- PPARgamma Agonist and Angiotensin II Receptor Antagonist Ameliorate Renal Tubulointerstitial Fibrosis
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Han JY, Kim YJ, Kim L, Choi SJ, Park IS, Kim JM, Chu YC, Cha DR
- KMID: 1713829
- J Korean Med Sci.
- 2010 Jan;25(1):35-41.
- doi: 10.3346/jkms.2010.25.1.35
The peroxisome proliferator activated receptor (PPAR)gamma agonist is used as antidiabetic agent with antihyperglycemic and antihyperinsulinemic actions. Beyond these actions, antifibrotic effects have been reported. We examined antifibrotic effects of... -
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- Role of protease inhibitors and acylation stimulating protein in the adipogenesis in 3T3-L1 cells
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Soliman MM, El-Senosi , Salem MM, Hamid OM, Kazuhiro K
- KMID: 1726918
- J Vet Sci.
- 2009 Sep;10(3):197-201.
- doi: 10.4142/jvs.2009.10.3.197
Treatment of AIDS (HIV) and hepatitis C virus needs protease inhibitors (PI) to prevent viral replication. Uses of PI in therapy are usually associated with a decrease in body weight... -
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- B cell activation factor (BAFF) is a novel adipokine that links obesity and inflammation
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Kim YH, Choi BH, Cheon HG, Do MS
- KMID: 1123468
- Exp Mol Med.
- 2009 Mar;41(3):208-216.
- doi: 10.3858/emm.2009.41.3.024
B cell activation factor (BAFF) is a novel member of the TNF ligand superfamily, mainly produced by myeloid cells. BAFF has been shown to participate in B-cell survival and B-... -
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- 15-Deoxy-delta12,14-PGJ2inhibits IL-6-induced Stat3 phosphorylation in lymphocytes
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Kim HJ, Rho YH, Choi SJ, Lee YH, Cheon HJ, Um JW, Sohn J, Song GG, Ji JD
- KMID: 1056229
- Exp Mol Med.
- 2005 Jun;37(3):179-185.
15-deoxy-delta12,14-PGJ2(15d-PGJ2) is a natural ligand that activates the peroxisome proliferators-activated receptor (PPAR) gamma, a member of nuclear receptor family implicated in regulation of lipid metabolism and adipocyte differentiation. Recent studies... -
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- Expression and Regulation of Osteoprotegerin in Adipose Tissue
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An JJ, Han DH, Kim DM, Kim SH, Rhee Y, Lee EJ, Lim SK
- KMID: 1122612
- Yonsei Med J.
- 2007 Oct;48(5):765-772.
- doi: 10.3349/ymj.2007.48.5.765
PURPOSE: Osteoprotegerin (OPG), a potent inhibitor of osteoclastic bone resorption, has a variety of biological functions that include anti-inflammatory effects. Adipocytes and osteoblasts share a common origin, and the... -
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- Sulfuretin protects against cytokine-induced beta-cell damage and prevents streptozotocin-induced diabetes
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Song MY, Jeong GS, Kwon KB, Ka SO, Jang HY, Park JW, Kim YC, Park BH
- KMID: 983955
- Exp Mol Med.
- 2010 Sep;42(9):628-638.
- doi: 10.3858/emm.2010.42.9.062
NF-kappaB activation has been implicated as a key signaling mechanism for pancreatic beta-cell damage. Sulfuretin is one of the main flavonoids produced by Rhus verniciflua, which is reported to inhibit... -
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- Activation of PPARgamma induces profound multilocularization of adipocytes in adult mouse white adipose tissues
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Koh YJ, Park BH, Park JH, Han J, Lee IK, Park JW, Koh GY
- KMID: 1099865
- Exp Mol Med.
- 2009 Dec;41(12):880-895.
- doi: 10.3858/emm.2009.41.12.094
We sought to determine the effects of activation of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) on multilocularization of adipocytes in adult white adipose tissue (WAT). Male C57BL/6 normal, db/db, and ob/ob mice... -
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