- Performance Evaluation of a New Automated Chemiluminescent Immunoanalyzer-Based Interferon-Gamma Releasing Assay AdvanSure I3 in Comparison With the QuantiFERON-TB Gold In-Tube Assay
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Kim JJ, Park Y, Choi D, Kim HS
- KMID: 2457491
- Ann Lab Med.
- 2020 Jan;40(1):33-39.
- doi: 10.3343/alm.2020.40.1.33
BACKGROUND: The interferon-gamma (IFN-γ) releasing assay (IGRA) is widely used for latent tuberculosis infection (LTBI) diagnosis. We evaluated the analytical performance of a new automated chemiluminescent immunoanalyzer-based IGRA (CLIA-IGRA), AdvanSure... -
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- Screening and Treatment of Latent Tuberculosis Infection among Healthcare Workers at a Referral Hospital in Korea
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Park SY, Lee E, Lee EJ, Kim TH, Kim YK
- KMID: 2466468
- Infect Chemother.
- 2019 Dec;51(4):355-364.
- doi: 10.3947/ic.2019.51.4.355
BACKGROUND: Healthcare workers (HCWs) have a high risk of tuberculosis (TB) infection. Since August 2017, Korea has mandated the testing of latent TB infection (LTBI) and recommended treatment from HCWs... -
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- Analysis of Prevalence and Risk Factors for Latent Tuberculosis Infection among Healthcare Workers
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Lee JB, Choi JS
- KMID: 2469271
- J Korean Biol Nurs Sci.
- 2019 Nov;21(4):300-307.
- doi: 10.7586/jkbns.2019.21.4.300
PURPOSE: The purpose of this study was to provide basic data on the infection prevention management program, which is one of the infectious disease control program by identifying the prevalence... -
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- Inhibition of miRNA-222-3p Relieves Staphylococcal Enterotoxin B-Induced Liver Inflammatory Injury by Upregulating Suppressors of Cytokine Signaling 1
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Zhang P, Yu J, Gui Y, Sun C, Han W
- KMID: 2460227
- Yonsei Med J.
- 2019 Nov;60(11):1093-1102.
- doi: 10.3349/ymj.2019.60.11.1093
PURPOSE: Staphylococcal enterotoxin B (SEB) has been well-documented to induce liver injury. miRNA-222-3p (miR-222-3p) was implicated in SEB-induced lung injury and several liver injuries. This study aimed to explore the... -
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- Good Agreement between an Interferon Gamma Release Assay and Tuberculin Skin Tests in Testing for Latent Tuberculosis Infection among HIV-Infected Patients in Indonesia
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Reviono R, Saptawati , Redhono D, Suryawati
- KMID: 2460035
- J Korean Med Sci.
- 2019 Oct;34(40):e259.
- doi: 10.3346/jkms.2019.34.e259
BACKGROUND: Latent tuberculosis infection is a condition where there is a persistent immune response to Mycobacterium tuberculosis without clinical manifestations of tuberculosis. Currently, there is no gold standard to diagnose... -
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- Experiences of Latent Tuberculosis Infection Treatment for the North Korean Refugees
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Kim BK, Kim HJ, Kim HJ, Cha JH, Lee JB, Jeon J, Kim CY, Kim Y, Kim JH, Shin C, Lee SH
- KMID: 2459054
- Tuberc Respir Dis.
- 2019 Oct;82(4):306-310.
- doi: 10.4046/trd.2019.0034
BACKGROUND: Tuberculosis (TB) is increasing in immigrants. We aimed to investigate the current status of latent tuberculosis infection (LTBI) treatment for North Korean Refugees (NKR) compared to South Koreans Contacts... -
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- Distinct Inflammation Biomarkers in Healthy Individuals and Patients with Schizophrenia: A Reliability Testing of Multiplex Cytokine Immunoassay by Bland-Altman Analysis
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Yeh TC, Chu HT, Tsai CK, Chang HA, Yang FC, Huang SY, Liang CS
- KMID: 2456171
- Psychiatry Investig.
