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Long Term Safety and Efficacy of Abatacept in Patients with Rheumatoid Arthritis

Lee CK

No abstract available.
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Long-term Safety and Efficacy of Abatacept in Koreans with Rheumatoid Arthritis

Shim SC, Park SH, Bae SC, Choe JY, Song YW, Mitra P, Karyekar C

OBJECTIVE: The safety and efficacy of intravenous (IV) abatacept in patients with active RA unresponsive to methotrexate have been demonstrated in short-term (ST) studies in global populations and a ST,...
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Description of the Efficacy and Safety of Three New Biologics in the Treatment of Rheumatoid Arthritis

Storage SS, Agrawal H, Furst DE

English articles on abatacept, golimumab, and tocilizumab in rheumatoid arthritis published between 2002 and 2009 were reviewed systematically. All randomized clinical trials, open-label extensions, meta-analyses, and reviews were examined. There...
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New drugs for Rheumatoid arthritis

Seo YI

  • KMID: 2257380
  • Korean J Med.
  • 2009 Jan;76(1):12-17.
Since the late 1990s, based on scientific advancement and biotechnological improvement, many effective drugs such as leflunomide and biologic agents for rheumatoid arthritis (RA) have been developed. These include TNF-alpha...
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Human Cytotoxic T Lymphocyte-associated Antigen 4-immunoglobulin Fusion Protein Inhibits Airway Inflammation and Hyperresponsiveness in a Murine Model of Asthma

  • KMID: 2234531
  • Korean J Asthma Allergy Clin Immunol.
  • 2008 Sep;28(3):205-213.
BACKGROUND: CD4+ T helper cells which differentiate into the Th2 cells are crucial for the initiation and progression of allergic asthma. Human Cytotoxic T Lymphocyte- associated Antigen 4-immunoglobulin (CTLA4-Ig) has...
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IL-2 Pathway Blocking in Combination with Anti-CD154 Synergistically Establishes Mixed Macrochimerism with Limited Dose of Bone Marrow Cells and Prolongs Skin Graft Survival in Mice

Lee JH, Ha J, Kim SH, Kim SJ

To facilitate the establishment of mixed chimerism with limited dose of bone marrow (BM) cells, and to achieve tolerance in skin graft model, combined blocking of costimulatory pathway and IL-2...
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Radioimmunotherapy (I): Development of Radioimmunoconjugates

Choi TH, Lim SM

  • KMID: 2313015
  • Nucl Med Mol Imaging.
  • 2006 Apr;40(2):66-73.
Monoclonal antibodies are designed to bind specifically to certain antigen, give therapeutic effect to the target and to be produced in large scale with homogeneity. The monoclonal antibodies conjugated with...
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The Basic Studies on the Application of Galectin - 3 as a Target Protein for Delivering Anticancer Agents

Woo HJ, Joo HG

  • KMID: 1547844
  • Korean J Immunol.
  • 1997 Mar;19(1):83-90.
Gastric cancer cells express large amounts of galectin-3 on the cell surface. This fact may provide the possibility to use galectin-3 protein as a surface target for delivering cytotoxic anticancer...
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