- Neural Mechanisms of Discogenic Back Pain: How Does Nerve Growth Factor Play a Key Role?
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Aoki Y, Ohtori S, Nakagawa K, Nakajima A, Inoue G, Miyagi M, Takahashi
- KMID: 2288444
- Korean J Spine.
- 2011 Jun;8(2):83-87.
- doi: 10.14245/kjs.2011.8.2.83
It was reported that nerve fibers were present in the inner part of lumbar intervertebral discs from patients with discogenic pain. Because there are no nerve fibers in the inner... -
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- No Acceleration of Intervertebral Disc Degeneration after a Single Injection of Bupivacaine in Young Age Group with Follow-Up of 5 Years
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Ohtori S, Inoue G, Orita S, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Nakamura J, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Takaso M, Toyone T, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Takahashi
- KMID: 2270434
- Asian Spine J.
- 2013 Sep;7(3):212-217.
- doi: 10.4184/asj.2013.7.3.212
STUDY DESIGN: Prospective study of changes in intervertebral disc degeneration after injection of bupivacaine. PURPOSE: To examine whether injection of bupivacaine into human intervertebral discs accelerates their degeneration. OVERVIEW OF LITERATURE: Bupivacaine... -
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- Transdermal Fentanyl for Chronic Low Back Pain
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Ohtori S, Inoue G, Orita S, Eguchi Y, Ochiai N, Kishida S, Takaso M, Aoki Y, Kuniyoshi , Nakamura J, Ishikawa T, Arai G, Miyagi M, Kamoda H, Suzuki M, Toyone T, Takahashi
- KMID: 1716879
- Yonsei Med J.
- 2012 Jul;53(4):788-793.
- doi: 10.3349/ymj.2012.53.4.788
PURPOSE: Chronic low back pain is a common clinical problem. As medication, non-steroidal anti-inflammatory drugs are generally used; however, they are sometimes non-effective. Recently, opioids have been used for the... -
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- Interspinous Ligament Lidocaine and Steroid Injections for the Management of Baastrup's Disease: A Case Series
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Okada K, Ohtori S, Inoue G, Orita S, Eguchi Y, Nakamura J, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Toyone T, Yamauchi K, Takahashi
- KMID: 2270344
- Asian Spine J.
- 2014 Jun;8(3):260-266.
- doi: 10.4184/asj.2014.8.3.260
STUDY DESIGN: Prospective study. PURPOSE: To examine the long-term effects of interspinous ligament injections of local anesthetics and steroids for the treatment of Baastrup's diseases. OVERVIEW OF LITERATURE: Baastrup's disease is associated... -
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- Clinical Incidence of Sacroiliac Joint Arthritis and Pain after Sacropelvic Fixation for Spinal Deformity
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Ohtori S, Sainoh T, Takaso M, Inoue G, Orita S, Eguchi Y, Nakamura J, Aoki Y, Ishikawa T, Miyagi M, Arai G, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Yamazaki M, Toyone T, Takahashi
- KMID: 1120211
- Yonsei Med J.
- 2012 Mar;53(2):416-421.
- doi: 10.3349/ymj.2012.53.2.416
PURPOSE: Sacroiliac fixation using iliac screws for highly unstable lumbar spine has been reported with an improved fusion rate and clinical results. On the other hand, there is a potential... -
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- Human Leukocyte Antigens and Biomarkers in Type 1 Diabetes Mellitus Induced by Immune-Checkpoint Inhibitors
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Inaba H, Kaido Y, Ito S, Hirobata T, Inoue G, Sugita T, Yamamoto Y, Jinnin M, Kimura H, Kobayashi T, Iwama S, Arima H, Matsuoka T
- KMID: 2527140
- Endocrinol Metab.
- 2022 Feb;37(1):84-95.
- doi: 10.3803/EnM.2021.1282
Background: Type 1 diabetes mellitus induced by immune-checkpoint inhibitors (ICI-T1DM) is a rare critical entity. However, the etiology of ICI-T1DM remains unclear. Methods: In order to elucidate risk factors for ICI-T1DM,... -
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- Injection of Bupivacaine into Disc Space to Detect Painful Nonunion after Anterior Lumbar Interbody Fusion (ALIF) Surgery in Patients with Discogenic Low Back Pain
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Kimura S, Ohtori S, Orita S, Inoue G, Eguchi Y, Takaso M, Ochiai N, Kuniyoshi , Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Sakuma Y, Kubota G, Oikawa Y, Inage K, Sainoh T, Yamauchi K, Toyone T, Nakamura J, Kishida S, Sato J, Takahashi
- KMID: 2386481
- Yonsei Med J.
- 2014 Mar;55(2):487-492.