- 2019 Aug;16(8):607-614.
- doi: 10.30773/pi.2019.04.14
OBJECTIVE: Since the inflammatory process has been implicated in the pathophysiology of psychiatric disorder, an important issue emerging is to assess the test-retest reliability of cytokine measurement in healthy individuals... -
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- Proposal to Revise the Screening Test for Latent Tuberculosis Infection in Close Contacts at Elementary Schools in Korea
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Bae JM
- KMID: 2455132
- J Prev Med Public Health.
- 2019 Jul;52(4):272-275.
- doi: 10.3961/jpmph.19.043
The 2018 National Guideline for Tuberculosis Control, which was published by the Korea Centers for Diseases Prevention and Control (KCDC), mandates conducting an epidemiological survey among close contacts of active... -
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- Neopterin Levels and Indoleamine 2,3-Dioxygenase Activity as Biomarkers of Immune System Activation and Childhood Allergic Diseases
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Ünüvar S, Erge D, Kılıçarslan B, Gözükara Bağ HG, Çatal F, Girgin G, Baydar T
- KMID: 2431606
- Ann Lab Med.
- 2019 May;39(3):284-290.
- doi: 10.3343/alm.2019.39.3.284
BACKGROUND: Although Th2 immune activation is predominant in allergic diseases, neopterinlevels and indoleamine 2,3-dioxygenase (IDO)-1 activity (kynurenine:tryptophan ratio), which reflect Th1 immune activity, increase with interferon-gamma (IFN-γ) stimulation. We investigated... -
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- The Performance of the Agility System for Interferon Gamma Release Assay Using QuantiFERON TB Gold In-Tube Assay
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Seok K, Shin S
- KMID: 2446696
- J Lab Med Qual Assur.
- 2019 Mar;41(1):29-38.
- doi: 10.15263/jlmqa.2019.41.1.29
BACKGROUND: As stated in ‘The Action Strategy for Tuberculosis-Free Korea,’ last March, high-throughput, large-scale analytical instruments for interferon gamma release assays (IGRA) are demanded by many clinical laboratories using the... -
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- Diagnosis and treatment of latent tuberculosis infection
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Min J, Kim JS
- KMID: 2431990
- J Korean Med Assoc.
- 2019 Jan;62(1):11-17.
- doi: 10.5124/jkma.2019.62.1.11
In order to eliminate tuberculosis worldwide by 2050, effective management of latent tuberculosis infection is essential, and policy-makers have begun to recognize the importance of scaling up preventive therapy. The... -
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- Diagnosis and Treatment of Latent Tuberculosis Infection: The Updated 2017 Korean Guidelines
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Lee SH
- KMID: 2438041
- Korean J Med.
- 2018 Dec;93(6):509-517.
- doi: 10.3904/kjm.2018.93.6.509
A small number of viable tuberculosis bacilli can reside in an individual with latent tuberculosis infection (LTBI) without obvious clinical symptoms or abnormal chest radiographs. Diagnosis and treatment of LTBI... -
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- Systemic review: agreement between the latent tuberculosis screening tests among patients with rheumatic diseases
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Pyo J, Cho SK, Kim D, Sung YK
- KMID: 2426409
- Korean J Intern Med.
- 2018 Nov;33(6):1241-1251.
- doi: 10.3904/kjim.2016.222
BACKGROUND/AIMS: To estimate the level of agreement and positivity rates of latent tuberculosis infection (LTBI) tests prior to the use of tumor necrosis factor (TNF) inhibitors in relation to underlying... -
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- Incidence of Active Tuberculosis within One Year after Tumor Necrosis Factor Inhibitor Treatment according to Latent Tuberculosis Infection Status in Patients with Inflammatory Bowel Disease
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Kang J, Jeong DH, Han M, Yang SK, Byeon JS, Ye BD, Park SH, Hwang SW, Shim TS, Jo KW
- KMID: 2426354
- J Korean Med Sci.
