- Hydrogen peroxide mediates doxorubicin-induced transglutaminase 2 expression in PC-14 human lung cancer cell line
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Han JA, Park SC
- KMID: 1029936
- Exp Mol Med.
- 1999 Jun;31(2):83-88.
Increased expression of Transglutaminases 2 (TGase 2, TGase C) was observed in PC-14 human lung cancer cells in association with doxorubicin resistance and the reduction of the enzyme expression was correlated with... -
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- Redox signaling: hydrogen peroxide as intracellular messenger
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Rhee SG
- KMID: 1029931
- Exp Mol Med.
- 1999 Jun;31(2):53-59.
Although superoxide anions (O2.-) and H2O2 are generally considered to be toxic by-products of respiration, recent evidence suggests that the production of these reactive oxygen species (ROS) might be an integral component... -
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- Selective inhibition of polymorphonuclear leukocytes by immunosuppressive concentration of prostaglandin E2
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Hong YS
- KMID: 932125
- J Korean Med Sci.
- 1996 Feb;11(1):8-16.
- doi: 10.3346/jkms.1996.11.1.8
Prostaglandin E2(PGE2) has been implicated as an immunosuppressive agent and plasma levels of PGE2 are elevated in patients sustaining thermal injury. We examined the effect of 10(-7) M prostaglandin E2(PGE2)... -
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- Ischemic preconditioning in the rat hippocampus increases antioxidant activities but does not affect the level of hydroxyl radicals during subsequent severe ischemia
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Choi YS, Cho KO, Kim EJ, Sung KW, Kim SY
- KMID: 756079
- Exp Mol Med.
- 2007 Aug;39(4):556-563.
Several studies have demonstrated that ischemic preconditioning increases superoxide dismutase activity, but it is unclear how ischemic preconditioning affects events downstream of hydrogen peroxide production during subsequent severe ischemia and... -
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- Tempol Attenuates Renal Fibrosis in Mice with Unilateral Ureteral Obstruction: The Role of PI3K-Akt-FoxO3a Signaling
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Yoon HE, Kim SJ, Kim SJ, Chung S, Shin SJ
- KMID: 1789980
- J Korean Med Sci.
- 2014 Feb;29(2):230-237.
- doi: 10.3346/jkms.2014.29.2.230
This study investigated whether tempol, an anti-oxidant, protects against renal injury by modulating phosphatidylinositol 3-kinase (PI3K)-Akt-Forkhead homeobox O (FoxO) signaling. Mice received unilateral ureteral obstruction (UUO) surgery with or without... -
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- Oxidative stress is associated with the number of components of metabolic syndrome: LIPGENE study
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Yubero-Serrano EM, Delgado-Lista J, Pena-Orihuela P, Perez-Martinez P, Fuentes F, Marin C, Tunez I, Jose Tinahones F, Perez-Jimenez F, Roche HM, Lopez-Miranda J
- KMID: 2154247
- Exp Mol Med.
- 2013 Jun;45(6):e28.
Previous evidence supports the important role that oxidative stress (OxS) plays in metabolic syndrome (MetS)-related manifestations. We determined the relationship between the number of MetS components and the degree of... -
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- Anti-inflammatory effects of IL-4 and IL-10 on Human Polymorphonuclear Leukocytes
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Lee SW, Hong YS, Chun CM, Moon JD, Kim SJ, Jung IC, Yoon YH, Lee BA, Moon SW, Choi SH, Moon CK
- KMID: 2157586
- J Korean Med Sci.
- 2002 Feb;17(1):7-14.
- doi: 10.3346/jkms.2002.17.1.7
Inflammatory responses are strictly regulated by coordination of pro-inflammatory and anti-inflammatory mediators. Interleukin-4 (IL-4) and interleukin-10 (IL-10) have typically the biologic anti-inflammatory effects on monocytes, but uncertain effects on polymorphonuclear... -
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- Role of Ca(2+) in diallyI disulfide-induced apoptotic cell death of HCT-15 cells.
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Park EK, Kwon KB, Park KI, Park BH, Jhee EC
- KMID: 1380234
- Exp Mol Med.
- 2002 Jul;34(3):250-257.
Diallyl disulfide (DADS) induced apoptosis through the caspase-3 dependent pathway in leukemia cells was earlier reported from this laboratory. In this study, we investigated the involvement of Ca(2+) in DADS-induced... -
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- Cloning and characterization of a selenium-independent glutathione peroxidase (HC29) from adult Haemonchus contortus
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Sun W, Song X, Yan R, Xu L, Li X
- KMID: 1365003
- J Vet Sci.
- 2012 Mar;13(1):49-58.
- doi: 10.4142/jvs.2012.13.1.49
The complete coding sequence of Haemonchus (H.) contortus HC29 cDNA was generated by rapid amplification of cDNA ends in combination with PCR using primers targeting the 5'- and 3'-ends of... -
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