PURPOSE: Bupivacaine is commonly used for the treatment of back pain and the diagnosis of its origin. Nonunion is sometimes observed after spinal fusion surgery; however, whether the nonunion causes... -
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- Progressive Change in Joint Degeneration in Patients with Knee or Hip Osteoarthritis Treated with Fentanyl in a Randomized Trial
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Fujii T, Takana K, Orita S, Inoue G, Ochiai N, Kuniyoshi , Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Sakuma Y, Kubota G, Oikawa Y, Inage K, Sainoh T, Sato J, Yamauchi K, Toyone T, Nakamura J, Kishida S, Takahashi , Ohtori S
- KMID: 1799506
- Yonsei Med J.
- 2014 Sep;55(5):1379-1385.
- doi: 10.3349/ymj.2014.55.5.1379
PURPOSE: Opioids improve pain from knee and hip osteoarthritis (OA) and decrease the functional impairment of patients. However, there is a possibility that opioids induce analgesia and suppress the physiological... -
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- Increase of TRPV1-Immunoreactivity in Dorsal Root Ganglia Neurons Innervating the Femur in a Rat Model of Osteoporosis
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Yoshino K, Suzuki M, Kawarai Y, Sakuma Y, Inoue G, Orita S, Yamauchi K, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Kubota G, Oikawa Y, Inage K, Sainoh T, Sato J, Nakamura J, Toyone T, Takahashi , Ohtori S
- KMID: 2070208
- Yonsei Med J.
- 2014 Nov;55(6):1600-1605.
- doi: 10.3349/ymj.2014.55.6.1600
PURPOSE: Transient receptor potential vanilloid 1 (TRPV1) is a ligand-gated nonselective cation channel, which can be activated by capsaicin and other noxious stimuli. Recently, an association between bone pain and... -
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- Classification of Chronic Back Muscle Degeneration after Spinal Surgery and Its Relationship with Low Back Pain
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Ohtori S, Orita S, Yamauchi K, Eguchi Y, Aoki Y, Nakamura J, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Kubota G, Inage K, Sainoh T, Sato J, Shiga Y, Abe K, Fujimoto K, Kanamoto H, Inoue G, Takahashi
- KMID: 2382959
- Asian Spine J.
- 2016 Jun;10(3):516-521.
- doi: 10.4184/asj.2016.10.3.516
STUDY DESIGN: Retrospective case series. PURPOSE: To classify back muscle degeneration using magnetic resonance imaging (MRI) and investigate its relationship with back pain after surgery. OVERVIEW OF LITERATURE: Back muscle injury and... -
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- Evaluation of Lumbar Intervertebral Disc Degeneration Using T1Ï and T2 Magnetic Resonance Imaging in a Rabbit Disc Injury Model
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Ishikawa T, Watanabe A, Kamoda H, Miyagi M, Inoue G, Takahashi , Ohtori S
- KMID: 2410852
- Asian Spine J.
- 2018 Apr;12(2):317-324.
- doi: 10.4184/asj.2018.12.2.317
STUDY DESIGN: An in vivo histologic and magnetic resonance imaging (MRI) study of lumbar intervertebral disc (IVD) degeneration was conducted. PURPOSE: To clarify the sensitivity and efficacy of T1Ï/T2 mapping for... -
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- Perioperative Evaluation of Respiratory Muscle Strength after Scoliosis Correction in Patients with Duchenne Muscular Dystrophy
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Saito W, Mizuno K, Inoue G, Imura T, Nakazawa T, Miyagi M, Shirasawa , Uchida K, Takaso M
- KMID: 2392663
- Asian Spine J.
- 2017 Oct;11(5):787-792.
- doi: 10.4184/asj.2017.11.5.787
STUDY DESIGN: Retrospective cohort study. PURPOSE: To investigate the effect of spinal correction on respiratory muscle strength in patients with Duchenne muscular dystrophy (DMD). OVERVIEW OF LITERATURE: Several studies have reported that... -
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- Do Physical Symptoms Predict the Outcome of Surgical Fusion in Patients with Discogenic Low Back Pain?
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Ohtori S, Orita S, Yamauchi K, Eguchi Y, Aoki Y, Nakamura J, Miyagi M, Suzuki M, Kubota G, Inage K, Sainoh T, Sato J, Shiga Y, Abe K, Fujimoto K, Kanamoto H, Inoue G, Takahashi
- KMID: 2382958
- Asian Spine J.
- 2016 Jun;10(3):509-515.
- doi: 10.4184/asj.2016.10.3.509
STUDY DESIGN: Retrospective case series. PURPOSE: To determine whether symptoms predict surgical outcomes for patients with discogenic low back pain (DLBP). OVERVIEW OF LITERATURE: Specific diagnosis of DLBP remains difficult. Worsening of... -
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- Transient Receptor Potential Vanilloid 1-Immunoreactive Innervation Increases in Fractured Rat Femur
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Kawarai Y, Suzuki M, Yoshino K, Inoue G, Orita S, Yamauchi K, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Sato J, Nakamura J, Takaso M, Toyone T, Takahashi , Ohtori S
- KMID: 1779904
- Yonsei Med J.
