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Two Cases of Pediatric Obstructive Hypoventilation Managed with Upper Airway Surgery

Kim TM, Hong SN, Yoo JH, Lee SH

Sleep-disordered breathing in children can include habitual snoring, obstructive hypoventilation, upper airway resistance syndrome, and obstructive sleep apnea. Obstructive hypoventilation in children is characterized by COâ‚‚ retention caused by prolonged...
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Anesthetic Experience of a Patient with Chronic Hypoventilation Syndrome: A case report

Han SM, Kwak HJ, Lee MA

Alveolar hypoventilation exists by definition when arterial PaCO2 increases above the normal range of 37 to 42 mmHg, but in clinically important hypoventilation syndromes PaCO2 is generally in the range...
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A case of congenital central hypoventilation syndrome(ondine's curse) with hirschsprung's disease

Ahn YM, Choi HR, Lee HJ, Dong ES

  • KMID: 1690734
  • Pediatr Allergy Respir Dis.
  • 1993 Sep;3(1):113-120.
No abstract available.
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Spinal anesthesia and postoperative epidural analgesia in a patient with congenital central hypoventilation syndrome: a case report

Choi Y, Lee S, Lee J, Woo S

BACKGROUND: Congenital central hypoventilation syndrome (CCHS) is a rare disorder characterized by alveolar hypoventilation and autonomic dysregulation. Patients with CCHS have adequate ventilation while awake but exhibit hypoventilation while asleep....
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Central Hypoventilation Syndrome during Awake and Sleep

Kim HS, Park SM, Han SR, Kim YI

  • KMID: 2065462
  • J Korean Neurol Assoc.
  • 2000 Sep;18(5):645-649.
Central hypoventilation syndrome (CHS) can be caused by any lesions to the medullary respiratory centers, cerebral cortex, corticospinal pathways, and their connections. We report 5 patients with central hypoventilation syndrome...
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A Case of Severe Obesity-Hypoventilation Syndrome Treated by Bilevel Positive Airway Pressure Therapy

Kim HJ, Hong S, Han JK, Kim BJ, Park KW, Lee DH, Oh K, Sim WJ, Park SS, Shin SY

  • KMID: 1852270
  • J Korean Neurol Assoc.
  • 2005 Dec;23(6):836-839.
Obesity-Hypoventilation syndrome (OHS) is characterized by morbid obesity, hypoxia, and hypercapnea during wakefulness without parechymal lung disease or severe obstructive sleep apnea. A woman was admitted because of mental deterioration...
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Hypoventilation and hypokalemia in a patient with poor oral intake in the postanesthesia care unit: A case report

Yi YR, Hwang BM

  • KMID: 2169110
  • Anesth Pain Med.
  • 2012 Apr;7(2):170-173.
We encountered a case of hypoventilation and hypokalemia in a patient with poor oral intake in the postanesthesia care unit (PACU). A 44-year-old woman underwent a total abdominal hysterectomy under...
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A case of juvenile form Pompe's disease manifested as chronic alveolar hypoventilation

Kim DG, Jung K, Lee MK, Hyun IG, Lim HJ, Song HG, Chi JG

We describe a case of the juvenile form of Pompe's disease that presented as primary alveolar hypoventilation due to respiratory muscle involvement. This 17-year-old girl had been asymptomatic until this...
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Haddad Syndrome with PHOX2B Gene Mutation in a Korean Infant

Lee CW, Lee JH, Jung EY, Choi SO, Kim CS, Lee SL, Kim DK

Congenital central hypoventilation syndrome with Hirschsprung's disease, also known as Haddad syndrome, is an extremely rare disorder with variable symptoms. Recent studies described that congenital central hypoventilation syndrome had deep...
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Hypercapnic Respiratory Failure Immediate After Bariatric Surgery

Jo YY, Jung WS, Park HY, Chang YJ

Surgery and general anesthesia can both lead to impaired lung function, abnormal gas exchange and abnormal respiratory mechanics in obese patients. A 37 year old obese female who had obesity...
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Respiratory Failure Induced by Severe Hypothyroidism in a Korean Woman

