into eosinophil-like cells in the presence of butyric acid, and thus the differentiated HL-60 cells have been...
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Effects of rIFN-gamma on Serum IgE and the Number of Pheripheral Blood Eosinophils in Mice Infected with Paragonimus westermani

Shin MH

OBJECTIVE: Elevated serum lgE and pheripheral blood eosinophilia are immunologic hallmark in helminthic infections. Recently, these responses are known to be regulated by Th2-specific cytokine IL-4 and IL-5, respectively. And...
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The role of dependent pathway in eosinophil apoptosis

Ki SY, Jeon KW, Lee MR, Uh ST, Kim YH, Park CS, Chung IY

  • KMID: 2286031
  • J Asthma Allergy Clin Immunol.
  • 1999 Oct;19(5):667-684.
BACKGROUND: Interleukin-5 (IL-5), IL-3, and GM-CSF are known to prolong the survival of eosinophils, and IL-5 has the most potent effect on eosinophil survivaL It is also known that divergent signals induce...
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The Role of Cyclosporine and Mycophenolate in an Orthotopic Porcine-to-Rat Corneal Xenotransplantation

Lee HI, Kim MK, Oh JY, Ko JH, Lee HJ, Wee WR, Lee JH

We performed this study to investigate the feature of rejection in porcine-to-rat corneal orthotopic transplantation and to evaluate the effect of cyclosporine and mycophenolate on the xeno-rejection. Orthotopic corneal transplantation...
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Immunologic Response of Upper and Lower Airway Disease Patients Against Airborne Fungal Cultural Extracts

Shin SH, Ye MK, Kim KY

  • KMID: 2276751
  • Korean J Otolaryngol-Head Neck Surg.
  • 2007 May;50(5):416-419.
BACKGROUND AND OBJECTIVES: Allergic rhinitis, sinusitis and asthma are linked by epidemiologic, physiologic, and immunopathologic characteristics and by similar therapeutic approach. They have clinical manifestations of a systemic inflammatory process...
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Effects of Nasal Instillation of Staphylococcal Enterotoxin B on Nasal and Bronchial Mucosa in BALB/c Mouse

Jin SY, Kim EH, Lee GH, Park YK, Kim YM, Rha KS

  • KMID: 2297606
  • J Rhinol.
  • 2011 May;18(1):35-42.
BACKGROUND AND OBJECTIVES: The effect of nasal exposure to staphylococcal enterotoxin in the pathogenesis of allergic rhinitis remains controversial. We sought to determine the effect of increasing doses of intranasally...
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Differences in airway inflammation according to atopic status in patients with chronic rhinitis

Kwon JW, Kim TW, Kim KM, Jung JW, Cho SH, Min KU, Kim YY, Park HW

BACKGROUND: Chronic rhinitis is a heterogeneous group of diseases that cause nasal inflammation. And the nose may be a window into the lung in the concept of "one airway one...
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Increases in IFN-gamma during the Chronic Asymptomatic Phase in Patients with Asthma

  • KMID: 2234222
  • Korean J Asthma Allergy Clin Immunol.
  • 2004 Dec;24(4):377-384.
BACKGROUND AND OBJECTIVE: Previous studies, during acute asthma exacerbations, have suggested roles for the Th2 cytokines in promoting airway inflammation in asthma patients. We assessed mediators of airway inflammation during...
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Therapeutic Effects of Mycobacterial Secretory Proteins Against Established Asthma in BALB/c Mice

Han ER, Choi IS, Choi HG, Kim HJ

PURPOSE: Live/killed mycobacteria and culture supernatants can suppress asthmatic reactions. This study investigated whether mycobacterial secretory proteins have therapeutic effects on asthma. METHODS: Mycobacterium bovis bacille Calmette-Guerin (BCG; 2x105 CFUs) and...
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Effects of Diesel Exhaust Particles on Airway Responsiveness and Remodeling in a Murine Asthma Model

  • KMID: 2299641
  • Korean J Asthma Allergy Clin Immunol.
  • 2006 Mar;26(1):70-77.
BACKGROUND: Epidemiologic and clinical investigations have suggested a strong link between particulate air pollution and asthma. The purpose of this study was to evaluate an effects of air pollutants on...
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