- Topical Hypopigmenting Agents for Pigmentary Disorders and Their Mechanisms of Action
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Kim H, Choi HR, Kim DS, Park KC
- KMID: 2156847
- Ann Dermatol.
- 2012 Feb;24(1):1-6.
- doi: 10.5021/ad.2012.24.1.1
Melanin is produced in melanocytes and stored in melanosomes. In spite of its beneficial sun-protective effect, abnormal accumulation of melanin results in esthetic problems. Hydroquinone, competing with tyrosine, is a... -
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- The Difference in Biological Properties between Parental and v-Ha-ras Transformed NIH3T3 Cells
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Lee M, Ahn JH, Eum KH
- KMID: 2165985
- Cancer Res Treat.
- 2009 Jun;41(2):93-99.
PURPOSE: We performed experiments to investigate the change in cellular signaling that occurs during the transformation of a normal cell to a cell capable of cancerous growth, and we did... -
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- Downregulation of NFAT2 promotes melanogenesis in B16 melanoma cells
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Lee YS, Kim DW, Kim S, Choi HI, Lee Y, Kim CD, Lee JH, Lee SD, Lee YH
- KMID: 1455344
- Anat Cell Biol.
- 2010 Dec;43(4):303-309.
- doi: 10.5115/acb.2010.43.4.303
Nuclear factor of activated T-cells (NFAT) proteins are, calcium-regulated transcription factors, key regulator of stimulation-dependent gene activation. In our microarray analysis for the genes expressed in human black and white... -
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- Endothelium-dependent vasodilation by ferulic acid in aorta from chronic renal hypertensive rats
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Choi S, Kim HI, Park SH, Lee MJ, Jun JY, Kim HL, Chung JH, Yeum CH
- KMID: 1426333
- Kidney Res Clin Pract.
- 2012 Dec;31(4):227-233.
BACKGROUND: Ferulic acid (FA) is a naturally occurring nutritional compound. Although it has been shown to have antihypertensive effects, its effects on vascular function have not been intensively established. The... -
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- The Production and Functions of Reactive Oxygen Species in Mouse Bone Marrow-derived Dendritic Cells by Various Haptens and Irritants
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Kim DS, Kim DH, Byamba D, Lee TH, Cho YH, Lee MG
- KMID: 2248021
- Korean J Dermatol.
- 2008 Nov;46(11):1470-1477.
BACKGROUND: Various allergens and irritants induced the production of reactive oxygen species (ROS) in the well-established mouse dendritic cell (DC) line XS106 and this production of ROS was inhibited by... -
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- Enhancement of radiation effect using beta-lapachone and underlying mechanism
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Ahn KJ, Lee HS, Bai SK, Song CW
- KMID: 2051119
- Radiat Oncol J.
- 2013 Jun;31(2):57-65.
- doi: 10.3857/roj.2013.31.2.57
Beta-lapachone (beta-Lap; 3,4-dihydro-2, 2-dimethyl-2H-naphthol[1, 2-b]pyran-5,6-dione) is a novel anti-cancer drug under phase I/II clinical trials. beta-Lap has been demonstrated to cause apoptotic and necrotic death in a variety of human... -
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- EFFECTS OF HYDROQUINONE ON NEOPLASTIC TRANSFORMATION OF HUMAN EPITHELIAL CELLS IN CULTURE
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Sohn JH, Kim CS
- KMID: 2186578
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2010 May;32(3):218-228.
Components of dental resin-based restorative materials are reported to leach from the filling materials even after polymerization. Hydroquinone (HQ) is one of the major monomers used in the dental resin... -
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