Korean J Gastroenterol.  2008 Jun;51(6):368-371.

Goals of Treatment, Indication, and Treatment for Chronic Hepatits C

Affiliations
  • 1Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. sw.paik@samsung.com

Abstract

Hepatitis C virus (HCV) is a major cause of chronic hepatitis and hepatic fibrosis worldwide. Up to 85% of individuals infected with HCV develop chronic infection, which can progress to cirrhosis and hepatocellular carcinoma. The primary goal in the treatment of HCV infection is to reduce the mortality by preventing liver-related deaths associated with the development of hepatocellular carcinoma and decompensated cirrhosis. Pegylated interferons together with ribavirin are currently the standard of care for patients with chronic hepatitis. Here, I discuss the goals of treatment, indication and treatment of chronic hepatitis C.

Keyword

Hepatitis C; Pegylated interferon; Ribavirin

MeSH Terms

Antiviral Agents/*therapeutic use
Drug Therapy, Combination
Hepatitis C, Chronic/diagnosis/*drug therapy
Humans
Interferon Alfa-2a/*therapeutic use
Interferon Alfa-2b/*therapeutic use
Polyethylene Glycols/*therapeutic use
Ribavirin/*therapeutic use
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