Kwon H, Kim BR, Han SS, Hong Y

A 76-year-old Korean woman visited to emergency room because of respiratory arrest and admitted to intensive care unit of the hospital. Severe hypothyroidism was diagnosed after repeated failure of weaning...
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A Case of Myxedema Coma with Severe Hypoventilation

Shim JY, Lee SW, Lee HW, Choi JH, Song YJ, Lee HS, Chung YS, Lee KW

  • KMID: 1837627
  • J Korean Soc Endocrinol.
  • 2004 Apr;19(2):203-208.
A myxedema coma, representing the extreme feature of hypothyroidism is rare. Despite early vigorous treatment, a myxedema coma is associated with a mortality rate as high as 60%. Herein, a...
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Neurocristopathy Combined with Congenital Central Hypoventilation Syndrome, Hirschsprung's Disease and Ganglioneuroblastoma in a Neonate

Jung SE, Kim DY, Kim KH, Lee SC, Park KW, Kim WK

Neurocristopathy is characterized as having a common origin in aberrant neural crest development. Congenital central hypoventilation syndrome (Ondine's curse) is characterized by marked depression of respiratory drive during sleep and...
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Utility of end-tidal carbon dioxide monitoring in intramuscular ketamine sedation in the pediatric emergency department

Yang HJ, Seo HY, Kwak JR, Lee JS

PURPOSE: Recently, the use of end-tidal carbon dioxide (ETCOâ‚‚) monitoring has been suggested for early detection of hypoventilation over oxygen saturation (S(P)Oâ‚‚) monitoring. We aimed to determine the usefulness of...
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Sleep-Related Respiratory Disturbances

Moon HS

  • KMID: 2317243
  • Sleep Med Psychophysiol.
  • 1995 Jun;2(1):55-64.
During sleep, relatively major respiratory physiological changes occur in healthy subjects. The contributions and interactions of voluntary and metabolic breathing control systems during waking and sleep are quite different. Alterations...
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Dental Treatment of a 3-Year-Old Male Patient with Haddad Syndrome under Outpatient General Anesthesia

Jang JH, Shin TJ, Kim YJ, Kim JW, Jang KT, Lee SH, Kim CC, Hyun HK

The co-occurrence of congenital central hypoventilation syndrome (CCHS) and Hirschsprung's disease (HD) is termed Haddad syndrome, which is an extremely rare disorder. It was reported first by Haddad in 1978...
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Molecular genetics of congenital central hypoventilation syndrome and Haddad syndrome

Lee JH, Kim DK

Congenital central hypoventilation syndrome (CCHS) is a disorder of the autonomic nervous system characterized by a decreased response to hypercarbia. CCHS is frequently associated with congenital megacolon; the combination is...
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A Case of Rapidly Developed Obesity Hypoventilation Syndrome in a Patient with Kyphoscoliosis

Kim MY, Jeong JS, Jang YN, Go SE, Lee SH, Moon HS, Kang HH

Obesity hypoventilation syndrome (OHS) is characterized by severe obesity, excessive daytime sleepiness, hypoxemia and hypercapnea. Because OHS mimics pulmonary hypertension or cor pulmonale, clinicians should recognize and treat this syndrome...
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Haddad Syndrome with 27 Polyalanine Repeats in PHOX2B Gene in a Korean Infant

Kim SJ, Cho YS, Choi YJ, Chung JH, Jung MH, Lee SJ, Sung IK, Kim SY

  • KMID: 2280845
  • Korean J Perinatol.
  • 2011 Dec;22(4):356-361.
Haddad syndrome is an extremely rare disorder which combines congenital central hypoventilation syndrome (CCHS) and Hirschsprung's disease. Several reports have demonstrated that CCHS was related to mutation of the PHOX2B...
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A Case of Congenital Central Hypoventilation Syndrome with PHOX2B Gene Mutation in a Korean Neonate

Kwon KA, Park SE, Byun SY, Kim SY, Hwang SH

Congenital central hypoventilation syndrome (CCHS) is a life-threatening disorder with apnea and cyanosis during sleep requiring immediate endotracheal intubation during the first day of life. The PHOX2B gene has been...
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