- A Study of Production of Interleukin-1alpha by Peripheral Lymphocytes in Patients with Coronary Artery Disease
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Park IS, Jeon DS, Choi KB, Hong SJ
- KMID: 2029384
- Korean Circ J.
- 1994 Aug;24(4):595-601.
- doi: 10.4070/kcj.1994.24.4.595
BACKGROUND: Interleukin-1alpha is interesting lymphokine to cardiologists because it has been implicated as a regulatory protein in the development and clinical sequale of atherosclerosis, including the modulation of low density... -
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- The Effect of Interleukin-1alpha on Trabecular Outflow Resistance in Rat Eyes
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Kee C, Seo KM
- KMID: 2205233
- J Korean Ophthalmol Soc.
- 1997 Sep;38(9):1595-1599.
It was investigated if regulation of the trabecular extracellular matrix tumover rate and remodeling plays an important role in decreasing outflow resistance by determining the effect of intracamerally given interleukin-1alpha... -
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- FSL-1, a Toll-like Receptor 2/6 Agonist, Induces Expression of Interleukin-1alpha in the Presence of 27-hydroxycholesterol
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Heo W, Kim SM, Eo SK, Rhim BY, Kim K
- KMID: 2285549
- Korean J Physiol Pharmacol.
- 2014 Dec;18(6):475-480.
- doi: 10.4196/kjpp.2014.18.6.475
We investigated the question of whether cholesterol catabolite can influence expression of inflammatory cytokines via Toll-like receptors (TLR) in monocytic cells. Treatment of THP-1 monocytic cells with 27-hydroxycholesterol (27OHChol) resulted... -
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- Cigarette Smoke-Induced Interleukin-1 Alpha May Be Involved in the Pathogenesis of Adult Acne
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Yang YS, Lim HK, Hong KK, Shin MK, Lee JW, Lee SW, Kim NI
- KMID: 2265692
- Ann Dermatol.
- 2014 Feb;26(1):11-16.
- doi: 10.5021/ad.2014.26.1.11
BACKGROUND: Lipid peroxide (LPO) in comedones, which are produced as a result of sebum oxidation, might potentially induce interleukin-1alpha (IL-1alpha) and exacerbate comedogenesis and inflammatory changes in comedones. OBJECTIVE: To investigate... -
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- Gene Regulatory Regions Required for beta Defensin-2 Up-Regulation by Interleukin-1alpha in the Human Middle Ear Epithelial Cell Line
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Kim HJ, Bae JH, Choung YH, Park K, Moon SK
- KMID: 1597332
- Korean J Otolaryngol-Head Neck Surg.
- 2005 May;48(5):577-581.
BACKGROUND AND OBJECTIVES: Innate immunity is important in the middle ear because of the lack of immune cells in the region. Among innate immunities beta-defensin-2 is known to play an... -
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- Development of an Intervertebral Disc Degeneration Model using Newzealand White Rabbits
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So K, Choi Y, Yoon D, Ryu J, Johnstone , Yoo JU
- KMID: 1447994
- J Korean Soc Spine Surg.
- 2011 Dec;18(4):179-185.
- doi: 10.4184/jkss.2011.18.4.179
STUDY DESIGN: An experimental animal study. OBJECTIVES: To create a more appropriate disc degeneration model which shows how Interleukin 1alpha may induce the activation of metalloproteinases within the nucleus pulposus. SUMMARY OF... -
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- Gene Microarray Related with Apoptosis in Diabetic OLETF Keratocytes
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Lee JE, Kim HS, Lee JS
- KMID: 2337383
- J Korean Ophthalmol Soc.
- 2006 May;47(5):818-827.
PURPOSE: This study was to identified differentiated genes concerned with apoptosis that are up-regulated or down-regulated in OLETF corneal keratocytes stimulated with interleukin-1alpha. METHODS: Otsuka Long Evans Tokushima Fatty (OLETF) corneal... -
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- In Vitro Effects of 1,25-Dihydroxyvitamin D3 on the Production of Interleukin-1alpha by Ultraviolet B Irradiation in Cultured Human Keratinocyte Cell Line HaCaT Cells
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Chi DH, Lim YS, Jang KA, Sung HT, Yeo UC, Sung KJ, Choi JH
- KMID: 2251051
- Korean J Dermatol.
- 2001 Feb;39(2):127-138.
BACKGROUND: Keratinocyte-derived interleukin-1(IL-1)alpha is one of the key cytokines in initiation of cutaneous inflammation. Release of IL-1alpha from human keratinocytes may be induced by proinflammatory stimuli including ultraviolet B(UVB) irradiation,... -
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- Cytokine Gene Expression Associated with Bone Destruction in Cholesteatoma Tissues
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Park CW, Jang YH, Yu YH, Ahn MJ
- KMID: 2074347
- Korean J Otolaryngol-Head Neck Surg.
- 1999 Feb;42(2):159-163.
BACKGROUND AND OBJECTIVES: Cholesteatoma is composed of hyperproliferative keratinizing epithelium in the middle ear cavity. Although the mechanism of bone destruction by cholesteatoma has not been fully elucidated, it has... -
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- Production of Interleukin-1alpha and Tumor Necrosis Factor-alpha by Human Cord and Adult Blood Mononuclear Cells Stimulated by TSST-1 and LPS
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Park EA, Kim KH, Kim GH
- KMID: 2335242
- J Korean Pediatr Soc.
