- Activation of phosphatidylinositol 4, 5-biphosphate(PIP2) cascade by thyroid stimulating antibody
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Chung JH, Cho BY, Jeon JS, Park KS, Kim SY, Lee HK, Koh CS
- KMID: 1686906
- J Korean Soc Endocrinol.
- 1993 Dec;8(4):422-431.
No abstract available. -
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- Clinical Implication of TSH Receptor Antibody Measurement
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Shin DY
- KMID: 2164911
- Int J Thyroidol.
- 2016 May;9(1):15-18.
- doi: 10.11106/ijt.2016.9.1.15
Autoantibodies directed against the thyrotropin receptor have been well known to be an important pathogenesis of Graves' disease. However, the diagnosis and management of Graves' disease are still mainly dependent... -
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- A Case of Graves' Disease Occurring after Subacute Thyroiditis
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Seo HM, Beom JW, Kim SH, You SY, Kim JY, Koh GP, Lee SA
- KMID: 2269034
- Korean J Med.
- 2015 Aug;89(2):225-228.
- doi: 10.3904/kjm.2015.89.2.225
Graves' disease following subacute thyroiditis is uncommon. Some patients in these cases showed positive for thyroid antibody only transiently in the resolving phase. However, Graves' disease can rarely be caused... -
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- A Case of Neonatal Hyperthyroidism with Unilateral Ear Anomaly
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Chung KO, Kim NY, Cho SM, Lee DS, Kim DK, Choi SM
- KMID: 2207866
- J Korean Pediatr Soc.
- 1998 Jun;41(6):845-849.
Neonatal hyperthyroidism is a very rare disorder occurring typically in the offspring of patients with Graves' disease or chronic thyroiditis. It is caused by the transplacental passage of thyroid stimulating... -
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- Difference of Thyroid Stimulating Antidody Activities Measured in Chinese Hamster Ovary Cells Stably Transfected with Human TSH Receptor and in FRTL-5 Cells in Graves Disease and Its Clinical Correlations
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Young Kee Shong , Park HY, Cho BY, Kim WB, Lee HG, Koh CS, Oh YS
- KMID: 2461601
- J Korean Soc Endocrinol.
- 1996 Mar;11(1):18-29.
Background : Thyroid stimulating antibodies result in the development of hyperthyroidism and goiter in Graves disease. However, thyroid stimulating antibody activities do not correlate with the clinical features in many... -
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- Correlation between the Thyroid Associated Ophthalmopathy and Thyroid Function State
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Rhim WI, Choi SS, Lew H, Yun YS
- KMID: 2109280
- J Korean Ophthalmol Soc.
- 2002 Mar;43(3):431-436.
PURPOSE: To determine the prevalence of thyroid-associated ophthalmopathy (TAO) and the correlation between TAO and the thyroid function state. METHODS: 40 patients with TAO were selected among 2,000 patients of thyroid... -
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- Assay of Thyrotropin Receptor Antibodies with Recombinant Human Thyrotropin Receptor Expressed on Chinese Hamster Ovary Cells
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Cho BY, Lee HK, Koh CS, Chung JH, Yi KH, Ko KS, Kim WB
- KMID: 2462169
- J Korean Soc Endocrinol.
- 1995 Dec;10(4):347-361.
Thyroid stimulating antibody which results in the development of hyperthyroidism and goiter in Graves' patients used to be measured by using rat thyroid cells, FRTL-5. However, this assay has disadvantages:... -
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- Delayed presentation of aggravation of thyrotoxicosis after radioactive iodine therapy at Graves disease
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Lee JH, Na HJ, Park JW, Lee CH, Han HJ, Kim TH, Kim SH
- KMID: 1909826
- Yeungnam Univ J Med.
- 2014 Dec;31(2):148-151.
- doi: 10.12701/yujm.2014.31.2.148
Radioactive iodine (RAI) therapy is widely used for the treatment of Graves disease. After RAI therapy, 44% become hypothyroid and up to 28% remain hyperthyroid. The development of thyrotoxicosis after... -
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- Changes in Thyrotropin Receptor Blocking Antibody after Antithyroid drug Administration to Patients with Atrophic Autoimmune Thyroiditis (Primary Myxedema)
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Kim SY, Cho BY, Lee HK, Chung JH, Koh CS, Shin CS, Kim WB
- KMID: 2461568
- J Korean Soc Endocrinol.
- 1994 Sep;10(3):229-241.
It is well Known that antithyroid drug treatment of Graves' disease suppresses excessive thyroid hormone synthesis and causes a parallel decrease in serum thyroid autoantibody levels including thyroid stimulating antibodies(TSAb)... -
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- Negative correlation between the conversion of thyrotropin receptor-bound blocking type thyrotropin receptor antibody to the stimulating type by anti-human IgG antibodies and the biological activity of blocking type thyrotropin receptor antibody
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Cho BY, Shong MH, Chung JH, Lee HK, Koh CS, Min HK
- KMID: 1422003
- J Korean Med Sci.
- 1993 Oct;8(5):355-360.
- doi: 10.3346/jkms.1993.8.5.355
It has been reported that receptor-bound blocking type TSH receptor antibody (TRAb) can be converted to the stimulating type by anti-human IgG antibodies. To evaluate the relationship between the conversion... -
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- Usefulness of Measuring Thyroid Stimulating Antibody at the Time of Antithyroid Drug Withdrawal for Predicting Relapse of Graves Disease
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Kwon H, Kim WG, Jang EK, Kim M, Park S, Jeon MJ, Kim TY, Ryu JS, Shong YK, Kim WB
- KMID: 2308861
- Endocrinol Metab.