- 2018 Nov;33(47):e292.
- doi: 10.3346/jkms.2018.33.e292
BACKGROUND: We investigated the incidence of active tuberculosis among patients with inflammatory bowel disease (IBD) treated with tumor necrosis factor (TNF) inhibitors, with or without latent tuberculosis infection (LTBI). METHODS: The... -
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- High risk of tuberculosis during infliximab therapy despite tuberculosis screening in inflammatory bowel disease patients in India
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Agarwal A, Kedia S, Jain S, Gupta V, Bopanna S, Yadav DP, Goyal S, Mouli VP, Dhingra R, Makharia G, Ahuja V
- KMID: 2434161
- Intest Res.
- 2018 Oct;16(4):588-598.
- doi: 10.5217/ir.2018.00023
BACKGROUND/AIMS: The data on the risk of tuberculosis (TB) reactivation with infliximab (IFX) in patients with inflammatory bowel disease (IBD) from TB endemic countries, like India, is limited. The risk... -
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- Direct Antiviral Mechanisms of Interferon-Gamma
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Kang S, Brown HM, Hwang S
- KMID: 2424199
- Immune Netw.
- 2018 Oct;18(5):e33.
- doi: 10.4110/in.2018.18.e33
Interferon-gamma (IFNG) is a pleiotropic cytokine that modulates both innate and adaptive immune networks; it is the most potent activator of macrophages and a signature cytokine of activated T lymphocytes.... -
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- Thapsigargin Increases IL-2 Production in T Cells at Nanomolar Concentrations
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Kim KH, Kim SH, Jung HH, Moon JH, Jeong SU, Yu K, Lee CK
- KMID: 2419771
- Immune Netw.
- 2018 Aug;18(4):e26.
- doi: 10.4110/in.2018.18.e26
Thapsigargin (TGN) is a potent and selective inhibitor of sarco-endoplasmic Ca²âº-ATPase, leading to rapid elevation of cytoplasmic Ca2+ concentration. Previous reports have shown that TGN increases the production of various... -
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- Decreased IL-1ra and NCAM-1/CD56 Serum Levels in Unmedicated Patients with Schizophrenia Before and After Antipsychotic Treatment
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Chu CS, Li DJ, Chu CL, Wu CC, Lu T
- KMID: 2428837
- Psychiatry Investig.
- 2018 Jul;15(7):727-732.
- doi: 10.30773/pi.2017.11.10
OBJECTIVE: Schizophrenia (SZ) has been associated with the inflammatory-related and immunological pathogenesis. This study investigates the aberration of cytokines in patients with SZ. METHODS: Thirty patients with SZ without antipsychotic treatment... -
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- Diagnosis, Treatment and Clinical Features of Cutaneous Leishmaniasis in Saudi Arabia
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Hawash YA, Ismail KA, Abdel-Wahab MM, Khalifa M
- KMID: 2416353
- Korean J Parasitol.
- 2018 Jun;56(3):229-236.
- doi: 10.3347/kjp.2018.56.3.229
Cutaneous leishmaniasis (CL) has been one of the most common parasitic diseases in Saudi Arabia. This study exhibits the clinical features, diagnosis, cytokine profile and treatment of CL patients in... -
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- Association between endotoxin levels in dust from indoor swine housing environments and the immune responses of pigs
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Roque K, Shin KM, Jo JH, Lim GD, Song ES, Shin SJ, Gautam R, Lee JH, Kim YG, Cho AR, Kim CY, Kim HJ, Lee MS, Oh HG, Lee BC, Kim JH, Kim KH, Jeong HK, Kim HA, Heo Y
- KMID: 2412123
- J Vet Sci.
- 2018 May;19(3):331-338.
- doi: 10.4142/jvs.2018.19.3.331
Indoor animal husbandry environments are inevitably contaminated with endotoxins. Endotoxin exposure is associated with various inflammatory illnesses in animals. This cross-sectional study evaluated the relationship between the degree of endotoxin... -
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