- Tumor Cell Clone Expressing the Membrane-bound Form of IL-12p35 Subunit Stimulates Antitumor Immune Responses Dominated by CD8+ T Cells
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Lim H, Do SA, Park SM, Kim YS
- KMID: 1431927
- Immune Netw.
- 2013 Apr;13(2):63-69.
- doi: 10.4110/in.2013.13.2.63
IL-12 is a secretory heterodimeric cytokine composed of p35 and p40 subunits. IL-12 p35 and p40 subunits are sometimes produced as monomers or homodimers. IL-12 is also produced as a... -
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- The association study on infection of Mycobacterium leprae and RIPK2
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Kim BC, Kang TJ, Chae GT
- KMID: 1921046
- Korean Lepr Bull.
- 2003 Dec;36(2):23-29.
Receptor-interacting serine/threonine kinase 2(RIPK2) is an adaptor molecule involved in the signal pathway of TLRs. However, there is no report on association between RIPK2 expression and infectious disease including... -
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- Regulation of Cytokine Gene Expression in Nasal Polyp
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Kim CN, Hong SK, Kim MJ, Hong YS
- KMID: 2275867
- Korean J Otolaryngol-Head Neck Surg.
- 2002 Feb;45(2):137-143.
BACKGROUND AND OBJECTIVES: The etiology and pathogenesis of nasal polyp are still ill-defined and have been debated for many years. Recently, the identification and localization of mRNA of cytokines, chemokines,... -
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- The Modulation of IL-12 by Phosphodiesterase IV Inhibitor and Subsequent Changes of Th-1, Th-2 Cytokines in Human Endometrial Tissue
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Park WI, Kim EK, Ko DS, Hong SY, Na JY, Shin JH, Kim DW
- KMID: 2272121
- Korean J Obstet Gynecol.
- 2003 Aug;46(8):1500-1509.
OBJECTIVE: To assess the capability of phosphodiesterase type IV inhibitor (rolipram) to suppress IL-12 in human decidua and the subsequent changes of Th-2 cytokine (IL-10) and Th-1 cytokine (TNF-alpha). METHODS: Decidual... -
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- Gene Expression Analysis of Inflammatory Cytokines in Korean Psoriatic Patients
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Chun JH, Yoon YH, Choe YB, Kang LH, Paik SY, Park CJ
- KMID: 2388939
- Ann Dermatol.
- 2017 Aug;29(4):422-426.
- doi: 10.5021/ad.2017.29.4.422
BACKGROUND: Although phenotypic heterogeneity of psoriasis is suggested by the alternate activation of either T-helper (Th)1-related or Th17-related cytokines, little is known about the mRNA levels of inflammatory cytokines. OBJECTIVE: To... -
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- Mycobacterium tuberculosis ESAT6 Drives the Activation and Maturation of Bone Marrow-Derived Dendritic Cells via TLR4-Mediated Signaling
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Jang AR, Kim G, Hong JJ, Kang SM, Shin SJ, Park JH
- KMID: 2444161
- Immune Netw.
- 2019 Apr;19(2):e13.
- doi: 10.4110/in.2019.19.e13
6-kDa early secretory antigenic target (ESAT6), a virulent factor of Mycobacterium tuberculosis, is involved in immune regulation. However, the underlying mechanism behind the activation and maturation of dendritic cells (DCs)... -
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- Tissue and Serum Inflammatory Cytokine Levels in Korean Psoriasis Patients: A Comparison between Plaque and Guttate Psoriasis
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Roh NK, Han SH, Youn HJ, Kim YR, Lee YW, Choe YB, Ahn KJ
- KMID: 2157451
- Ann Dermatol.
- 2015 Dec;27(6):738-743.
- doi: 10.5021/ad.2015.27.6.738
BACKGROUND: The phenotypic heterogeneity of psoriasis could be explained by the alternate activation of either T-helper (Th)-1- or Th-17-related cytokines. However, evidence directly supporting this hypothesis is scarce. OBJECTIVE: To characterize... -
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- GSK3beta Inhibitor Peptide Protects Mice from LPS-induced Endotoxin Shock
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Ko R, Jang HD, Lee SY
- KMID: 2150666
- Immune Netw.
- 2010 Jun;10(3):99-103.
- doi: 10.4110/in.2010.10.3.99
BACKGROUND: Glycogen synthase kinase 3beta (GSK3beta) is a ubiquitous serine/threonine kinase that is regulated by serine phosphorylation at 9. Recent studies have reported the beneficial effects of a number of... -
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- Epigallocatechin-3-gallate Inhibits LPS-Induced NF-kappaB and MAPK Signaling Pathways in Bone Marrow-Derived Macrophages
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Joo SY, Song YA, Park YL, Myung E, Chung CY, Park KJ, Cho SB, Lee WS, Kim HS, Rew JS, Kim NS, Joo YE
- KMID: 2284263
- Gut Liver.
- 2012 Apr;6(2):188-196.
BACKGROUND/AIMS: Epigallocatechin-3-gallate (EGCG), the primary catechin in green tea, has anti-inflammatory and anti-oxidative properties. The aim of the current study was to characterize the impact of EGCG on lipopolysaccharide (LPS)-induced... -
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- Characterization of Immune Responses to Mycobacterium tuberculosis Rv2041c Protein
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Kim SY, Shin AR, Lee BS, Kim HJ, Jeon BY, Cho SN, Park JK, Shin SJ
- KMID: 1474161
- J Bacteriol Virol.
- 2009 Sep;39(3):183-193.
- doi: 10.4167/jbv.2009.39.3.183
Tuberculosis, which is caused by Mycobacterium tuberculosis (M. tb), is one of the most important infectious diseases in the world. Although many functional studies have been conducted on M. tb... -
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