- 2016 Jun;31(2):300-310.
- doi: 10.3803/EnM.2016.31.2.300
BACKGROUND: Hyperthyroidism relapse in Graves disease after antithyroid drug (ATD) withdrawal is common; however, measuring the thyrotropin receptor antibody (TRAb) at ATD withdrawal in order to predict outcomes is controversial.... -
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- Differential Diagnostic Value of Total T3/Free T4 Ratio in Graves' Disease and Painless Thyroiditis Presenting Thyrotoxicosis
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Lee SM, Kim SK, Hahm JR, Jung JH, Kim HS, Kim S, Chung SI, Choi BH, Jung TS
- KMID: 1497650
- Endocrinol Metab.
- 2012 Jun;27(2):121-125.
- doi: 10.3803/EnM.2012.27.2.121
BACKGROUND: It is important to differentiate Graves' disease from that of painless thyroiditis in patients with thyrotoxicosis. In this study, we evaluated the usefulness of total T3 to free T4... -
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- Predictive factors for early response to methimazole in children and adolescents with Graves disease: a single-institute study between 1993 and 2013
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Hwang SM, Kim MS, Lee DY
- KMID: 2328144
- Ann Pediatr Endocrinol Metab.
- 2016 Jun;21(2):70-74.
- doi: 10.6065/apem.2016.21.2.70
PURPOSE: We aimed to investigate the predictive factors for early response to methimazole (MMI) in pediatric patients with Graves disease (GD). METHODS: Our study included 44 pediatric patients who were diagnosed... -
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- Clinical Applications of TSH Receptor Antibodies in Thyroid Diseases
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Cho BY
- KMID: 1101541
- J Korean Med Sci.
- 2002 Jun;17(3):293-301.
- doi: 10.3346/jkms.2002.17.3.293
The cloning and sequencing of thyroid-stimulating hormone (TSH) receptor (TSHR), combined with advances in molecular techniques, have facilitated the understanding of the interaction of the TSHR antibodies (TSHRAbs) with the... -
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- A Case of Thyrotoxicosis with the Presence of Anti-Gastric Parietal Cell Antibodies
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Choi J, Kim TY
- KMID: 1706856
- Lab Med Online.
- 2014 Jul;4(3):172-175.
- doi: 10.3343/lmo.2014.4.3.172
The presence of anti-gastric parietal cell antibodies (AGPAs) has been strongly associated with the pathogenesis of pernicious anemia and atrophic gastritis and has been rarely reported in thyrotoxicosis. In addition,... -
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- A Case of Autoimmune Hepatitis Combined with Graves' Disease
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Jhee JH, Kim HJ, Kang W, Kim S, Kim DY
- KMID: 2373180
- Korean J Gastroenterol.
- 2015 Jan;65(1):48-51.
- doi: 10.4166/kjg.2015.65.1.48
A 25-year-old woman presented with jaundice, palpitation, and weight loss of 5 kg during a period of 2 weeks. Laboratory tests showed elevated levels of liver enzymes (AST 1,282 IU/L,... -
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- Thyroid Stimulating Antibody Assay with Chinese Hamster Ovary Cells Expressing Human Thyroid Stimulating Hormone (TSH) Receptor; Optimization of Assay Condition
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Cho BY, Lee HK, Shong YK, Koh CS, Yi KH, Oh YS, Kim WB
- KMID: 2462168
- J Korean Soc Endocrinol.
- 1995 Dec;10(4):333-346.
We investigated the optimal condition of thyroid stimulating antibody(TSAb) assay using Chinese hamster ovary cells transfected with cDNA of human TSH receptor(TSHr-CHO) stably expressing functional TSH receptors. The extracellular cAMP... -
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- Nonautoimmune congenital hyperthyroidism due to p.Asp633Glu mutation in the TSHR gene
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Cho WK, Ahn MB, Jang W, Chae H, Kim M, Suh BK
- KMID: 2432285
- Ann Pediatr Endocrinol Metab.
- 2018 Dec;23(4):235-239.
- doi: 10.6065/apem.2018.23.4.235
Most cases of congenital hyperthyroidism are autoimmune forms caused by maternal thyroid stimulating antibodies. Nonautoimmune forms of congenital hyperthyroidism caused by activating mutations of the thyrotropin receptor (TSHR) gene are... -
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- Measurements of Thyroid Stimulation Blocking Antibody Activities by Chinese Hamster Ovary ( CHO ) cells Expressing Human TSH Receptors in Patients with Primary Hypothyroidism
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Kim WB, Cho BY, Park DJ
- KMID: 2100243
- J Korean Soc Endocrinol.
- 1997 Mar;12(1):18-32.
BACKGROUND: The Chinese hamster ovary cells transfected with human TSH receptor cDNA (hTSHR-CHO), expressing functional human TSH receptors, are known to be more sensitive in detection of thyroid stimulating antibodies... -
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- Clinical Usefulness of the Second Generation TSH-Binding Inhibitory Immunoglobulin Assay Using Recombinant Human TSH Receptor in Patients with Graves' Disease
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Huh JE, Suk JH, Kim MK, Choi IJ, Son SM, Kim IJ, Kim YK
- KMID: 1479204
- J Korean Endocr Soc.
- 2008 Jun;23(3):179-185.
- doi: 10.3803/jkes.2008.23.3.179
BACKGROUND AND AIM: Detection of TSH receptor antibody in patients with Graves' disease (GD) has been widely used in clinical practice. This has been performed mostly by commercial radio-receptor assays... -
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