- 1997 May;40(5):690-700.
PURPOSE: Immature immunological defens mechanism in the neonate may contribute to the high susceptibility to overwhelming sepsis. S. aureus TSST-1 and E. coli LPS known as one of the important... -
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- Effect of Apocynin on Acute Lung Injury in Rats Given Interleukin-1alpha Intratracheally
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Lee YM
- KMID: 2319532
- Tuberc Respir Dis.
- 2011 Jun;70(6):482-489.
BACKGROUND: Based on the assertion that apocynin diminishes acute lung injury (ALI) by inhibition of NADPH oxidase, the effect of apocynin was tested in interleukin-1alpha (IL-1)-induced ALI in rats. METHODS: IL-1... -
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- Role of IL-1alpha in Cisplatin-Induced Acute Renal Failure in Mice
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Lee JW, Nam WJ, Han MJ, Shin JH, Kim JG, Kim SH, Kim HR, Oh DJ
- KMID: 1776591
- Korean J Intern Med.
- 2011 Jun;26(2):187-194.
- doi: 10.3904/kjim.2011.26.2.187
BACKGROUND/AIMS: For unknown reasons, caspase-1 -/- mice, protected against cisplatin-induced acute renal failure (ARF), are deficient in interleukin (IL)-1alpha. We thus asked whether IL-1alpha deficiency underlies the mechanism of protection... -
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- Expression of beta Defensins in the Human Middle Ear Mucosa
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Moon SK, Lim DJ
- KMID: 2276095
- Korean J Otolaryngol-Head Neck Surg.
- 2004 Feb;47(2):103-107.
BACKGROUND AND OBJECTIVES: It is believed that the innate immunity plays a critical role in protecting the tubotympanum from being infected because the middle ear cavity is normally sterile despite... -
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- A study for time sequential expression of IL-1 alphaand IL-6 after irradiation on rat lung
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Chang KY, Son CH, Yang DK, Kim KH, Lee H, Youn SM, Yang KM, Hur WJ, Roh MS, Jeong JS, Han JY, Lee KN, Choi PJ, Lee SK, Choi IS, Park SK
- KMID: 2252894
- Korean J Med.
- 2002 Apr;62(4):453-464.
BACKGROUND: One of the limitation during the irradiation of malignant tumor is hazard to normal tissue although it is important and effective tool for treating malignant tumor. We studied the... -
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- Generation of inflammatory cytokines and anaphylatoxins in whole blood under normal blood banking condition
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Ki CS, Koo HH, Jung HL, Oh DJ, Kim DW
- KMID: 2069263
- Korean J Blood Transfus.
- 1998 Dec;9(2):227-233.
BACKGROUND: Several recent studies have reported that generation of inflammatory cytokines and activation of complements may be associated with febrile nonhemolytic transfusion reactions (FNHTR). However, few data are available for... -
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- Cardiopulmonary Bypass-induced Gene Expressions of Proinflammatory Cytokines and Chemokines
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Yu JH, Jo EK, Park JK, Kang SK, Na MH, Lim SP, Lee Y
- KMID: 1915665
- Korean J Thorac Cardiovasc Surg.
- 2002 Feb;35(2):118-126.
BACKGROUND: Cardiopulmonary bypass(CPB) induces the productions of several inflammatory mediators that may be implicated in postoperative organ dysfunction, a problem to which the pediatric population is particularly prone. The purpose... -
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- Microarray Analysis for Genes Associated with Angiogenesis in Diabetic OLETF Keratocytes
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Park JM, Park YM, Jung W, Lee JE, Lee JS
- KMID: 1789986
- J Korean Med Sci.
- 2014 Feb;29(2):265-271.
- doi: 10.3346/jkms.2014.29.2.265
The purpose of this study was to identify the differences in angiogenesis gene expression between normal and diabetic keratocytes stimulated with interleukin-1alpha (IL-1alpha) and tumor necrosis factor-alpha (TNF-alpha). Primarily cultured... -
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- Inhibitory Effects of Actinomycin-D and Pentoxifylline on the Production of IL-1alpha and TNF-alpha by Human Cord and Adult Blood Mononuclear Cells
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Park EA, Kim KH, Kim GH
- KMID: 2104452
- J Korean Pediatr Soc.
- 1998 Dec;41(12):1700-1708.
PURPOSE: An area of intense intrest is assessment of new therapeutic modalities that regulate the inflammatory response in acute bacterial infection is proving to be an area of interest these... -
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- The Induction of Apoptosis by Fas Antibody, IFN - delta, IL - 1 alpha in Normal Human Keratinocytes and KB cells
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Lee HK, Whang KU, Park YL, Kim YK, Norris DA
- KMID: 2230637
- Korean J Dermatol.
- 1997 Apr;35(2):273-278.
BACKGROUND: The Fas antigen is a cell surface molecule that mediates apoptosis in many cell types. Matsues group indicated that keratinocytes constitutively express the Fas antigen and apoptosis was induced... -
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- Pityrosporum ovale Modulate the Pro-inflammatory Cytokines in Normal Human Keratinocyte
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Moon HJ, Lee JB, Kim SJ, Lee SC, Won YH
- KMID: 2086738
- Korean J Dermatol.
- 2003 Nov;41(11):1448-1454.
BACKGROUNDS: Pityrosporum (P.) ovale is a member of the cutaneous microflora, and is associated with several dermatologic diseases. Little is known about the mechanism by which P. ovale causes these... -
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