- 2014 Jan;55(1):185-190.
- doi: 10.3349/ymj.2014.55.1.185
PURPOSE: Pain from vertebral or femoral neck fractures is a particularly important problem in clinical orthopaedics. Transient receptor potential vanilloid 1 (TRPV1) is a ligand-gated nonselective cation channel, and there... -
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- PainVision Apparatus Is Effective for Assessing Low Back Pain
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Ohtori S, Kawaguchi , Takebayashi T, Orita S, Inoue G, Yamauchi K, Aoki Y, Nakamura J, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Sato J, Takahashi , Konno S
- KMID: 2270221
- Asian Spine J.
- 2014 Dec;8(6):793-798.
- doi: 10.4184/asj.2014.8.6.793
STUDY DESIGN: Case series. PURPOSE: To determine the utility of "PainVision" apparatus for the assessment of low back pain. OVERVIEW OF LITERATURE: A newly developed device, the PainVision PS-2100 (Nipro, Osaka, Japan),... -
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- More than 6 Months of Teriparatide Treatment Was More Effective for Bone Union than Shorter Treatment Following Lumbar Posterolateral Fusion Surgery
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Ohtori S, Orita S, Yamauchi K, Eguchi Y, Ochiai N, Kuniyoshi , Aoki Y, Nakamura J, Miyagi M, Suzuki M, Kubota G, Inage K, Sainoh T, Sato J, Shiga Y, Abe K, Fujimoto K, Kanamoto H, Inoue G, Takahashi
- KMID: 2169329
- Asian Spine J.
- 2015 Aug;9(4):573-580.
- doi: 10.4184/asj.2015.9.4.573
STUDY DESIGN: Retrospective case series. PURPOSE: To examine the most effective duration of teriparatide use for spinal fusion in women with postmenopausal osteoporosis. OVERVIEW OF LITERATURE: We reported that daily subcutaneous injection... -
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- Mini-Open Anterior Retroperitoneal Lumbar Interbody Fusion: Oblique Lateral Interbody Fusion for Lumbar Spinal Degeneration Disease
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Ohtori S, Orita S, Yamauchi K, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Aoki Y, Nakamura J, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Sato J, Fujimoto K, Shiga Y, Abe K, Toyone T, Inoue G, Takahashi
- KMID: 2366348
- Yonsei Med J.
- 2015 Jul;56(4):1051-1059.
- doi: 10.3349/ymj.2015.56.4.1051
PURPOSE: Surgery for lumbar spinal degeneration disease is widely performed. While posterior decompression and fusion are popular, anterior lumbar interbody fusion (ALIF) is also used for treatment. Extreme lateral interbody... -
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- Up-Regulation of Pain Behavior and Glial Activity in the Spinal Cord after Compression and Application of Nucleus Pulposus onto the Sciatic Nerve in Rats
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Norimoto M, Sakuma Y, Suzuki M, Orita S, Yamauchi K, Inoue G, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Kubota G, Oikawa Y, Inage K, Sainoh T, Sato J, Nakamura J, Toyone T, Takahashi , Ohtori S
- KMID: 2270235
- Asian Spine J.
- 2014 Oct;8(5):549-556.
- doi: 10.4184/asj.2014.8.5.549
STUDY DESIGN: Experimental animal study. PURPOSE: To evaluate pain-related behavior and changes in glial activity in the spinal dorsal horn after combined sciatic nerve compression and nucleus pulposus (NP) application in... -
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- Efficacy of Combination of Meloxicam and Pregabalin for Pain in Knee Osteoarthritis
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Ohtori S, Inoue G, Orita S, Takaso M, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzkuki M, Nakamura J, Kubota G, Sakuma Y, Oikawa Y, Toyone T, Inage K, Sainoh T, Yamauchi K, Takahashi
- KMID: 1793176
- Yonsei Med J.
- 2013 Sep;54(5):1253-1258.
- doi: 10.3349/ymj.2013.54.5.1253
PURPOSE: Osteoarthritic pain is largely considered to be inflammatory pain. Sensory nerve fibers innervating the knee have been shown to be significantly damaged in rat models of knee osteoarthritis (OA)... -
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- Change of Lumbar Ligamentum Flavum after Indirect Decompression Using Anterior Lumbar Interbody Fusion
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Ohtori S, Orita S, Yamauchi K, Eguchi Y, Aoki Y, Nakamura J, Miyagi M, Suzuki M, Kubota G, Inage K, Sainoh T, Sato J, Fujimoto K, Shiga Y, Abe K, Kanamoto H, Inoue G, Takahashi , Furuya T, Koda M
- KMID: 2391594
- Asian Spine J.
- 2017 Feb;11(1):105-112.
- doi: 10.4184/asj.2017.11.1.105
STUDY DESIGN: Retrospective case series. PURPOSE: The purpose of this study was to examine changes in the ligamentum flavum thickness and remodeling of the spinal canal after anterior fusion during a... -
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