- A Case of Mania Associated with Hypericum Perforatum in a Patient with Major Depression
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Lee KK, Lim MH, Kang YK, Lee JH, Paik KC, Kim HW
- KMID: 1607284
- Korean J Psychopharmacol.
- 2001 Jun;12(2):151-156.
Recently Korean Food and Drug Administration approved Hypericum perforatum preparations (St. John's wort) as an over-the-counter drug. The authors reported a case of Hypericum perforatum induced mania in a patient... -
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- Hypericum Perforatum Decreased Hippocampus TNF-alpha and Corticosterone Levels with No Effect on Kynurenine/Tryptophan Ratio in Bilateral Ovariectomized Rats
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El-Bakly W, Hasanin AH
- KMID: 2285515
- Korean J Physiol Pharmacol.
- 2014 Jun;18(3):233-239.
- doi: 10.4196/kjpp.2014.18.3.233
The present study was designed to investigate the effect Hypericum Perforatum (HP), on behavioral changes, corticosterone, TNF-alpha levels and tryptophan metabolism and disposition in bilateral ovariectomized rats compared to 17alpha... -
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- Effect of St. John's Wort (Hypericum perforatum) on obesity, lipid metabolism and uterine epithelial proliferation in ovariectomized rats
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You MK, Rhuy J, Jeong KS, Bang MA, Kim MS, Kim HA
- KMID: 2313742
- Nutr Res Pract.
- 2014 Jun;8(3):292-296.
BACKGROUND/OBJECTIVES: This study was conducted to assess the potential of St. John's Wort (Hypericum perforatum) to prevent obesity and abnormalities in lipid metabolism induced by ovariectomy in a rat model... -
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- Black Cohosh and St. John's Wort (GYNO-Plus(R)) for Climacteric Symptoms
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Chung DJ, Kim HY, Park KH, Jeong KA, Lee SK, Lee YI, Hur SE, Cho MS, Lee BS, Bai SW, Kim CM, Cho SH, Hwang JY, Park JH
- KMID: 1779533
- Yonsei Med J.
- 2007 Apr;48(2):289-294.
- doi: 10.3349/ymj.2007.48.2.289
PURPOSE: This study was conducted to investigate the efficacy of black cohosh (Cimicifuga racemosa) and St. John's wort (Hypericum perforatum) in women with climacteric symptoms, and to assess their effects... -
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- Hypericin, a Naphthodianthrone Derivative, Prevents Methylglyoxal-Induced Human Endothelial Cell Dysfunction
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Do MH, Kim SY
- KMID: 2375035
- Biomol Ther.
- 2017 Mar;25(2):158-164.
- doi: 10.4062/biomolther.2016.034
Methylglyoxal (MGO) is a highly reactive metabolite of glucose which is known to cause damage and induce apoptosis in endothelial cells. Endothelial cell damage is implicated in the progression of... -
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- St. John's Wort (Hypericum perforatum) stimulates human osteoblastic MG-63 cell proliferation and attenuates trabecular bone loss induced by ovariectomy
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You MK, Kim DW, Jeong KS, Bang MA, Kim HS, Rhuy J, Kim HA
- KMID: 2313865
- Nutr Res Pract.
- 2015 Oct;9(5):459-465.
- doi: 10.4162/nrp.2015.9.5.459
BACKGROUND/OBJECFTIVES: The effect of St. John's Wort extract (SJW) on MG-63 cell proliferation and trabecular bone loss induced by ovariectomy was examined. MATERIALS/METHODS: Proliferation, expression of estrogen receptor (ER) alpha and... -
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- Hyperoside Induces Endogenous Antioxidant System to Alleviate Oxidative Stress
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Park JY, Han X, Piao MJ, Oh MC, Fernando P, Kang KA, Ryu YS, Jung U, Kim IG, Hyun JW
- KMID: 2161522
- J Cancer Prev.
- 2016 Mar;21(1):41-47.
- doi: 10.15430/JCP.2016.21.1.41
BACKGROUND: Hyperoside, a flavonoid which is mainly found in Hypericum perforatum L., has many biological effects. One of the most important effects is to prevent the oxidative stress induced by... -
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- Non-pharmacological treatment for depression
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Park YC
- KMID: 2190418
- J Korean Med Assoc.
- 2011 Apr;54(4):376-380.
- doi: 10.5124/jkma.2011.54.4.376
In treatment of depression, non-pharmacological treatment is as important as pharmacological treatment. However, in clinical practice in Korea, non-pharmacological treatment is not provided sufficiently and patients are not satisfied with... -
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- The treatments of Anxious Depression
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Kim HS
- KMID: 2286943
- Korean J Psychopharmacol.
- 2000 Jun;11(2):111-116.
Anxiety symptoms and disorders frequently coexist in patients with major depression. Two conditions show extentive overlap with respect to symptomatology and a spectrum of disorders. The majority of patients were found to... -
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- The efficacy and safety of the combined preparation of Black Cohosh and St. John's wort in menopausal women
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Park HB, Kang YD, Cho HC, Lee WK, Park JW
- KMID: 2273094
- Korean J Obstet Gynecol.
- 2007 Jan;50(1):142-148.
OBJECTIVE: The aim of this study was to assess the efficacy and safety of the combined preparation of black cohosh and St. John's wort (GYNO-Plus(R)) in post menopausal women with... -
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- Self Care in Depression
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Lee SH, Park YC
- KMID: 2249202
- Korean J Biol Psychiatry.
- 2007 Feb;14(1):5-13.
OBJECTIVES: Depression disturbs the individual life from the loss of productivity to suicide. Furthermore the whole society is also influenced by depression in social and economic areas. Many scientific treatment... -
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- The Effect of black cohosh with St. John's wort (Feramin-Q(R)) on climacteric symptoms: multicenter randomized double-blind placebo-controlled trial
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Park HM, Kang BM, Kim JG, Yoon BK, Lee BI, Cho SH, Choi H, Yu BH
- KMID: 2272710
- Korean J Obstet Gynecol.
- 2005 Oct;48(10):2403-2413.
OBJECTIVE: Results of several recent randomized clinical trials and epidemiological studies casted many doubts about the validity and safety of conventional hormone therapy for postmenopausal women. More and more women... -
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