- Molecular Mechanism of Insulin Resistance in Obesity and Type 2 Diabetes
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Choi K, Kim YB
- KMID: 1785667
- Korean J Intern Med.
- 2010 Jun;25(2):119-129.
- doi: 10.3904/kjim.2010.25.2.119
Insulin resistance is a major risk factor for developing type 2 diabetes caused by the inability of insulin-target tissues to respond properly to insulin, and contributes to the morbidity of... -
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- Insulin resistance as a key link for the increased risk of cognitive impairment in the metabolic syndrome
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Kim B, Feldman EL
- KMID: 2155414
- Exp Mol Med.
- 2015 Mar;47(3):e149.
- doi: 10.1038/emm.2015.3
Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors that includes obesity, diabetes, and dyslipidemia. Accumulating evidence implies that MetS contributes to the development and progression of Alzheimer's disease... -
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- Obesity and Gastrointestinal Cancer-related Factor
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Kim DJ
- KMID: 1775827
- Korean J Gastroenterol.
- 2012 Jan;59(1):8-15.
- doi: 10.4166/kjg.2012.59.1.8
Despite a higher incidence and less favorable outcome of malignant tumors in obese patients, much less recognized is the link between obesity and cancer. The mechanism of the association of... -
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- Type 2 Diabetes Mellitus and Its Association with the Risk of Pancreatic Carcinogenesis: A Review
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Biadgo B, Abebe M
- KMID: 2373421
- Korean J Gastroenterol.
- 2016 Apr;67(4):168-177.
- doi: 10.4166/kjg.2016.67.4.168
The prevalence of diabetes mellitus (DM) and associated diseases such as cancers are substantially increasing worldwide. About 80% of the patients with pancreatic cancer have glucose metabolism alterations. This suggests... -
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- Hepatic STAMP2 decreases hepatitis B virus X protein-associated metabolic deregulation
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Kim HY, Cho HK, Yoo SK, Cheong J
- KMID: 1506226
- Exp Mol Med.
- 2012 Oct;44(10):622-632.
Six transmembrane protein of prostate 2 (STAMP2) plays a key role in linking inflammatory and diet-derived signals to systemic metabolism. STAMP2 is induced by nutrients/feeding as well as by cytokines... -
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- The regulatory mechanism of phosphatidylinositol 3-kinase by insulin in 3T3 L1 fibroblasts: phosphorylation-independent activation of phosphatidylinositol 3-kinase
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Kang IS, Choi SL, Kim SS, Kim SJ, Ha JH, Oh SM, Kim SS
- KMID: 755019
- Exp Mol Med.
- 1998 Dec;30(4):263-269.
Phosphatidylinositol (PI) 3-kinase plays an important role in transducing the signals of various growth factor receptors. However, the regulatory mechanism of PI3-kinase activity by these growth factor receptors is not... -
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- Immunohistochemical Study of the Pancreatic Endocrine Cells in the BALB/c mice: An Unique Distributional Pattern of Glucagon
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Ku SK, Lee HS, Lee JH
- KMID: 1095117
- J Vet Sci.
- 2002 Sep;3(3):167-173.
The regional distribution and relative frequency of insulin-, glucagon-, somatostatin- and pancreatic polypeptide (PP)-producing endocrine cells in the pancreas of BALB/c mouse were investigated by immunohistochemical method. The pancreas of... -
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- Signaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet beta cells
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Kalwat MA, Thurmond D
- KMID: 2154256
- Exp Mol Med.
- 2013 Aug;45(8):e37.
The maintenance of whole-body glucose homeostasis is critical for survival, and is controlled by the coordination of multiple organs and endocrine systems. Pancreatic islet beta cells secrete insulin in response... -
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- Parameters of Glucose and Lipid Metabolism Affect the Occurrence of Colorectal Adenomas Detected by Surveillance Colonoscopies
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Kim NH, Suh JY, Park JH, Park DI, Cho YK, Sohn CI, Choi K, Jung YS
- KMID: 2427123
- Yonsei Med J.
- 2017 Mar;58(2):347-354.
- doi: 10.3349/ymj.2017.58.2.347
PURPOSE: Limited data are available regarding the associations between parameters of glucose and lipid metabolism and the occurrence of metachronous adenomas. We investigated whether these parameters affect the occurrence of... -
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- An immunohistochemical Study on the Pancreatic Endocrine Cells of the C57BL/6 Mouse
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Ku SK, Lee HS, Lee JH
- KMID: 1097350
- J Vet Sci.
- 2002 Dec;3(4):327-333.
The regional distribution and relative frequency of the pancreatic endocrine cells in the C57BL/6 mouse were studied by immunohistochemical method using four types of specific mammalian antisera against insulin, glucagon,... -
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- Immunohistochemical Study of the Endocrine Cells in the Pancreas of the Carp,Cyprinus carpio (Cyprinidae)
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Kong HS, Lee JH, Park KD, Ku SK, Lee HS
- KMID: 1097347
- J Vet Sci.
- 2002 Dec;3(4):303-314.
The regional distribution and relative frequency of some endocrine cells in the pancreas of the carp, Cyprinus carpio Linnaeus, belonging to the family Cyprinidae in the order Cypriniformes, were observed... -
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- Resveratrol stimulates glucose transport in C2C12 myotubes by activating AMP-activated protein kinase
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Park CE, Kim MJ, Lee JH, Min BI, Bae H, Choe W, Kim SS, Ha J
- KMID: 1094663
- Exp Mol Med.
- 2007 Apr;39(2):222-229.
trans-Resveratrol (t-RVT), a naturally occurring polyphenol found in Polygonum cuspidatum, grape, and red wine, has been reported to have anti- inflammatory, cardioprotective, and cancer chemopreventive properties. However antidiabetic effect of... -
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- Arsenic Exposure and Prevalence of Diabetes Mellitus in Korean Adults
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Rhee SY, Hwang YC, Woo JT, Chin SO, Chon S, Kim YS
- KMID: 2158033
- J Korean Med Sci.
- 2013 Jun;28(6):861-868.
- doi: 10.3346/jkms.2013.28.6.861
It has been suggested that there is an association between environmental, low-level arsenic exposure and the risk of diabetes mellitus (DM), but little research has been conducted. Here, the glucose... -
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- Regulation of Inhibitors of Differentiation Family Proteins by Thyroid-Stimulating Hormone in FRTL-5 Thyroid Cells
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Jo YS, Hwang ES, Lee JH, Lee Y, Kim SY, Choi YS, Bai YS, Hong JH, Kim YJ, Lee IS, Rha SY, Ro HK, Shong M
- KMID: 1713459
- J Korean Med Sci.
- 2008 Apr;23(2):262-269.
- doi: 10.3346/jkms.2008.23.2.262
Members of the inhibitors of differentiation (Id) family of helix-loop-helix (HLH) proteins are known to play important roles in the proliferation and differentiation of many cell types. Thyroid-stimulating hormone (TSH)... -
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