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Strategies to Overcome Memory T Cells Mediatied Allograft Injury

Kim BS

  • KMID: 2324212
  • J Korean Soc Transplant.
  • 2012 Jun;26(2):69-73.
During the last few decades our knowledge of transplantation has been remarkably expanded to the point where transplants are a standard treatment modality. However, despite the fact that certain tolerogenic...
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A study of the current(2003-2005) prevalence of anti-HBs and immunologic memory of hepatitis B vaccine in children from the central area of Korea

An YW, Chung EH, Rheem I

PURPOSE: This study was conducted to assess the current(2003-2005) prevalence of anti-HBs and immunologic memory for Hepatitis B vaccine in children from the central area of Korea. METHODS: Subjects were chosen...
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Metabolic Reprogramming by the Excessive AMPK Activation Exacerbates Antigen-Specific Memory CD8⁺ T Cell Differentiation after Acute Lymphocytic Choriomeningitis Virus Infection

Son J, Cho YW, Woo YJ, Baek YA, Kim EJ, Cho Y, Kim JY, Kim BS, Song JJ, Ha SJ

During virus infection, T cells must be adapted to activation and lineage differentiation states via metabolic reprogramming. Whereas effector CD8⁺ T cells preferentially use glycolysis for their rapid proliferation, memory...
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High CD99 expression in memory T and B cells in reactive lymph nodes

Park CK, Shin YK, Kim TJ, Park SH, Ahn GH

We investigated the expression of CD99 in 35 hyperplastic perigastric lymph nodes, which were resected for gastric carcinoma or chronic peptic ulcer. Essentially, all lymphocytes in lymph nodes expressed CD99,...
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Pneumococcal Vaccine

Kim SH, Woo JH

  • KMID: 1482508
  • Hanyang Med Rev.
  • 2008 Aug;28(3):52-57.
Streptococcus pneumoniae causes considerable morbidity and mortality. There are currently two types of pneumococcal vaccine available under license: pneumococcal polysaccharide vaccines(PPV23) and pneumococcal conjugate vaccines(PCV-7). PPV23 contains T-cell independent antigens...
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MicroRNA-mediated Regulation of the Development and Functions of Follicular Helper T cells

Lee J, Park H, Eom J, Kang SG

The germinal center reaction is a key event of humoral immunity, providing long-lived immunological memory. Follicular helper T (T(FH)) cells are a specialized subset of CD4⁺ T cells located in...
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Anti-tumor immunostimulatory effect of heat-killed tumor cells

Yoon TJ, Kim JY, Kim H, Hong C, Lee H, Lee CK, Lee KH, Hong S, Park SH

As a part of our ongoing search for a safe and efficient anti-tumor vaccine, we attempted to determine whether the molecular nature of certain tumor antigens would influence immune responses...
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Assessment of immunological markers and booster effects of Ag85B peptides, Ag85B, and BCG in blood of BCG vaccinated children: a preliminary report

Husain AA, Daginawla , Singh L, Kashyap RS

PURPOSE: In the present study, the protective immunological markers in serum and peripheral blood mononuclear cells (PBMCs) of bacillus Calmette-Guerin (BCG) vaccinated and unvaccinated children were evaluated after vaccination. Further,...
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Combined Treatment of an Intratumoral Injection of Dendritic Cells and Systemic Chemotherapy (Paclitaxel) for Murine Fibrosarcoma

Choi GS, Lee MH, Kim SK, Kim CS, Lee HS, Im MW, Kil HY, Seong DH, Lee JR, Kim WC, Lee MG, Song SU

  • KMID: 2428301
  • Yonsei Med J.
  • 2005 Dec;46(6):835-842.
A novel combined treatment of conventional chemotherapy with an intratumoral injection of syngeneic dendritic cells (DCs) has emerged as a potent cancer treatment strategy. In this study, we evaluated the...
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