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Goals of Treatment, Indication, and Treatment for Chronic Hepatits C

Paik SW

  • KMID: 1767541
  • Korean J Gastroenterol.
  • 2008 Jun;51(6):368-371.
Hepatitis C virus (HCV) is a major cause of chronic hepatitis and hepatic fibrosis worldwide. Up to 85% of individuals infected with HCV develop chronic infection, which can progress to...
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A case report of treatment with pegylated interferon alpha for lamivudine-resistant chronic hepatitis B virus infection

Hur WH, Woo HY, Jeong SW, You CR, Bae SH, Choi JY, Yoon SK

The wide use of lamivudine in chronic hepatitis B has produced a monotonic increase in patients with lamivudine resistance. Therefore, treating lamivudine resistance in chronic hepatitis B is a major...
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Durability of Sustained Virologic Response in Chronic Hepatitis C: Analysis of Factors Related to Relapse after Sustained Virologic Response with Peginterferon Plus Ribavirin Combination Therapy

Lee JE, Yoon NR, Kim JD, Song MJ, Kwon JH, Bae SH, Choi JY, Jeong SW, Yoon SK

BACKGROUND/AIMS: Pegylated interferon plus ribavirin combination therapy has been the standard of therapy for patients with chronic hepatitis C. Although previous studies have reported long term durability after the sustained...
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Durability of a sustained virologic response in combination therapy with interferon/peginterferon and ribavirin for chronic hepatitis C

Kim CH, Park BD, Lee JW, Kim YS, Jeong S, Lee DH, Kim HG, Shin YW, Kwon KS, Lee JI

BACKGROUNDS/AIMS: The ultimate goal of antiviral therapy using interferon/pegylated interferon combined with ribavirin in chronic C-viral hepatitis is to achieve a sustained virologic response (SVR). Several studies have shown that...
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Mutations within the interferon sensitivity determining region in Korean patients infected with hepatitis C virus genotype 1b

Jin YJ, Park YK, Yun GJ, Lee HC, Jeong SH, Kim GM, Lim YS, Chung YH, Lee YS, Suh DJ

BACKGROUND/AIMS: The treatment response to interferon could differ with mutations in the interferon-sensitivity-determining region (ISDR) in patients infected with hepatitis C virus (HCV) genotype-1b (HCV-Ib). We examined the pattern of...
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Impact of adherence to peginterferon-ribavirin combination therapy in chronic hepatitis C patients on achieving a sustained virologic response

Jeong SW, Kim JD, Woo HY, You CR, Lee SW, Song MJ, Jang JW, Bae SH, Choi JY, Yoon SK

BACKGROUND/AIMS: Various predictive factors for peginterferon alpha and ribavirin therapy in chronic hepatitis C have been reported, but the effect of adherence to therapy has not been established. We investigated...
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Importance of Medication Adherence to Peginterferon-Ribavirin Combination Therapy in Patients with Chronic Hepatitis C

Goh PG, Kim MJ, Kim HJ, Eun HS, Kim ES, Kim YJ, Lee SY, Moon HS, Lee ES, Kim SH, Lee BS, Lee HY

BACKGROUND/AIMS: The combination therapy with peginterferon and ribavirin is a standard treatment for patients with chronic hepatitis C. However, because of the long duration of the treatment and many complications,...
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